Stafford Vigors

ORCID: 0000-0002-9304-2925
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Research Areas
  • Animal Nutrition and Physiology
  • Meat and Animal Product Quality
  • Genetic and phenotypic traits in livestock
  • Gut microbiota and health
  • Animal Behavior and Welfare Studies
  • Rabbits: Nutrition, Reproduction, Health
  • Agriculture Sustainability and Environmental Impact
  • Selenium in Biological Systems
  • Ruminant Nutrition and Digestive Physiology
  • Seaweed-derived Bioactive Compounds
  • Regulation of Appetite and Obesity
  • Biochemical Analysis and Sensing Techniques
  • Probiotics and Fermented Foods
  • Food and Agricultural Sciences
  • Clinical Nutrition and Gastroenterology
  • Effects of Environmental Stressors on Livestock
  • NF-κB Signaling Pathways
  • Immune Response and Inflammation
  • Microbial Metabolites in Food Biotechnology
  • Moringa oleifera research and applications
  • Phytase and its Applications
  • Vitamin D Research Studies
  • Helicobacter pylori-related gastroenterology studies
  • Zoonotic diseases and public health
  • Milk Quality and Mastitis in Dairy Cows

University College Dublin
2016-2025

Agriculture and Food
2022

European Federation of Animal Science
2021

Cambridge University Press
2014

New York University Press
2014

Feed efficiency is an important trait in pig production, with evidence to suggest that the efficiencies of a variety biological systems contribute variation this trait. Little work has been conducted on contribution intestinal innate immune response divergence feed efficiency. Hence, objective study was examine select bacterial populations and gene expression profiles range targets relating gut health immunity intestine pigs phenotypically divergent in: a) basal state; (b) following ex-vivo...

10.1371/journal.pone.0148145 article EN cc-by PLoS ONE 2016-02-03

Feed efficiency is an important trait in the future sustainability of pig production, however, mechanisms involved are not fully elucidated. The objective this study was to examine nutrient digestibility, organ weights, select bacterial populations, volatile fatty acids (VFA’s), enzyme and intestinal transporter gene expression a population divergent feed efficiency. Male pigs (n=75; initial BW 22.4 kg SEM 2.03 kg) were fed standard finishing diet for 43 days before slaughter evaluate intake...

10.1017/s1751731116000847 article EN cc-by-nc-nd animal 2016-01-01

Dietary supplementation with 300 ppm of a laminarin rich macroalgal extract reduces post-weaning intestinal dysfunction in pigs. A comprehensive analysis the impact on microbiome during this period is essential to inform mode action bioactivity. The objective study was evaluate effects supplementing diet newly weaned pigs extract, animal performance, volatile fatty acids, and microbiota using 16S rRNA gene sequencing. Pigs fed laminarin-supplemented had higher average daily feed intake,...

10.3390/md18030157 article EN cc-by Marine Drugs 2020-03-11

There is an urgent need to identify natural bioactive compounds that can enhance gastrointestinal health and promote pig growth performance in the absence of pharmacological levels zinc oxide (ZnO). The objectives this study were to: 1) compare effects mushroom powder supplemented with inorganic selenium (inSeMP) enriched organic (orgSeMP) ZnO on faecal scores (FS) for first 21 d post-weaning (Period 1); 2) molecular microbial inSeMP orgSeMP these pigs 39 2).

10.1186/s40104-022-00808-x article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2023-01-11

The improvement of feed efficiency is a key economic goal within the pig production industry. objective this study was to examine transcriptomic differences in both liver and muscle pigs divergent for efficiency, thus improving our understanding molecular mechanisms influencing enabling identification candidate biomarkers. Residual intake (RFI) calculated two populations from different farms origin/genotype. 6 most efficient (LRFI) least (HRFI) animals each population were selected further...

10.1186/s12864-019-5740-z article EN cc-by BMC Genomics 2019-06-06

Restriction in antimicrobial use broiler chicken production is driving the exploration of alternative feed additives that will support growth through promotion gastrointestinal health and development. The objective this study was to determine effects dietary inclusion laminarin on performance, expression nutrient transporters, markers inflammation intestinal integrity small intestine composition caecal microbiota chickens. Two-hundred-and-forty day-old male Ross 308 chicks (40.64 (3.43 SD)...

10.1016/j.psj.2021.101179 article EN cc-by-nc-nd Poultry Science 2021-04-21

Ruminants excrete both undigested and excess consumed nitrogen (N) through feces urine, which results in the waste of feed protein environmental pollution. This study aims to screen bacteria identify strains with potential improve utilization rumen. In a tube screening test, when 30 mmol/L ammonium sulfate was added as only source liquid medium, among 115 bacterial belonging Bacillus lactic-acid bacteria, 10 highest growth (OD600nm level) comparison other evaluated were identified, these,...

10.3389/fmicb.2024.1498109 article EN cc-by Frontiers in Microbiology 2025-01-17

Reducing crude protein (CP) in weaner pig diets lowers post-weaning diarrhoea risk but may impair growth performance. This study aimed to identify benefical effects of organic acid (OA)-preserved grain and butyric (BA) supplementation on gut health low-CP diets. At harvest, was divided into 2 batches: one dried at 65 °C, the other treated with a propionic acid. Ninety-six piglets (28 days old) were assigned four treatments: (1) grain, (2) OA-preserved (3) grain+3% BA, (4) BA. On day 8,...

10.20944/preprints202502.0266.v1 preprint EN 2025-02-05

This study investigated whether organic acid (OA)-preserved grain could mitigate the negative effects of low crude protein (CP) diets on growth performance, intestinal health, and coefficient total tract digestibility (CATTD) nutrients in weaned piglets. The was either conventionally dried or preserved post-harvest with 4 kg OA per tonne. Ninety-six piglets (28 days old) were assigned to one four a 2 × factorial design: (1) standard CP diet, (2) OA-preserved (3) (4) diet. Standard contained...

10.3390/ani15050702 article EN cc-by Animals 2025-02-27

Abstract Background Organic acids (OA) and maternal nutritional strategies have been demonstrated to promote piglet health development. The objective of this study was investigate the effects incorporating OA-preserved cereal grains into sow diets during late gestation lactation, aiming reduce metabolic demands lactation while optimising offspring development growth until slaughter. experiment compared wheat barley conventionally dried grains, focusing on performance, as well their faecal...

10.1186/s40104-025-01171-3 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2025-03-12

Reducing crude protein (CP) in weaner pig diets lowers post-weaning diarrhoea risk but may impair growth performance. This study aimed to identify the beneficial effects of organic acid (OA)-preserved grain and butyric supplementation on gut health low-CP diets. At harvest, was divided into two batches: one dried at 65 °C, other treated with a propionic acid. Ninety-six piglets (28 days old) were assigned four treatments: (1) grain, (2) OA-preserved (3) + 3% acid, (4) On day 8, microbial...

10.3390/microorganisms13030689 article EN cc-by Microorganisms 2025-03-19

Phytase (PHY) improves growth performance, nutrient digestibility and bone structure in pigs; however, little is known about its effects on intestinal transporter gene expression. In the present study, a 44 d experiment was carried out using forty-eight pigs (11·76 ( sem 0·75) kg) assigned to one of three dietary treatment groups measure coefficient apparent ileal (CAID), total tract (CATTD) Dietary treatments during experimental period were as follows: (1) high-P (HP) diet containing 3·4...

10.1017/s0007114514001494 article EN British Journal Of Nutrition 2014-07-07

The crustacean shells-derived polysaccharide chitosan has received much attention for its anti-obesity potential. Dietary supplementation of been linked with reductions in feed intake, suggesting a potential link between and appetite control. Hence the objective this experiment was to investigate suppressing prawn shell derived pig model. Pigs (70 ± 0.90 kg, 125 days age, SD 2.0) were fed either T1) basal diet or T2) plus 1000 ppm (n = 20 gilts per group) 63 days. parameter categories which...

10.1371/journal.pone.0149820 article EN cc-by PLoS ONE 2016-02-22

Abstract A 2 × 3 factorial design experiment was conducted to examine the effects of reducing dietary crude protein (CP) concentration and/or supplementation with zinc oxide (ZnO) or laminarin on faecal scores (FS) and large intestinal microbiota post‐weaning (PW). One hundred forty‐four pigs were assigned (T1) 21% standard CP diet (SCP); (T2) SCP + ZnO (SCP ZnO); (T3) LAM); (T4) 18% low (LCP); (T5) LCP (LCP (T6) LAM; n = 8 replicates/treatment). The had no effect FS ( p > .05), it...

10.1111/jpn.13428 article EN Journal of Animal Physiology and Animal Nutrition 2020-08-06

The objective of this study was to examine the effects feeding laminarin (LAM) and fucoidan (FUC) enriched seaweed extracts up d35 post-weaning on measures animal performance, intestinal microbial transcriptome profiles. 75 pigs were assigned one three groups: (1) basal diet; (2) diet + 250 ppm fucoidan; (3) 300 with 7 replicates per treatment group. Measures performance collected weekly animals sacrificed for sampling gastrointestinal tissue digesta. Animal similar between group groups...

10.3390/md19040183 article EN cc-by Marine Drugs 2021-03-26

This study examined the effects of dietary supplementation with laminarin or chitosan on colonic health in pigs challenged dextran sodium sulphate (DSS). Weaned were assigned to: (1) a basal diet (n = 22); (2) + 10); and (3) 10). On d35, group was split, creating four groups: (control); DSS; (4) DSS. From d39–42, orally d44, tissue/digesta samples collected. The DSS had reduced growth, higher pathology score an increased expression MMP1, IL13 IL23 compared controls (p < 0.05); these...

10.3390/md18050262 article EN cc-by Marine Drugs 2020-05-16

While feed efficiency (FE) is a trait of great economic importance to the pig industry, influence intestinal microbiome in determining FE not well understood. The objective this experiment was determine relative and farm birth on colonic microbiome. Animals divergent residual intake (RFI) were sourced from two geographically distinct locations (farms A + B) Ireland. 8 most efficient (low RFI (LRFI)) least (high RFI, (HRFI)) pigs 12 LRFI HRFI B sacrificed. Colonic digesta collected for...

10.1017/s1751731120001500 article EN cc-by-nc-nd animal 2020-01-01

This study was conducted to examine the effects of varying selenium (Se) inclusion levels, in form Se-enriched mushroom powder (SeMP) and selenite, on post-weaning growth performance (Period 1; day 1−21), intestinal health antioxidant capacity 2; 21−39). Weaned pigs were blocked according live weight, sex litter origin randomly assigned following experimental groups: basal (basal + selenite (0.3 ppm Se)); ZnO 0.15 SeMP (0.15 0.3 Se)) 0.6 SeMP/Sel Se) (Sel) with eight replicates/experimental...

10.3390/ani12121503 article EN cc-by Animals 2022-06-09

The objective of this study was to compare the molecular, physiological and microbial effects mushroom powder (MP), vitamin D2 enriched (MPD2) zinc oxide (ZnO) in pigs post-weaning. Pigs (four pigs/pen; 12 pens/treatment) were assigned to: (1) basal diet (control), (2) + ZnO, (3) MP (2 g/kg feed) (4) MPD2 feed). Zinc supplementation improved feed intake (p < 0.001); increased caecal abundance Lactobacillus 0.05); villus height 0.05) duodenum, jejunum ileum; expression chemokine interleukin 8...

10.3390/ani11123603 article EN cc-by Animals 2021-12-20

This study examines the effects of increasing dietary inclusion levels fucoidan, from a 44% fucoidan extract on growth performance and intestinal health pigs post-weaning (PW). Seventy-two newly weaned (8.4 kg (SD 1.06)) were assigned to: (T1) basal diet (BD); (T2) BD + 125 ppm fucoidan; (T3) 250 (8 pens/treatment). The appropriate quantity was included to achieve these levels. Faecal scores recorded daily. On d15 PW, samples collected tract 1 pig/pen groups. Pigs supplemented with had...

10.3390/md17120680 article EN cc-by Marine Drugs 2019-11-30
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