A5039268974- Extracellular vesicles in disease
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Cellular Mechanics and Interactions
- 3D Printing in Biomedical Research
- Circular RNAs in diseases
- Immune cells in cancer
- Cell Adhesion Molecules Research
- Microtubule and mitosis dynamics
- Biocrusts and Microbial Ecology
- Nanoplatforms for cancer theranostics
- Cancer Immunotherapy and Biomarkers
Turku Centre for Computer Science
2022-2025
University of Turku
2022-2025
Åbo Akademi University
2022-2025
Inserm
2018-2021
Institut Curie
2018-2021
Université Paris Sciences et Lettres
2018-2021
Abstract Despite their roles in intercellular communications, the different populations of extracellular vesicles (EVs) and secretion mechanisms are not fully characterized: how to what extent EVs form as intraluminal endocytic compartments (exosomes), or at plasma membrane (PM) (ectosomes) remains unclear. Here we follow intracellular trafficking EV markers CD9 CD63 from endoplasmic reticulum residency compartment, respectively PM late endosomes. We observe transient co-localization both...
Abstract During tumorigenesis, the extracellular matrix (ECM), which constitutes structural scaffold of tissues, is profoundly remodeled. While impact such remodeling on tumor growth and invasion has been extensively investigated, much less known consequences ECM infiltration by immune cells. By combining tissue imaging machine-learning, we here show that localization T lymphocytes neutrophils, orchestrate antitumor responses, can be predicted defined topographical features fibrillar...
ABSTRACT Despite their important and multiple roles in intercellular communications, the different populations of extracellular vesicles (EVs) secretion mechanisms are not fully characterized yet. In particular, how to what extent EVs form either as intraluminal endocytic compartments (exosomes), or at plasma membrane (ectosomes) remains unclear. We followed HeLa cells intracellular trafficking EV markers CD9 CD63 from endoplasmic reticulum residency compartment identified transient...