Objective In the present study, we aimed to determine whether pregravid obesity independently predicts increased risks of perinatal complications following in vitro fertilization (IVF) and weight loss goals reduce risk poor pregnancy outcomes. Design Retrospective cohort study. Population All pregnancies after first fresh IVF cycle from January 2014 December 2016 Reproductive Center affiliated Shandong University were reviewed. A total 3,962 eligible singleton births stratified into cohorts...

ABSTRACT Objective To assess the performance of a standardized first‐trimester ultrasound screening strategy for fetal congenital heart disease (CHD). Methods This was large retrospective study involving 74 839 consecutive mixed‐risk pregnancies (77 396 fetuses). Routine scans at 11 + 0 to 13 6 weeks' gestation were performed in single center from January 2015 June 2023. All fetuses examined using predefined scanning with adjustment imaging parameters, which included assessment heart. The...

Expanded criteria donors (ECD) have the potential to greatly increase donor organ pool but pose a higher risk of delayed graft function (DGF) post-transplantation. Uridine diphosphate-glucose (UDP-Glc) plays significant role in extracellular signaling related tissue damage and retains stability for detection. Donor urinary UDP-Glc level may be an appropriate effective biomarker predicting DGF. Recipients who underwent successful kidney transplantation, with corresponding collection urine...

To analyze obstetric complications associated with aplastic anemia (AA) among pregnant women and the underlying factors.A retrospective analysis of 60 pregnancies AA. Thirty four these patients were grouped as complicated group having rest 26 without control group. Comparative was conducted to access related risk factors, which may affect maternal fetal complications.The major in this study premature labor, gestational diabetes, pre-eclampsia, acute heart failure, postpartum hemorrhage,...

To investigate the clinical characteristics, management, maternal and fetal outcomes in pregnant patients with myelodysplastic syndrome (MDS).A retrospective analysis was conducted on 25 women MDS between June 1998 January 2013. The data were summarized. These divided into poor outcome group control group, regression to find risk factors for outcomes.Five developed premature birth, five postpartum hemorrhage, one patient acute cardiac failure cerebral infarction. Twenty out of underwent...

Objective: To investigate the predictive value of decline in serum estradiol on second day after oocyte retrieval outcomes vitro fertilization (IVF) or intra-cytoplasmic sperm injection and embryo transfer (ICSI-ET) among high ovarian responders.Design: Retrospective single-center cohort study.Setting: Tertiary-care, university-affiliated teaching hospital.Patients Women aged 20–45 years undergoing assisted reproduction treatment from June 2014 to December 2015.Interventions: A total 980...

To establish the gestational age-specific reference ranges for thyroid-related indicators of pregnant women in our hospital, especially serum thyroid stimulating hormone (TSH) first trimester.A total 548 trimester were collected Peking University First Hospital from June 2013 to April 2014. Among them, 254 with single fetus who conformed National Academy Clinical Biochemistry criteria, without adverse pregnancy outcomes and obstetric complications, enrolled current study. their own...

Serum human chorionic gonadotrophin (hCG) is higher in twin than that singleton pregnancies. As hCG stimulates the thyroid to produce more free thyroxine (FT4), which may lead decreased thyroid-stimulating hormone (TSH) levels, reference ranges of thyroid-related indicators differ between and pregnancies first trimester. This study aimed establish for early compare them with pregnancies.Data 820 twin-pregnant women were extracted from established database all pregnant who delivered at Peking...

To track and analyze two false positive cases from non-invasive prenatal testing for potential fetal aneuploidy.The cases, respectively reported to have XO (+++) T18 (1/20) XO(+), were analyzed with conventional karyotyping, fluorescence in situ hybridization (FISH) massively parallel genomic sequencing (MPS).The first fetus, who was suspected XO(+++), verified super female syndrome (47,XXX/46,XX) due confined placental mosaicism by karyotyping of amniotic fluid cells, FISH analysis placenta...

This study investigated the mediating role of maladaptive cognitive emotion regulation strategies in relationship between alexithymia and self-perceived aging among older adults.

BACKGROUND As the population ages, comorbidities among elderly patients are becoming a significant problem, due to associated risks and mortality. Medication adherence is crucial for controlling chronic diseases improving patient outcomes; therefore, it important understand medication hospitalized patients. MATERIAL AND METHODS A cross-sectional study was conducted from June 2023 April 2024 in 2 tertiary hospitals Wuhu City, Anhui Province, China. Patients were divided into age groups: 45 60...

Objective To investigate the current status of screening and management thyroid diseases during pregnancy, to provide evidence for further improvement clinical management. Methods Clinical data 5 981 pregnant women who delivered at Peking University First Hospital between September 1, 2013 30, 2014 were analyzed retrospectively. Their average age was (30±4) years (18-47 years) gestational week (39.2±1.6) weeks (25.5-42.0 weeks). The reference range stimulating hormone (TSH) 0.1-2.5...

Objective To investigate the appropriate screening method for thyroid diseases during early pregnancy. Methods We collected information of 4 044 pregnant women who attended to Department Obstetrics and Gynecology Peking University First Hospital from September 1, 2013 30, 2014 antenatal care underwent one step in first trimester, which meant blood test stimulating hormone(TSH), free thyroxine(FT4) peroxidase antibody(TPOAb) at same time. Simulation analysis was performed on these with...

Objective: To investigate the effect of blood pressure (BP) control level on perinatal outcomes in women with mild-moderate gestational hypertension (GHp). Methods: Totally, 344 diagnosed initially as GHp who delivered Peking University Third Hospital from January 2012 to December 2016 were recruited. They divided into four groups according stabilized BP during pregnancy. (1) Group A: BP<130/80 mmHg (1 mmHg=0.133 kPa) ; (2) B: (130-139) / (80-89) mmHg; (3) C: (140-149) (90-99) (4) D:...

Objective: To summarize the clinical outcome of abnormal prokaryotic embryos [0PN (non-pronuclear), 1PN (one-pronuclear)] transfer for reference in work. Methods: collect data infertility patients who received vitro fertilization/intracytoplasmic sperm microinjection-embryo from January 1, 2013 to December 31, 2018 at reproductive center Beijing Chaoyang Hospital Affiliated Capital Medical University, and retrospectively analyze pregnancy cases embryo 0PN sources. Results: Forty-seven were...

Objective To analyze the maternal and fetal outcomes of pregnancies complicated by aplastic anemia (AA) to investigate underlying risk factors. Methods In this retrospective case control study, we retrieved medical records 85 singleton gravidas with AA (AA group) who were admitted Peking University People's Hospital from January 2003 2016, another 340 (case∶control=1∶4) without blood system or immune diseases gave birth at same period selected as group. Differences in general...

Objective: This study was to investigate the perioperative safety of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) for pseudomyxoma peritonei (PMP), and analyze risk factors serious adverse events (SAEs). Methods: The occurrences SAEs were retrospectively analyzed in 254 PMP patients treated with CRS HIPEC. Univariate multivariate analysis performed identify independent factors. Results: Among 272 HIPEC procedures patients, a total 93 (34.2%) occurred,...

The study was intended to explore the risk factors of gestational diabetes mellitus (GDM) and their influence on perinatal outcomes through deep neural network (DNN)-based Doppler color ultrasound (B-mode ultrasound) images. Specifically, 75 women with GDM were selected as experimental group, healthy pregnant control (Ctrl) group. DNN uses unsupervised method pretrain layer by then supervised accumulate parameters each layer, which can obtain good performance. In this study, analyzed...