A5027327396- Nanoparticles: synthesis and applications
- Medicinal Plants and Neuroprotection
- Immune cells in cancer
- Virus-based gene therapy research
- Natural product bioactivities and synthesis
- Viral Infectious Diseases and Gene Expression in Insects
- Seaweed-derived Bioactive Compounds
- Endoplasmic Reticulum Stress and Disease
- Bioactive natural compounds
- Cell death mechanisms and regulation
- Tannin, Tannase and Anticancer Activities
- Genomics, phytochemicals, and oxidative stress
- Cancer Cells and Metastasis
- Natural Compounds in Disease Treatment
- Autophagy in Disease and Therapy
- Cell Adhesion Molecules Research
- Medicinal Plant Research
- Inflammatory mediators and NSAID effects
- Graphene and Nanomaterials Applications
- Nanomaterials for catalytic reactions
- Herpesvirus Infections and Treatments
- Chemistry and Chemical Engineering
- Curcumin's Biomedical Applications
- Phytochemistry and Biological Activities
- CAR-T cell therapy research
Pusan National University
2020-2021
Pukyong National University
2016-2020
Government of the Republic of Korea
2017
Ecofriendly procedure for silver–silver chloride nanoparticle synthesis with different reaction parameters tested.
Advancements in metal nanoparticle synthesis using plant extracts and their anticancer activity have received significant attention recent years. The green approach for the of gold nanoparticles (AuNPs) leaf extract Sasa borealis is reported this study. Synthesis AuNPs was performed at 50 °C, formation observed after 20 min incubation. confirmed by UV-visible spectrum peak 542 nm. synthesized were oval, spherical with sizes around 10-30 nm transmission electron microscope. Energy dispersive...
Aster incisus is a common flower found in almost all regions of South Korea. In the current study, we investigated potential antioxidant and anti-inflammatory properties methanol extract LPS-stimulated RAW 264.7 cells. We analyzed phytochemicals contained by GC-MS. GC-MS results showed that contains 9 known compounds. Later on, DPPH assay, WST-1 nitric oxide (NO) Western blot, RT-PCR were conducted to investigate effects extract. Our assay revealed did not affect viability tested cell lines...
Tumor microenvironment components dictate the growth and progression of various cancers. Tumor-associated macrophages are most predominant cells in TME play a major role cancer invasiveness. Gastric is one common cancers Asia, recently, cases resistance to fluorouracil treatment have been reported. In this study, we investigated alternatively activated AGS gastric fluorouracil. THP-1 were polarized using recombinant human IL-4, then cocultured with treated Cell viability, Western blot,...
In this study, we investigated the effect of different extraction techniques for recovery bioactive secondary metabolites from Aspilia africana (A. africana). Subcritical water (SWE) at temperatures (SWE140, SWE160, SWE180), and a combination heating agitation (HA) were compared with conventional solvent using ethanol (80%, soxhlet). The extracts characterized total phenolic contents (TPC), Total flavonoid (TFC), compounds HPLC-UV–VIS. antioxidant activity by DPPH assay anticancer against...
In recent decades, various bioactive compounds from plants have been investigated for their potential use in the treatment of diseases humans. Aster incisus extract (AIE) is a common plant that mostly found Asia. It has traditionally used medicinal purposes South Korea. this study, we evaluated anticancer effects methanolic normal human cell line (HaCaT keratinocytes) and 4 different types cancer lines (A549, lung cancer; Hep3B, liver MDA‑MB‑231, breast AGS, gastric cancer). The HaCaT, A549,...
Viral replication of thymidine kinase deleted (tk−) vaccinia virus (VV) is attenuated in resting normal cells, enabling cancer selectivity, however, potency VV-tk− appears to be diminished cells. Previously, we found that wild-type herpes simplex (HSV)-tk (HSV-tk) disappeared most the recombinant VV after multiple screenings, and only a few containing naturally mutated HSV-tk remained stable. In this study, VV-tk western reserve (WR) was replaced by A167Y (HSV-tk418m), alter nucleoside...
Aspilia africana C. D. Adams (A. africana) is used in African folk medicine as a wound healing remedy. In this study, the potential anti-inflammatory effects of A. were investigated lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. The cytotoxicity was assessed RAW264.7, human embryonic kidney 293, and HaCaT cells using WST-1 assay. results indicated that concentrations up to 400 μg/mL safe for all cell lines studied. Further analyses, such nitric oxide (NO) assay, quantitative...