A5075452368- Synthesis and biological activity
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Seaweed-derived Bioactive Compounds
- Synthesis and Characterization of Heterocyclic Compounds
- Parkinson's Disease Mechanisms and Treatments
- Phytochemicals and Antioxidant Activities
- Treatment of Major Depression
- Protein Hydrolysis and Bioactive Peptides
- Aquaculture Nutrition and Growth
- Quinazolinone synthesis and applications
- Echinoderm biology and ecology
- Marine Sponges and Natural Products
- Multicomponent Synthesis of Heterocycles
- Pain Mechanisms and Treatments
- Synthesis of Organic Compounds
- Free Radicals and Antioxidants
- Nerve injury and regeneration
- Genomics, phytochemicals, and oxidative stress
- Nuclear Receptors and Signaling
- Natural Antidiabetic Agents Studies
- Pharmacological Effects of Natural Compounds
- Pharmaceutical Practices and Patient Outcomes
- Nanoparticles: synthesis and applications
- Neurological diseases and metabolism
Birla Institute of Technology and Science, Pilani
2013-2016
Indian Institute of Chemical Biology
2015
Amrita Vishwa Vidyapeetham
2011-2013
Aims Community College
2011
Abstract L‐3,4‐dihydroxyphenylalanine (L‐DOPA) reduces symptoms of P arkinson's disease ( PD ), but suffers from serious side effects on long‐term use. Melatonin (10–30 mg/kg, 6 doses at 10 hr intervals) was investigated to potentiate L ‐ DOPA therapeutic in 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine MPTP )‐induced parkinsonism mice. Striatal tyrosine hydroxylase TH ) immunoreactivity, , and phosphorylated ser 40 (p‐ protein levels were assayed 7th day. Nigral ‐positive neurons stereology...
The characterization and classification of smokeless tobacco products has been a continuously evolving process. This is based on number different parameters like nicotine content, moisture amount heavy metals, pH, in vitro cytotoxicity assays. Their contexts often vary between countries, research institutions, legal requirements. categorisation these quite challenging due to the diffused sample sizes, diverse array branded offer, absence centralized manufacturing facility. study aims at...
Introduction: Over the past decade, herbal and ayurvedic drugs have become a subject of world importance, with both medicinal economical implications. The relatively lower incidence adverse reactions to plant preparations compared modern pharmaceuticals is encouraging consuming public national health care institutions consider medicines as alternatives synthetic [1, 2, 3, 4] . Various crude extracts Mirabilis jalapa Linn family Nyctaginaceae has been widely used in traditional medicine....
A novel series of Quinazolines were synthesised by cyclisation reaction Anthranilic acid with urea to get 2,4 di hydroxy quinazoline (2) intermediate, which further treated POCl3 chloro (3), was Thio-morpholine (4) for 3 hrs compounds (5), are reacted aqueous ammonia compound(6), reacts different boronic acids 7(a-j) using Chan-Lam coupling conditions Target Novel Quinazoline derivatives (8a-8j). The structures new confirmed IR and 1H NMR 13C spectral data. Anti-bacterial anti-fungal...
A Novel Series of Compounds were synthesized by Condensation reaction Carbazole aldehyde with Substituted Acetophenone derivatives 4 (a-d) in presence alcoholic Sodium hydroxide Solution to get Chalcone Intermediates 5 (a-d), which further treated hydroxyl amine hydrochloride Pyridine Iso Oxazoline Derivatives 6 (a-d). The latter refluxed Primary amines and formaldehyde for 8–10 hrs Mannich bases. Structures new compounds confirmed IR 1H NMR 13C Spectral Data. Anti-bacterial Anti-fungal...
Depression is among the common psychiatric disorders, therefore pathways and pathogenesis associated with depression required to be studied. In few years, role of 5-hydroxytryptamine-1A/B (5-HT 1A/B ) receptors in depressive disorders have been revealed. Both preclinical clinical studies reported that potential agonist antagonist at 5-HT significant modulatory effects depression. However, collective details regarding involvement molecular lacking. Thus, present review evidence link between...