Laura Murphy

ORCID: 0000-0002-9614-3000
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About
Contact & Profiles
Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Arrhythmias and Treatments
  • Sepsis Diagnosis and Treatment
  • Antifungal resistance and susceptibility
  • Musculoskeletal pain and rehabilitation
  • Acute Kidney Injury Research
  • Mechanical Circulatory Support Devices
  • Heart Failure Treatment and Management
  • Fungal Infections and Studies
  • Cardiac pacing and defibrillation studies
  • Respiratory Support and Mechanisms
  • Nail Diseases and Treatments
  • Myofascial pain diagnosis and treatment
  • Radiology practices and education
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cardiac electrophysiology and arrhythmias
  • Myasthenia Gravis and Thymoma
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Cardiac Arrest and Resuscitation
  • Sarcoidosis and Beryllium Toxicity Research
  • Parathyroid Disorders and Treatments
  • Intensive Care Unit Cognitive Disorders
  • Renal function and acid-base balance
  • Infective Endocarditis Diagnosis and Management

Vanderbilt University
2017-2021

Vanderbilt University Medical Center
2020

University of Toledo Medical Center
2016-2018

Austin Health
2015

Boston University
2000

Boston Medical Center
2000

Abstract Introduction Intensive care unit-acquired weakness (ICU-AW) is a significant problem. There currently widespread variability in the methods used for manual muscle testing and handgrip dynamometry (HGD) to diagnose ICU-AW. This study was conducted two parts. The aims of this were: determine inter-rater reliability agreement strength using both isometric through-range techniques Medical Research Council sum score new four-point scale, examine validity HGD cutoff diagnosis ICU-AW...

10.1186/s13054-015-0780-5 article EN cc-by Critical Care 2015-02-09

Disruption of the endothelial glycocalyx contributes to acute lung injury in experimental sepsis but has not been well studied humans. To study degradation sepsis-induced ARDS, we measured plasma levels syndecan-1, a marker for degradation.The present is retrospective observational 262 ventilated medical ICU patients at risk ARDS due severe and APACHE II ≥ 25. Plasma syndecan-1 was enrollment. Primary analysis focused on association between development other organ dysfunction (Brussels...

10.1186/s13613-017-0325-y article EN cc-by Annals of Intensive Care 2017-10-06

This study seeks to evaluate the association between acute kidney injury (AKI), fluid overload (FO), and mortality in children supported with extracorporeal membrane oxygenation (ECMO) for refractory respiratory failure. retrospective observational cohort was performed at six tertiary care children's hospital intensive units, studying 424 patients < 18 years of age ECMO ≥ 24 hours a indication from January 1, 2007, December 31, 2011. In multivariate analysis, FO level initiation not...

10.1097/mat.0000000000001000 article EN ASAIO Journal 2019-05-02

10.1016/j.ajem.2020.05.115 article EN The American Journal of Emergency Medicine 2020-06-06

Acute purulent bacterial pericarditis is of rare occurrence in this modern antibiotic era. Primary involvement the pericardium without evidence underlying infection elsewhere even rarer. It a rapidly progressive with high mortality. We present an extremely case acute immunocompetent adult patient no chronic medical conditions.A 33-year-old previously healthy white man presented complaints chest pain and dyspnea. He was diagnosed as having discharged home on indomethacin. Over period 2 weeks,...

10.1186/s13256-018-1570-x article EN cc-by Journal of Medical Case Reports 2018-01-31

10.1016/s0002-9149(00)00870-5 article EN The American Journal of Cardiology 2000-07-01

Background Heart failure (HF) is a common complication to atrial fibrillation (AF), leading rehospitalization and death. Early identification of patients with AF at risk for HF might improve outcomes. We aimed derive score predict 1-year new-onset after an emergency department (ED) visit AF. Methods Results The RE-LY (Randomized Evaluation Long-Term Anticoagulant Therapy) registry enrolled presenting ED in 47 countries, followed them year. end point was hospitalization and/or Among 15 400...

10.1161/jaha.120.017735 article EN cc-by-nc-nd Journal of the American Heart Association 2021-09-13

We evaluated the response of cardiac resynchronization therapy (CRT) in ischemic cardiomyopathy (ICMP) and non-ischemic (NICMP).We determined if cause cardiomyopathy, versus non-ischemic, affects CRT outcomes regard to New York Heart Association (NYHA) category ejection fraction.We used a retrospective chart review for adult patients who underwent biventricular device placement between January 2005 July 2015 at university Toledo medication center as part their standard care.NYHA fraction...

10.19102/icrm.2016.070704 article EN Journal of Innovations in Cardiac Rhythm Management 2016-07-20
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