Christopher Thomas

ORCID: 0000-0002-9630-8506
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About
Contact & Profiles
Research Areas
  • Pulmonary Hypertension Research and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Arrhythmias and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Colorectal Cancer Screening and Detection
  • Antibiotics Pharmacokinetics and Efficacy
  • Organ Transplantation Techniques and Outcomes
  • Poisoning and overdose treatments
  • Congenital Heart Disease Studies
  • Heart Failure Treatment and Management
  • Antimicrobial Resistance in Staphylococcus
  • Renal function and acid-base balance
  • Infection Control and Ventilation
  • Pharmaceutical studies and practices
  • Electrolyte and hormonal disorders
  • Sepsis Diagnosis and Treatment
  • Esophageal Cancer Research and Treatment
  • Atrial Fibrillation Management and Outcomes
  • Muscle and Compartmental Disorders
  • Central Venous Catheters and Hemodialysis
  • Medical History and Innovations
  • Infective Endocarditis Diagnosis and Management
  • Blood groups and transfusion
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Clinical Reasoning and Diagnostic Skills

Louisiana State University Health Sciences Center New Orleans
2018-2025

University of Chicago Medical Center
2024

Our Lady of the Lake Regional Medical Center
2024

Phoenix Children's Hospital
2015-2023

VA Pittsburgh Healthcare System
2020-2022

Stanford University
2019-2021

Indiana University Health
2011-2018

Riley Hospital for Children
2011-2018

Indiana University – Purdue University Indianapolis
2013-2018

Rhode Island Hospital
2017

To determine the efficacy and safety of labetalol for hypertensive crisis in children ≤ 24 months age.Retrospective chart review. Statistical analysis utilized variance continuous data, chi-square tests nominal linear regression.A 737-bed pediatric teaching institution.Twenty-seven patients age were treated with 37 intravenous infusions labetalol, nicardipine, or nitroprusside urgency.None.The primary end point consisted time to 20% reduction systolic blood pressure. Primary points measured...

10.1097/pcc.0b013e3181e328d8 article EN Pediatric Critical Care Medicine 2010-05-21

Objectives To determine the optimal vancomycin dosing regimen to achieve empirical goal trough concentrations in pediatric patients with congenital heart disease and examine impact of cardiopulmonary bypass on requirements. Methods Patients younger than 18 years admitted cardiovascular intensive care unit (CVICU) at our institution from October 1, 2012–December 31, 2014, who received least one dose vancomycin, were reviewed retrospectively. Included had a steady‐state concentration drawn...

10.1002/phar.2019 article EN Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy 2017-08-22

10.1152/ajplegacy.1952.172.1.83 article EN American Journal of Physiology-Legacy Content 1952-12-31

Objective To determine the incidence of supratherapeutic international normalized ratio (INR) values in patients initiated on warfarin pediatric intensive care unit after Fontan procedure. Design Retrospective chart review. Setting Pediatric a freestanding teaching hospital. Patients Thirty-two consecutive children with single ventricle physiology an initial conversion. All were postoperative period while unit. Outcome Measures Supratherapeutic INR values, interventions dosing to address or...

10.1111/chd.12151 article EN Congenital Heart Disease 2013-11-25

The implementation of a diuretic stewardship program in pediatric cardiovascular intensive care unit (ICU) is described.This retrospective study compared the use i.v. chlorothiazide and ethacrynic acid surgery patients before after program. All admitted to service were included. was educated on formal indications for specific agents, implemented January 1, 2013. Under program, indicated with sulfonamide allergy, considered appropriate receiving maximized loop doses. A detailed review...

10.2146/ajhp140532 article EN American Journal of Health-System Pharmacy 2015-05-29

BACKGROUND Pulmonary vein (PV) stenosis is a rare condition characterized by progressive luminal size reduction of one or more pulmonary veins (PVs), which can increase postcapillary pressure resulting in shortness breath, cough, hemoptysis, and hypertension (PH). The diagnosis PV requires high degree suspicion. but recognized complication catheter-based radiofrequency ablation (RFA) for atrial fibrillation (AF). CASE REPORT We present case 78-year-old man who underwent surgical MAZE...

10.12659/ajcr.924709 article EN American Journal of Case Reports 2020-07-15

The American Heart Association recently published an updated scientific statement on the management of infective endocarditis in childhood. recommendations included for vancomycin, aminoglycoside, and β-lactam dosing monitoring are based primarily expert opinion do not consider available evidence dose optimization pharmacokinetic pharmacodynamic principles pediatric patients. This is concerning because even when clinically necessary, some practitioners may be hesitant to deviate from...

10.1177/1060028016635660 article EN Annals of Pharmacotherapy 2016-02-25

Enoxaparin may be used to prevent central venous catheter-related thrombosis in patients with CHD. We aimed determine whether current enoxaparin dosing regimens effectively achieve anti-factor Xa concentrations within prophylactic goal ranges this patient population.We implemented a formal protocol at reducing children CHD January, 2016. Standard empiric were - for example, 0.75 mg/kg/dose every 12 hours <2 months of age and 0.5 ⩾2 range 0.25-0.49 IU/ml. Patients years who received had least...

10.1017/s1047951118000173 article EN Cardiology in the Young 2018-03-01

We report the case of a 5-years old child referred to pediatric clinic due prolonged history recurrent otitis. Initial immunologic investigation was normal but severe C3 complement deficiency detected by absence beta 2-globulin protein fraction using serum capillary electrophoresis. not in and total haemolytic activity decreased. His mother father had half plasma level heterozygous mutation gene. The diagnosis hereditary third component (C3) with compound gene made. This defect C3, described...

10.1684/abc.2009.0387 article EN Annales de biologie clinique 2009-11-01

( Int J Obstet Anesth . 2023;56:103930. doi: 10.1016/j.ijoa.2023.103930|) In the United States, specialized training in obstetric anesthesiology is linked to better patient outcomes and lower risks during childbirth. A consensus statement from 2015, endorsed by major medical bodies, advocates for concentrating high-risk services improve maternal health. The suggests specific staffing guidelines different levels of perinatal centers, emphasizing need anesthesiologists at advanced facilities...

10.1097/01.aoa.0001026480.13978.b4 article EN Obstetric Anesthesia Digest 2024-08-23

Abstract Background In August 2023 Our Lady of the Lake Regional Medical Center implemented a process for sepsis care based on novel diagnostic (IntelliSep) in Emergency Department (ED). As component our Sepsis Learning Health Program, we continually evaluate this process. Methods A nurse-driven protocol allows IntelliSep ordering with triage assessment. Dependent upon bed availability and assessment clinical stability by staff, patients may be referred to waiting room after blood draw. An...

10.1093/clinchem/hvae106.560 article EN Clinical Chemistry 2024-10-01

Drug- and toxin-induced pulmonary arterial hypertension (PAH) is an increasingly important sub-group of group 1 (PH). In the last 60 years, we have seen rise fall numerous prescription illicit agents that caused severe deadly outbreaks PAH. Currently, drugs toxins are classified into “possible” “definite” risk factors for While exact mechanisms pathogenesis drug- PAH currently unknown, novel clinical basic science studies beginning to unravel biologic genetic underpinnings responsible...

10.21542/gcsp.2019.19 article EN cc-by Global Cardiology Science and Practice 2020-02-09

We are experiencing declining reimbursements and rising costly overheads in American healthcare. The modern healthcare provider faces the challenge of balancing efficient with overload paperwork that is increasing burnout motivating doctors to early retirement. Using virtual assistants as a staffing alternative addresses needs many medical practices, regardless their size or location. This article explores role ability revolutionize delivery offers information on implementing assistant.

10.55834/halmj.6112629027 article EN Healthcare Administration Leadership & Management Journal 2024-10-28
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