- Hearing, Cochlea, Tinnitus, Genetics
- interferon and immune responses
- Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Vestibular and auditory disorders
- Cancer, Hypoxia, and Metabolism
- Head and Neck Cancer Studies
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cellular transport and secretion
XinHua Hospital
2024-2025
Shanghai Jiao Tong University
2020-2025
Shanghai Ninth People's Hospital
2020-2024
Adenoid hypertrophy is a common disorder of childhood, and has an unclear pathogenesis. At the beginning COVID-19 pandemic, there was significant reduction in incidence adenoid children under long-term home quarantine, providing rare research model to explore pathogenesis treatment targets adenoidal children. Before during quarantine period, adenoids that underwent surgery were detected using label-free proteomics. Differences protein expression analyzed Gene Ontology, Kyoto Encyclopedia...
Abstract The ribbon synapses of cochlear inner hair cells (IHCs) employ efficient vesicle resupply to enable fast and sustained release rates. However, the molecular mechanisms these physiological activities remain unelucidated. Previous studies showed that RAB‐specific GTPase‐activating protein TBC1D24 controls endosomal trafficking synaptic vesicles (SVs) in Drosophila mammalian neurons, mutations may lead non‐syndromic hearing loss or associated with DOORS syndrome humans. In this study,...