A5073432046- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Musculoskeletal pain and rehabilitation
- Cancer survivorship and care
- Colorectal and Anal Carcinomas
- Anorectal Disease Treatments and Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Spine and Intervertebral Disc Pathology
- Enhanced Recovery After Surgery
- Frailty in Older Adults
- Nutrition and Health in Aging
- Appendicitis Diagnosis and Management
- Colorectal Cancer Screening and Detection
- Prostate Cancer Diagnosis and Treatment
- Hernia repair and management
- Pelvic floor disorders treatments
- Atrial Fibrillation Management and Outcomes
- Delphi Technique in Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Occupational Health and Performance
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pelvic and Acetabular Injuries
- Surgical Simulation and Training
- COVID-19 and healthcare impacts
- Ovarian cancer diagnosis and treatment
Royal Prince Alfred Hospital
2017-2025
The University of Sydney
2016-2025
Cooperative Trials Group for Neuro-Oncology
2023-2024
Sydney Local Health District
2018-2024
Charité - Universitätsmedizin Berlin
2013-2023
Southampton General Hospital
2023
University of Southampton
2023
Humboldt-Universität zu Berlin
2022-2023
Freie Universität Berlin
2022-2023
Klinik für Schlafmedizin
2021
Pelvic exenteration (PE) is the preferred treatment available for selected patients diagnosed with locally advanced or recurrent cancer confined to pelvis. Currently, majority of literature reports only on short-term survival and quality-of-life (QoL) outcomes. The aim this prospective cohort study was describe long-term QoL outcomes following PE. This a consecutive undergoing PE from 1994 2016 at major teaching hospital in Sydney, Australia. From 2008, consenting were also included study....
Recently, the number of prehabilitation trials has increased significantly. The identification key research priorities is vital in guiding future directions. Thus, aim this collaborative study was to define for patients undergoing cancer surgery.The Delphi methodology implemented over three rounds surveys distributed experts from across multiple specialties, tumour streams and countries via a secure online platform. In first round, participants were asked provide baseline demographics...
Abstract Modern advances in medicine and technology have led to an increase robotic-assisted surgery (RAS) cases. However, concerns been raised about the potential environmental impact of RAS. Despite this, only limited quantitative evidence is currently available. Therefore, this study aims objectively quantify a multi-specialty RAS caseload at Australian public tertiary hospital. An analysis was performed amount waste produced on consecutive between August 2016 March 2023 major The weight...
To investigate a range of transient risk factors for an episode sudden-onset, acute low back pain (LBP).This case-crossover study recruited 999 subjects with new LBP between October 2011 and November 2012 from 300 primary care clinics in Sydney, Australia. Each participant was asked to report exposure 12 putative triggers over the 96 hours preceding onset pain. Conditional logistic regression used estimate odds ratios (ORs) expressing magnitude increased each trigger.Exposure physical...
Objective— Diabetes mellitus involves vascular inflammatory processes and is a main contributor to cardiovascular mortality. Notably, heightened levels of circulating tissue factor (TF) account for the increased thrombogenicity put those patients at risk thromboembolic events. Here, we sought investigate role micro-RNA (miR)–driven TF expression in diabetes mellitus. Approach Results— Plasma samples with were analyzed protein activity as well miR-126 before after optimization antidiabetic...
Introduction In order to prevent falls, older people should exercise for at least 2 h per week 6 months, with a strong focus on balance exercises. This article describes the design of randomised controlled trial evaluate effectiveness home-based programme delivered through tablet computer falls in people. Methods and analysis Participants aged 70 years or older, living community Sydney will be recruited randomly allocated an intervention control group. The consists tailored, training...
Abstract Background Pelvic exenteration (PE) provides a potentially curative option for advanced or recurrent malignancy confined to the pelvis. A clear (R0) resection margin is strongest prognostic factor predicting long-term survival, driving most technical advances in PE surgery. The aim of this cohort study was describe changing trends extent resection, postoperative complications, mortality and overall survival after Methods Consecutive patients who underwent pelvic at single...
To determine surgical, survival and quality of life outcomes across different tumour streams lessons learned over 28 years.Consecutive patients undergoing pelvic exenteration at a single, high volume, referral hospital, between 1994 2022 were included. Patients grouped according to their type presentation as follows, advanced primary rectal cancer, other malignancy, locally recurrent malignancy non-malignant indications. The main included, resection margins, postoperative morbidity,...
Although recurrence is common after an acute episode of low back pain, estimates rates vary widely and predictors remain largely unknown.The purposes the study were to determine 1-year incidence in participants who recovered from pain identify recurrence.The design was inception cohort nested a case-crossover study.For 12 months, 832 999 initially presented primary care within first 7 days followed. Of these participants, 469 (1 month free) index 6 weeks included this study. Recurrence...
Abstract Objective To establish the feasibility and acceptability of a preoperative exercise program, to obtain pilot data on likely difference in key surgical outcomes inform sample size calculation for full-scale trial. Design Pilot randomized controlled Setting Royal Prince Alfred Hospital, Sydney, Australia. Subjects We included patients undergoing elective pelvic exenteration or cytoreductive surgery aged 18 80 years, who presented participating gastrointestinal surgeon at least 2 weeks...
Abstract Background A barrier to the uptake of robotic-assisted surgery (RAS) continues be perceived high costs. lack detailed costing information has made it difficult for public hospitals in particular determine whether use technology is justified. This study aims provide a description patient episode costs and contribution RAS specific multiple specialties sector. Methods retrospective descriptive review all cases undertaken at large tertiary referral hospital Sydney, Australia from...