- Birth, Development, and Health
- Reproductive Physiology in Livestock
- Genetic and phenotypic traits in livestock
- Effects of Environmental Stressors on Livestock
- Adipose Tissue and Metabolism
- Reproductive Biology and Fertility
- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- Fatty Acid Research and Health
- Regulation of Appetite and Obesity
- Animal Behavior and Welfare Studies
- Ruminant Nutrition and Digestive Physiology
- Animal Nutrition and Physiology
- Livestock Management and Performance Improvement
- Ovarian function and disorders
- Animal health and immunology
- Adipokines, Inflammation, and Metabolic Diseases
- Milk Quality and Mastitis in Dairy Cows
- Child Nutrition and Water Access
- Sperm and Testicular Function
- Animal Disease Management and Epidemiology
- Obesity, Physical Activity, Diet
- Meat and Animal Product Quality
- Diet and metabolism studies
- Vector-Borne Animal Diseases
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria
2016-2025
Consejo Superior de Investigaciones Científicas
2022-2025
Centro Regional de Selección y Reproducción Animal
2012-2023
Universidade da Coruña
2019-2021
Hospital Universitario Puerta de Hierro Majadahonda
2014
The objective of the present study was to determine suitability a swine breed with leptin resistance and predisposition obesity (the Iberian pig) as model for studies on metabolic syndrome type 2 diabetes. Thus, six sows had ad libitum access food enriched saturated fat (SFAD group; consumption estimated be 4.5 kg/animal/day) whilst four females acted controls were fed kg/animal/day commercial maintenance diet. After three months differential feeding, SFAD animals developed central obesity,...
A high intramuscular fat content characterizes Wagyu (WY) cattle breed. Our objective was to compare beef from WY, WY-by-Angus, or Wangus (WN) steers with European, Angus-by-Charolais-Limousine crossbred (ACL), considering metabolic biomarkers pre-slaughtering and nutritional characteristics, including health-related indexes of the lipid fraction. The fattening system olein-rich diets no exercise restriction included 82 steers, 24 29 WN, ACL. slaughter ages weights were (median interquartile...
Pregnancy and lactation are challenging states that affect maternal lamb health. In Lacaune dairy sheep, we evaluated the impact of parity, pregnancy rank, body condition on weight ewes lambs in mid-pregnancy (75 ± 5 d), late (142 4d), postpartum (52 5d pp). Maternal age was associated with initial decreases, followed by increases, condition. After lambing, both mature maiden lost indices glucose, protein, lipid metabolism were within physiological values during pregnancy, but depended...
<h2>Abstract</h2> A blinded, negative controlled, randomized intervention study was undertaken to test the hypothesis that addition of meloxicam, a nonsteroidal anti-inflammatory drug, antimicrobial treatment mild moderate clinical mastitis would improve fertility and reduce risk removal from herd. Cows (n=509) 61 herds in 8 regions (sites) 6 European countries were enrolled. Following herd-owner diagnosis within first 120d lactation single gland, rectal temperature, milk appearance,...
The effects of undernutrition during pregnancy on prenatal and postnatal development the offspring were evaluated in sows with obesity/leptin resistance. Females fed, from day 35 onwards, a diet fulfilling either 100% (group control, n=10) or 50% nutritional requirements underfed, n=10). In control group, maternal body weight increased (P<0.05) while it decreased remained steady underfed group. At days 75 100 gestation, plasma triglycerides lower but urea levels higher restricted than...
Transfer of passive immunity (TPI) is key to achieving a good status in newborn calves. The traditional scientific approach examines risk factors for the failure TPI, but benefits an excellent transfer are well recognized, justifying closer examination specific influencing factors. However, there scarce information about conditions related which may differ from those avoiding failure. Therefore, objective this work was detect determining immunity. From April July 2022, 1,041 calves 108...
At high altitudes, hypoxia, oxidative stress or both compromise sheep fertility. In the present work, we tested relative effect of short- long-term exposure to altitude hypobaric hypoxia and on corpora luteal structure function. The growth dynamics lutea during estrous cycle were studied daily by ultrasonography in cycling that either native naïve high-altitude conditions supplemented not with antioxidant vitamins. Arterial venous blood samples simultaneously drawn for determination gases...
The present study aimed to determine, in a swine model of leptin resistance, the effects type and timing maternal malnutrition on growth patterns, adiposity metabolic features progeny when exposed an obesogenic diet during their juvenile development possible concomitant offspring sex. Thus, four groups were considered. A CONTROL group involved pigs born from sows fed with fulfilling daily maintenance requirements for pregnancy. treated females same but either 160% or 50% pregnancy entire...
Maternal energy restriction during pregnancy predisposes to metabolic alterations in the offspring. The present study was designed evaluate phenotypic and consequences following maternal undernutrition an obese pig model define potential role of hypothalamic gene expression programming effects. Iberian sows were fed a control or 50 % restricted diet for last two-thirds gestation. Newborns assessed body organ weights, hormonal status, genes implicated homeostasis, glucocorticoid function...
Hydroxytyrosol is a polyphenol with antioxidant, metabolism-regulatory, anti-inflammatory and immuno-modulatory properties. The present study aimed to determine whether supplementing the maternal diet hydroxytyrosol during pregnancy can improve pre- early post-natal developmental patterns metabolic traits of offspring. Experiment was performed in Iberian sows fed restricted order increase risk IUGR. Ten were treated daily 1.5 mg per kg feed between Day 35 (30% total gestational period) until...
The use of polyphenols is a promising strategy for preventing or alleviating intrauterine growth restriction (IUGR) because polyphenol supplementation increases plasma antioxidant capacity and improves oxidative stress at the feto-placental unit; which are recognized as main issues in IUGR. However, there scarcity experimental data on both realistic benefits potential hazards during gestation. Hence, we aimed to swine model IUGR pregnancy determine possible effects maternal with...
ABSTRACT The influence of estrus and double ovulations Holstein heifers on a 5d‐Co‐synch 72 h protocol during summer was explored. Cycling the 5d‐Co‐72 synchronisation were randomised to carry progesterone device (116) from day 0 5 or not (97), them 100 84 underwent fixed‐time artificial insemination (FTAI). Another 70 showed before first GnRH inseminated. Heifers pregnant 34% (33/97) without device, 44.0% (51/116) with 44.3% (31/70) inseminated after estrus. Pregnancy per (P/AI) tended be...
The present study investigated the effect of age at first lambing (AFL) on performance Lacaune sheep under intensive management conditions. Records from 3088 maiden one farm, for period 2005–2010, were classified into four experimental groups: group E (early) ewes with AFL ⩽390 d; M (middle) 391–450 L (late) 451–510 and A (aged) ⩾511 d. higher number lactations, lower yield/lactation yield/Day in Milk. Ewes up to 450 days old lambed 0·2 times more often had 0·25 lactations than L; addition,...
Maternal malnutrition during pregnancy, both deficiency and excess, induces changes in the intrauterine environment metabolic status of offspring, playing a key role growth, fitness/obesity appearance disorders postnatal life. There is increasing evidence that these effects may not be only limited to first generation descendants, offspring directly exposed challenges, but subsequent generations. This study evaluated, swine model obesity/leptin resistance, existence extent transgenerational...
The present study evaluated the effectiveness of sildenafil citrate (SC) to improve placental and fetal growth in a diet-induced rabbit model intrauterine restriction (IUGR). Pregnant rabbits were fed either ad libitum (Group C) or restricted 50% dietary requirements R) treated with SC SC). treatment improved development by increasing vascularity vessel hypertrophy decidua. assessment feto-placental haemodynamics showed higher resistance pulsatility indices at middle cerebral artery (MCA)...