The Type 1 family of growth factor receptors includes epidermal receptor (EGFR), c-erbB-2, c-erbB-3 and c-erbB-4. Overexpression the first two members is associated with poorer prognosis in patients breast carcinoma. In this study we examined expression c-erbB-4 protein using monoclonal antibody HFR-1. A total 127 consecutive cases primary operable invasive carcinoma presenting between 1975 1977 were studied. All managed by simple mastectomy or conservation surgery radiotherapy no adjuvant...

External auditory canal cholesteatoma (EACC) is a rare occurrence characterized by the keratinized mass of squamous epithelial cells in external ear canal, leading to bone erosion and potential damage surrounding structures. It's often misdiagnosed as otitis externa. Both conditions exhibit similar symptoms, which frequently result misdiagnosis clinicians. Though it more common older adults, EACC can occur younger patients, demonstrated case an 18-year-old male. Insufficient diagnosis delays...

Epistaxis is commonly encountered in otorhinolaryngologic practice. However, severe and recurrent epistaxis rarely seen, especially that originating from a pseudoaneurysm of the intracavernous internal carotid artery (ICA). We herein present case 32-year-old man who was involved motor vehicle accident subsequently developed episodes profuse for next three months, which required blood transfusion nasal packing to control bleeding. Computed tomography angiography revealed large ICA measuring...

Introduction: The fundament of forensic science lies in identifying a body. morphological complexity the paranasal sinus (PNS), which varies greatly amongst individual, possess discriminatory value that potentially contributes to radiological identification. sphenoid bone represents keystone skull and forms part cranial vault. It is intimately associated with vital neurovascular structures. sinus, located within body bone, has variable morphology. septum's inconsistent position degree, as...

Abstract Objective: We report an extremely rare case of duplication the internal auditory canal associated with dysfunction both facial and vestibulocochlear nerves. also review literature regarding integrity nerves in such cases. Case report: A 34-year-old man presented unilateral, right-sided, sensorineural hearing loss nerve palsy since childhood. Facial function was observed to be House–Brackmann grade III. Computed tomography magnetic resonance imaging demonstrated ipsilateral...

Abstract Objective: To study the outcome of endonasal endoscopic surgery for adenoid cystic carcinoma sinonasal tract over a five-year follow-up period. Design: Retrospective analysis. Methods: Four consecutive patients with tract, who had undergone surgery, were reviewed regarding age at diagnosis, sex, primary site, tumour-node-metastasis staging, treatment modalities, histopathological findings, duration follow up, distant metastases and outcome. Results: All diagnosed an advanced stage...

Multiple myeloma (MM) is characterized by progressive proliferation of malignant plasma cells, usually initiating in the bone marrow. MM can affect any organ; a total 7 - 18% patients with demonstrate extramedullary involvement at diagnosis. Non-secretory multiple (NSMM) rare variant that accounts for 1 5% all cases myeloma. The disease absence monoclonal gammopathy serum and urine electrophoresis. Our case report highlights diagnostic challenge NSMM extensive young female patient who...

Magnetic resonance imaging (MRI) of the brain was performed to further characterise lesion.This lesion returned homogeneous hypointensity on T1-weighted images and hyperintensity T2-weighted

This study aimed to evaluate the association between cochlear nerve canal dimensions and semicircular abnormalities determine distribution of bony labyrinth anomalies in patients with stenosis.This was a retrospective which high-resolution computed tomography images paediatric severe-to-profound sensorineural hearing loss were reviewed. A diameter 1.5 mm or less axial plane classified as stenotic. Semicircular canals other morphology abnormality evaluated.Cochlear stenosis detected 65 out...

ABSTRACT Congenital neonatal pyriform aperture stenosis (CNPAS) is a rare but potentially lethal condition that causes respiratory distress. The characteristic narrowing of the along with other associated craniofacial dysmorphism diagnosed using cross-sectional imaging such as computed tomography (CT) and magnetic resonance imaging. CT scan choice for confirming characterizing CNPAS. Infants are obligate nasal breathers in first 5 months life. Hence, high degree clinical suspicion, prompt...

Cat scratch disease (CSD) is a benign condition caused by the inoculation of Bartonella henselae. The imaging findings are non-specific, and it difficult to diagnose via imaging. However, studies help exclude other differential diagnoses in diagnostic dilemmas. We encountered case 17-year-old adolescent who presented with painful neck swelling. CT showed multiple bilateral cervical lymphadenopathies triangular soft tissue mass at anterior mediastinum likely be thymic hyperplasia, which...

Skull base osteomyelitis is a not commonly encountered but potentially fatal consequence of untreated necrotizing otitis externa. Early recognition and appropriate treatment are crucial to prevent serious complications such as cranial nerve palsies, meningitis, intracranial abscess formation. The case reports presented in this study provide rich depiction the clinical presentation, diagnostic challenges, interventions employed. management skull improve patient outcomes.

Background: A centrally limited radiological pattern, marked by mucosal thickening in the central sinonasal cavity with relatively unaffected surrounding sinuses, has been linked to allergy chronic rhinosinusitis (CRS). However, a comparison between allergic and non-atopic CRS patients is lacking. The role of anatomical variations ostiomeatal complex also remains unclear. Methods: Adult rhinitis, asthma, eczema, positive tests were recruited. without atopic disease negative controls. CT...

is notorious for its intrinsic resistance to many commonly used antibiotics, making it a particularly challenging pathogen treat. It often causes severe opportunistic infections in immunocompromised and hospitalized patients. The potential this infection become fulminant with high mortality rates both adults children necessitates multidisciplinary approach. Prompt initiation of appropriate antibiotic therapy can be lifesaving. In case report, we present rare instance involving an...

We present the rare case of a 47-year-old woman with protracted primary hyperparathyroidism complicated by communicating hydrocephalus and cerebellar tonsillar herniation secondary to calvarial thickening.The parathyroid glands remained elusive, despite use advanced preoperative imaging modalities three neck explorations.The serum calcium was optimally controlled cinacalcet alfacalcidol.Awareness this complication is essential for early diagnosis prompt intervention prevent fatal posterior...

Schwannomas are a benign and rare entity that originates from Schwann cells. The majority of schwannomas found in the head neck regions usually involve intratemporal course facial nerve (FN). Isolated extratemporal intraparotid involvement is very rare. It challenging to diagnose schwannoma (PFNS) based on fine needle aspiration cytology (FNAC) preoperatively. We report case an masquerading as pleomorphic adenoma. diagnostic challenges imaging features along with its management discussed.