- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- Pediatric health and respiratory diseases
- Immunodeficiency and Autoimmune Disorders
- Allergic Rhinitis and Sensitization
- Chronic Lymphocytic Leukemia Research
- T-cell and B-cell Immunology
- Bioinformatics and Genomic Networks
- PI3K/AKT/mTOR signaling in cancer
- Infant Nutrition and Health
- RNA modifications and cancer
- Blood disorders and treatments
- Epigenetics and DNA Methylation
- Immunotherapy and Immune Responses
- Cancer-related molecular mechanisms research
- Diabetes and associated disorders
- Breastfeeding Practices and Influences
- Birth, Development, and Health
- Digestive system and related health
- Immune Cell Function and Interaction
- Metabolism, Diabetes, and Cancer
- Effects and risks of endocrine disrupting chemicals
University of Cyprus
2024
Sağlık Bilimleri Üniversitesi
2023
University of Kyrenia
2020-2022
Near East University
2018
Imperial College London
2012
Minor histocompatibility (H) Ags are classically described as self-peptides derived from intracellular proteins that expressed at the cell surface by MHC class I and II molecules induce T alloresponses. We have isolated three different populations a skin biopsy of patient suffering acute graft-versus-host disease following sex-mismatched HLA-identical bone marrow transplantation. The first population was: 1) CD4(+)/CD8(+) double-positive; 2) specific for an HLA I-restricted autosomal Ag; 3)...
The focus on repurposing readily available, well-known drugs for new, creative uses has grown recently. One such medication is metformin, a drug commonly used to manage diabetes, which shows favorable correlation between its use and lower cancer morbidity death. Numerous investigations clinical trials have been conducted evaluate the possible application of metformin as an anticancer in light this conclusion.
Objectives:We aimed to overview clinical characteristics of FPIAP with the results diagnostic tools like APT, SPT and fecal calprotectin levels factors associated tolerance development.Methods: All patients diagnosed at outpatient clinic between January 2015 2019 were enrolled retrospectively.Data about characteristics, APT or results, levels, suspected triggering foods, diet status obtained from hospital database program analyzed.Result: 169 infants F/M ratio 78/91 enrolled.The mean age...
Allergy immunotherapy (AIT) is currently the only disease-modifying treatment for allergic-respiratory diseases. Polysensitization may increase severity of current disease resulting in subsequent asthma development patients with allergic rhinitis. Due to absence general recommendations practical approach polysensitized patients, clinical management not standardized. The correlation between sensitizations and symptoms, elimination possible pollen cross-reactivities principles homologous...
Bisphenol A (BPA) is an industrial product, widely used in human consumed types of equipment that can be transmitted orally, by inhalation or through dermal absorption and detectable many body fluids including cord blood. correlation between BPA concentration maternal serum blood has been demonstrated previously, suggesting a possible transfer via the transplacental path.Our objective to determine impact level on cytokine responses.In this cross-sectional study, healthy pregnant women who...
Abstract Objective : Allergic asthma is the most frequently observed subtype of individuals with asthma. The effects serotonin plays in pathophysiology has not been clearly determined. Thus, this study aimed to investigate association between 5HTR2C gene rs 6318 G>C polymorphism and allergic pediatric patients Cyprus. Methods This included total number 177 118 control 59 (43 atopic 16 non-atopic patient). A skin prick test was performed for each patient confirm diagnosis evaluate status....
Background: The relationship between hypogammaglobulinemia and wheezing in childhood has been previously revealed. Objectives: study aimed to investigate co-morbid immune deficiency unresponsive asthmatic children, characterize the type of deficiency, determine any possible effect treatment on applied standard guideline asthma treatment. Methods: This was a prospective conducted January 2012 December 2014. A total 286 children whose serum immunoglobulin (Ig) levels had analyzed were...
Allergic asthma is the most frequently observed phenotype in majority of individuals with asthma. Whereas, non-atopic a no allergic sensitization. Serotonin (5-hydroxytryptamine, 5-HT) controls several physiological functions through different serotoninergic receptors (5-HTR). However, exact role serotonin pathophysiology has not been understood clearly. Importantly, genetic, epigenetic and environmental risk factors play crucial etiology Evidence suggests that psychosocial stress identified...