Franklin Espinosa

ORCID: 0000-0002-9905-1785
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About
Contact & Profiles
Research Areas
  • COVID-19 diagnosis using AI
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Bacterial biofilms and quorum sensing
  • Antibiotic Resistance in Bacteria
  • Vibrio bacteria research studies
  • COVID-19 and healthcare impacts
  • SARS-CoV-2 detection and testing
  • Research on Leishmaniasis Studies
  • Logistics and Transportation Systems
  • Cardiac, Anesthesia and Surgical Outcomes
  • Business, Innovation, and Economy
  • Quality and Supply Management
  • Trypanosoma species research and implications
  • Pain Management and Opioid Use
  • Pediatric Pain Management Techniques
  • Insect Pest Control Strategies

Universidad San Francisco de Quito
2024

Hospital Metropolitano
2023

Hospital General del Sur de Quito, IESS
2021

Hospital Vozandes
2020-2021

Instituto Ecuatoriano de Enfermedades Digestivas
2020-2021

Abstract SARS-CoV-2, the etiological agent of COVID-19 was first described in Wuhan December 2019 and has now spread globally. Ecuador second country South America to report confirmed cases. The case reported Quito, capital city Ecuador, a tourist who came from Netherlands presented symptoms on March 10th, 2020 (index case). In this work we used MinION platform (Oxford Nanopore Technologies) sequence metagenome bronchoalveolar lavage (BAL) reported, subsequently sequenced whole genome index...

10.1101/2020.06.11.20128330 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-06-14

Purpose: Discharge or follow up of confirmed coronavirus disease 2019 (COVID-19) cases depend on accurate interpretation RT-PCR. Currently, positive/negative interpretations are based amplification instead quantification cycle threshold (Ct) values, which could be used as proxies patient infectiousness. Here, we measured Ct values in hospitalized COVID-19 patients at different times and its implications diagnosis up. Patients Methods: Observational study between March 17th-May 12th, 2020...

10.2147/rmhp.s282962 article EN cc-by-nc Risk Management and Healthcare Policy 2021-03-01

The World Health Organization (WHO) declared coronavirus disease-2019 (COVID-19) a global pandemic on 11 March 2020. In Ecuador, the first case of COVID-19 was recorded 29 February Despite efforts to control its spread, SARS-CoV-2 overran Ecuadorian public health system, which became one most affected in Latin America 24 April Hospital General del Sur de Quito (HGSQ) had transition from general specific center short period time fulfill demand patients with respiratory afflictions. Here, we...

10.1371/journal.pone.0251295 article EN cc-by PLoS ONE 2021-05-17

Recent evidence suggests that Pseudomonas aeruginosa, a bacterium has the ability to cause deadly infections in hospitalized patients, could originate patient's own flora. We employed Oxford Nanopore platform obtain whole genome sequences (WGS) from clinical and rectal screen P. aeruginosa strains belonging 15 patients two hospitals. Our study found isolates were clonal, with some suggesting infecting strain was present intestine at time of admission, ruling out hospital acquisition. The use...

10.1016/j.infpip.2023.100331 article EN cc-by-nc-nd Infection Prevention in Practice 2023-12-11

Chagas disease, leishmaniasis, and malaria are major parasitic diseases disproportionately affecting the underprivileged population in developing nations. Finding new, alternative anti-parasitic compounds to treat these is crucial because of limited number options currently available, side effects they cause, need for long treatment courses, emergence drug-resistant parasites. Anti-microbial peptides (AMPs) derived from amphibian skin secretions small bioactive molecules capable lysing cell...

10.1128/spectrum.03339-23 article EN cc-by Microbiology Spectrum 2024-07-16

Abstract The World Health Organization (WHO) declared coronavirus disease-2019 (COVID-19) a global pandemic on March 11 th . In Ecuador, the first case of COVID-19 was recorded February 29 Despite efforts to control its spread, SARS-CoV-2 overrun Ecuadorian public health system which became one most affected in Latin America with 22,719 cases reported up April, 24 Public measures, including social distancing and lockdowns, were implemented at different times biggest cities country: Guayaquil...

10.1101/2020.07.25.20161661 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-07-27
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