A5050038065- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Bacteriophages and microbial interactions
- Herpesvirus Infections and Treatments
- Identification and Quantification in Food
- Plant Virus Research Studies
- Cervical Cancer and HPV Research
- Viral Infections and Vectors
- Salmonella and Campylobacter epidemiology
- Biosensors and Analytical Detection
- Adolescent Sexual and Reproductive Health
- Antimicrobial Peptides and Activities
Universitat Rovira i Virgili
2024-2025
University of the Philippines Diliman
2015-2024
Aptamer lateral flow assay (ALFA) for testing T. vaginalis (Tv) in cervicovaginal lavage (CVL).
Trichomoniasis, caused by Trichomonas vaginalis, is the leading nonviral sexually transmitted infection worldwide. We report selection of a DNA aptamer against T. vaginalis adhesion protein, AP65, using microtiter plate-based in vitro combinatorial chemistry process termed systematic evolution ligands exponential enrichment. The enriched library pool was sequenced next-generation sequencing, and several candidates with high affinity specificity were identified. highest had KD low nanomolar...
The flagellated protozoon Trichomonas vaginalis that parasitizes the urogenital tract of humans was reported to harbor double-stranded RNA (dsRNA) viruses. These viruses, identified as virus (TVV), belong genus Trichomonasvirus family Totiviridae. Four species, formally recognized by International Committee on Taxonomy Viruses (ICTV), have been and distinguished pairwise comparisons sequences genes coding for major capsid protein (CP) RNA-dependent polymerase (RdRp).Reverse transcription...
Trichomoniasis is the most prevalent curable, non-viral sexually transmitted infection (STI), with an estimated 156 million new infections in 2020. It can potentially result adverse birth outcomes as well infertility men, whilst it also increases risk of acquiring HIV and contracting other vaginal infections. mostly among women low-income countries especially Africa Americas. This STI caused by Trichomonas vaginalis (TV) a robust, cost-effective, sensitive, specific rapid diagnostic test...
Background. Metronidazole susceptibility and the presence of Trichomonas vaginalis virus (TVV) are phenotypes found to be significantly correlated with microsatellite-based genotypes T. vaginalis. These were assessed in isolates from select urban areas determine preliminary “type” Philippine vaginalis.
 Methods. Culture microscopy used detect vaginal swab samples collected women attending social hygiene clinics Metro Manila Angeles City, Philippines. Screening TVV on was performed using...