A5080693090- Intraoperative Neuromonitoring and Anesthetic Effects
- Spinal Fractures and Fixation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Spine and Intervertebral Disc Pathology
- Vestibular and auditory disorders
- Meningioma and schwannoma management
- Neuroscience and Neuropharmacology Research
- Surgical Simulation and Training
- Intracranial Aneurysms: Treatment and Complications
- Facial Nerve Paralysis Treatment and Research
- Retinal Development and Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Neural dynamics and brain function
- Motor Control and Adaptation
- Anesthesia and Pain Management
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Ophthalmology and Visual Impairment Studies
- Neuroscience and Neural Engineering
- Healthcare Technology and Patient Monitoring
- Action Observation and Synchronization
- Ear and Head Tumors
- Transcranial Magnetic Stimulation Studies
- Muscle activation and electromyography studies
- Scoliosis diagnosis and treatment
University of Washington
2015-2024
Harborview Medical Center
2019
American Physiological Society
2018
Child Neurology Associates
2013
Active Implants (United States)
2006
Northwestern University
2000-2004
University of Alabama at Birmingham
1988-1995
University of Hong Kong
1994-1995
Hong Kong University of Science and Technology
1994-1995
New York University Press
1988
Simultaneous single neuron and local field potential (LFP) recordings were made in arm-related areas of the cerebellar nuclei (CN) primary motor cortex (M1) two monkeys during a reaching button pressing task. Microstimulation focal sites CN caused short latency (median = 3.0 ms) increases discharge 25% 210 M1 neurons. Suppressive effects less common (13%) observed at longer latencies 9.9 ms). Stimulation also reciprocal facilitation suppression averages antagonist muscle electromyograms...
<h3>Importance</h3> Facial vascular anomalies are surgical challenges due to their vascularity and facial nerve distortion. To assist anomaly treatment, presurgical percutaneous stimulation recording of compound motor action potentials can be used map the branches. During surgery, continuous intraoperative end plate potential monitoring reduce injury. <h3>Objective</h3> investigate if preoperative mapping (FNM) is associated with injury risk safe approach options compared standard integrity...
Limb movement-related neurons in the cerebellar nuclei (CN) typically produce bursts of discharge association with movement. Consequently, given inhibitory nature Purkinje cell (PC) projection to CN, it is puzzling that only a minority PCs pause; majority burst. Some CN activity may be result excitation from collaterals mossy and climbing fiber projections cortex. The other input diffuse neuromodulatory, locus ceruleus raphe nuclei. To investigate role excitatory input, single units were...
Abstract Oscillations in the beta frequency range (β‐LFP) are widely distributed throughout motor system, modulated by dopaminergic medications, and locally generated subthalamic nucleus (STN) ventral intermediate of thalamus (VIM). We investigated feasibility recording intraoperative β‐LFP signals their descriptive summary statistics during surgeries for deep brain stimulation (DBS). from microelectrode stimulating lead were obtained STN Parkinson's patients, VIM patients with disease or...
Abstract A laminar analysis of the receptive field properties relay cells in binocular region tree shrew dorsal lateral geniculate nucleus (LGN) found three main subdivisions. Lamina 1 (receiving ipsilateral eye input) and lamina 2 (contralateral) comprise a pair layers that contain only ON‐center neurons. Laminae 4 5 (ipsilateral) with mostly OFF‐center (86%). 3 6 (both contralaterally innervated) also form distinct pair, although contains mixture ON‐centers (43%) or OFF‐centers (57%),...
Surgical treatment for symptomatic Chiari I malformation involves surgical decompression of the craniovertebral junction. Given proximity critical brainstem structures, intraoperative neuromonitoring (IONM) is employed safe in some institutions. However, IONM adds time and cost to operation, benefit patient has not been defined. diversity practices, there no evidence-based standard care regarding when use which modalities are most helpful. The purpose this study was review a single-surgeon...
EMG threshold testing as a guide to accurate screw placement was examined during posterior cervical spine instrumentation. The accuracy of placements compared with the surgeon blinded and unblinded thresholds.To determine utility in improving lateral mass pedicles cervical/upper thoracic spine.EMG lumbar is generally thought improve pedicle placements. These results may not generalize spine, where smaller pedicles, bicortical pilot holes, orientation screws away from midline result different...
The distribution and ultrastructure of neurons neuropil labeled by an antiserum to gamma-aminobutyric acid (GABA) were examined in the lateral geniculate nucleus (LGN) tree shrew (Tupaia belangeri). LGN this species segregates center type cell class into three distinct pairs laminae: a medial pair (laminae 1 2) containing ON-center cells, more (4, 5) OFF-center 2 laminae (3, 6) W-like cells. relationship between laminar segregation GABA immunoreactivity was investigated present study....