Karolina Kot

ORCID: 0000-0003-0051-2295
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About
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Research Areas
  • Legionella and Acanthamoeba research
  • Heme Oxygenase-1 and Carbon Monoxide
  • Heavy Metal Exposure and Toxicity
  • Mercury impact and mitigation studies
  • Trace Elements in Health
  • Acne and Rosacea Treatments and Effects
  • Hydrogen's biological and therapeutic effects
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Selenium in Biological Systems
  • Vibrio bacteria research studies
  • Ancient and Medieval Archaeology Studies
  • Historical and Archaeological Studies
  • Dermatological diseases and infestations
  • Heavy metals in environment
  • Medical and Biological Ozone Research
  • Yersinia bacterium, plague, ectoparasites research
  • Connexins and lens biology
  • Scientific Research and Studies
  • Bacterial Identification and Susceptibility Testing
  • Medieval European History and Architecture
  • Magnesium in Health and Disease
  • Eosinophilic Esophagitis
  • Diphtheria, Corynebacterium, and Tetanus
  • Nutrition and Health Studies
  • Osteoarthritis Treatment and Mechanisms

Pomeranian Medical University
2016-2025

Jagiellonian University
2023

Instytut Archeologii i Etnologii
2016

The aim of the study was to investigate relationships between concentrations macroelements (Ca), microelements (Cr, Cu, Fe, Mn, Mo, Ni, Sn, Sr, V, Zn) and heavy metals (Ag, Cd, Pb) in placenta, fetal membrane umbilical cord. ‪Furthermore, we examined these studied afterbirths maternal age, gestational placenta parameters (breadth, length, weight) newborn (length, weight Apgar score). This confirms previously reported Zn-Cd, Pb-Cd Ni-Pb interactions placenta. New types cord were also noted....

10.3390/ijerph16091615 article EN International Journal of Environmental Research and Public Health 2019-05-08

The aim of this study was to determine the subjective ocular symptoms in pre- and perimenopausal women infected with Demodex folliculorum D. brevis. Eyelashes were taken from aged 45 69 years (n = 253) younger 3 40 204) West Pomeranian Voivodeship located Poland. prevalence mites analyzed according age symptoms. spp. detected 75/253 (29.64%) 25/204 (12.25%) women. or brevis observed 72/252 (28.45%) 1/253 (0.4%) women, respectively, but coinfection noted 2/253 (0.79%) In young only detected....

10.3390/pathogens14030297 article EN cc-by Pathogens 2025-03-20

Little is known about the pathomechanism of pulmonary infections caused by Acanthamoeba sp. Therefore, aim this study was to determine whether may affect expression and activity cyclooxygenase-1 (COX-1) cyclooxygenase-2 (COX-2), resulting in altered levels their main products, prostaglandins (PGE2) thromboxane B2 (TXB2), lungs immunocompetent or immunosuppressed hosts. induced a strong COX-1 COX-2 proteins mice, which, however, did not result significant differences PGE2 TXB2. Our...

10.3390/ijms19010121 article EN International Journal of Molecular Sciences 2018-01-02

Abstract Blastocystis sp. is one of the most frequently detected protozoa during stool specimen examination. In last decade, studies about pathogenic potential have intensified. Additionally, treatment approaches against this parasite are still disputable. The study aimed to investigate in vitro activity substances natural origin two subtypes (ST) sp.—ST3 and ST7. Garlic turmeric extracts exhibited highest inhibitory effect relation ST3 viability. While horseradish were found be effective...

10.1186/s13099-024-00613-z article EN cc-by Gut Pathogens 2024-04-03

The aim of this study was to investigate the impact environmental factors on concentrations vanadium (V), chromium (Cr), and calcium (Ca) examine synergistic or antagonistic relationships between these metals, in cartilage (C), cortical bone (CB), spongy (SB) samples obtained following hip joint surgery patients with osteoarthritis NW Poland. We found significantly higher V Cr who consumed game meat also those prosthetic implants. Chromium levels were lower kidney diseases. greatest positive...

10.1155/2016/8340425 article EN BioMed Research International 2016-01-01

Acanthamoebiasis is most often found in patients with immune deficiency, infections facilitated by the intake of immunosuppressive drugs. The host response to Acanthamoeba spp. infection poorly understood. Thus, this study, we aimed examine course taking into account host's immunological status, including assessment hematological parameters, cytokine analysis, immunophenotypic changes spleen populations, and histological changes, which could help clarify some aspects acanthamoebiasis. In our...

10.1186/s13071-018-3108-x article EN cc-by Parasites & Vectors 2018-09-20

Essential and non-essential elements deficiencies may lead to various birth complications. The aim of this paper was determine calcium (Ca), copper (Cu), iron (Fe), potassium (K), magnesium (Mg), sodium (Na), phosphorus (P), (Pb), strontium (Sr), zinc (Zn) concentrations in maternal blood cord blood. Whole samples collected from pregnant women (n = 136) were analyzed for the concentration by spectrophotometric atomic absorption inductively coupled argon plasma (ICP-OES). results showed that...

10.3390/ijerph182312407 article EN International Journal of Environmental Research and Public Health 2021-11-25

Abstract Background Blastocystis spp. are considered pathogenic or commensal organisms, although the majority of researchers suggest that these neglected pathogens. The main aim this study was to determine prevalence and subtype distribution in pre- perimenopausal women, with respect socio-demographic (age place residence), epidemiological factors, as well drinking tap water, contact domestic animals, traveling abroad, health status, presence gastrointestinal symptoms. Additionally,...

10.1186/s12879-021-06815-z article EN cc-by BMC Infectious Diseases 2021-11-01

We aimed to determine the prevalence of Demodex spp. and bacterial infection in patients with blepharitis also investigate relationship between culturable microorganisms this study. The study included diagnosed (n = 128) volunteers without ocular problems 113). Eyelash sampling was performed by epilating eight lashes, which were then tested for using a light microscope. examination consisted assessing patient’s vision correction tonus both eyes careful anterior segment eyes. Bacterial...

10.3390/life13091827 article EN cc-by Life 2023-08-29

The pathological process occurring within the central nervous system (CNS) as a result of infection by Acanthamoeba spp. is not fully understood. Therefore, aim this study was to determine whether may affect levels matrix metalloproteinases (MMP-2,-9), their tissue inhibitors (TIMP-1,-3) and MMP-9/TIMP-1, MMP-2/TIMP-3 ratios in cerebral cortex hippocampus, relation host’s immunological status. Our results showed that can change MMP TIMP CNS be amenable targets for limiting amoebic...

10.3390/ijms19124128 article EN International Journal of Molecular Sciences 2018-12-19

Toll-like receptors (TLRs) play a key role in the innate immune response to numerous pathogens, including

10.1155/2019/1401894 article EN cc-by BioMed Research International 2019-06-12

The aim of this study was to determine the concentrations iron, nickel, molybdenum, and vanadium in knee joint. We also examined relationships between these metals joint influence varied factors on concentration Fe, Ni, Mo, V. trace elements is important, because are used alone combination diet supplements, they components biomaterials implanted medicine. materials, consisting spongy bone, cartilage, meniscus, anterior cruciate ligament (ACL), infrapatellar fat pad, were obtained from 34...

10.3390/ijerph17030813 article EN International Journal of Environmental Research and Public Health 2020-01-28

Abstract Background Acanthamoeba spp. are cosmopolitan protozoans that cause infections in the brain, as well extracerebral cornea, lungs and skin. Little is known about mechanisms of immunological response to these parasites organs which not their main biotope. Therefore, purpose this study was determine expression TLR2 TLR4 kidneys heart spp.-infected mice, with respect host’s status. Methods The mice were grouped into four groups: immunocompetent control mice; immunosuppressed infected...

10.1186/s13071-020-04351-4 article EN cc-by Parasites & Vectors 2020-09-21

Abstract This study examined the concentration of total mercury (THg) and selenium (Se), as well molar ratio Se:THg in hair samples terrestrial animals. THg Se concentrations were measured from raccoons ( Procyon lotor ) European wildcats Felis s. silvestris Germany Luxembourg. Median 0.369 0.273 mg kg −1 dry weight (dw), respectively. higher than (0.851 0.641 dw, respectively). Total Luxembourg was almost 5× that found Germany; however, similar. Thus, ~4× those Significant negative...

10.1007/s10646-019-02120-3 article EN cc-by Ecotoxicology 2019-11-16

The aim of the study was to assess phosphorus (P) concentration in structures knee joint-including tibial spongy bone, articular cartilage, meniscus, anterior cruciate ligament, and infrapatellar fat pad (Hoffa's pad)-of patients following joint replacement. also aimed influence selected biological environmental factors on P studied parts joint. Phosphorus determined using inductively coupled plasma-atomic emission spectrometry (ICP-AES). Statistically significant differences were found...

10.3390/ijerph16040525 article EN International Journal of Environmental Research and Public Health 2019-02-13

In times of widespread environmental pollution with heavy metals anthropogenic origin and the increasing dynamics this process, it is justified to collect as much data possible on concentration in terrestial mammals from unpolluted areas. The purpose research was present essential (chromium, copper, iron, manganese, molybdenum, zinc), probably (nickel, vanadium) non-esential element (cadmium, lead, silver, strontium, tin) liver, kidneys, muscles brain red fox (Vulpes vulpes) inhabiting...

10.1016/j.chemosphere.2023.138037 article EN cc-by Chemosphere 2023-01-31
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