A5063367539- Phytochemistry Medicinal Plant Applications
- Phytochemicals and Antioxidant Activities
- Natural Antidiabetic Agents Studies
- Pomegranate: compositions and health benefits
- Phytochemistry and Biological Activities
- Catalytic Processes in Materials Science
- Agricultural and Food Sciences
- Phytochemistry and biological activity of medicinal plants
- Hops Chemistry and Applications
- Vagus Nerve Stimulation Research
- Geography and Environmental Studies
- Botulinum Toxin and Related Neurological Disorders
- Skin Protection and Aging
- Seed Germination and Physiology
- Plant chemical constituents analysis
- Genomic variations and chromosomal abnormalities
- Antioxidant Activity and Oxidative Stress
- Allelopathy and phytotoxic interactions
- Phytochemistry and Bioactivity Studies
- Natural product bioactivities and synthesis
- Plant and Fungal Species Descriptions
- Cancer therapeutics and mechanisms
- Weed Control and Herbicide Applications
- Curcumin's Biomedical Applications
- Photodynamic Therapy Research Studies
Instituto Superior da Maia
2024
Universidade Estadual Paulista (Unesp)
2001-2023
Centro Universitário de Araraquara
2017
Universidade Federal do Espírito Santo
2014
Universidade Federal do Paraná
2013-2014
Instituto de Ciências Farmacêuticas
2013
Cuban Neuroscience Center
1992
Knowing that curcumin has low bioavailability when administered orally, and piperine bioenhancer activity by inhibition of hepatic intestinal biotransformation processes, the aim this study was to investigate antidiabetic antioxidant activities (90 mg/kg) (20 or 40 mg/kg), alone co-administered, incorporated in yoghurt, streptozotocin (STZ)-diabetic rats. The treatment for 45 days STZ-diabetic rats with curcumin-enriched yoghurt improved all parameters altered experimental model diabetes:...
There have been few studies on the pharmacological properties of Rhamnus sphaerosperma var. pubescens , a native Brazilian species popularly known as “fruto‐de‐pombo.” The aim this study was to investigate scavenging capacity emodin, physcion, and ethanolic crude extract against reactive oxygen nitrogen species, well their role plausible mechanisms in prompting cell death changes AKT phosphorylation after cervical (SiHa C33A) oral (HSC‐3) squamous carcinoma treatments. Emodin shown be best...
Photodynamic therapy (PDT) has proven to be a promising alternative current cancer treatments, especially if combined with conventional approaches. The technique is based on the administration of non-toxic photosensitizing agent patient subsequent localized exposure light source specific wavelength, resulting in cytotoxic response oxidative damage. present study intended evaluate vitro type induced death and genotoxic mutagenic effects PDT alone associated cisplatin.We used cell lines SiHa...
Eugenia jambolana has been used as an antioxidant, anti-inflammatory and antidiabetic. This study performed a chemical chemopreventive screening of extracts fractions from leaves fruits jambolana. The purification the crude extract afforded two known flavonoids, tricetin-4′-O-α-l-rhamnopyranoside (1), myricitrin (2), whereas one anthocyanin, malvidin-3-O-gentibioside (3). Additionally, seven anthocyanins were tentatively identified. antigenotoxicity results showed that post-treatment with...
This study evaluated the potential of Baccharis trimera essential oil (EO) and its components in cancer therapy through application cytotoxicity cell death assays. Using gas chromatography analysis, major aerial parts were identified as (E)-caryophyllene (18.9%), bicyclogermacrene (15.6%), germacrene D (10.5%). (5.8 μg/mL) α-humulene (7.8 presented strong cytotoxic activity, while (11.5 caryophyllene oxide (> 100.0 showed moderate low activities, respectively, against MCF-7 lines. Against...
Abstract Background Childhood obesity is a growing public health concern worldwide, with prevalence rates increasing in recent decades. This epidemic not only predisposes children to immediate risks such as cardiovascular disease and musculoskeletal problems but also significantly increases their risk of obesity-related comorbidities adulthood. Recognizing the multifactorial nature pediatric obesity, interventions targeting lifestyle modifications are crucial its control. Among these...
The volatile oils extracted from the roots of Polygala extraaxillaris were analyzed to assess whether they increase oxidative stress in Brachiaria decumbens var. Piatã, as well their effect on cellular division and cytotoxicity laboratory. Six concentrations used (0%, 0.35%, 0.65%, 1.25%, 5.0%) with four repetitions 25 seeds. substance 1-(2-hydroxyphenyl) - ethanone was identified major constituent oils. results showed that highest resulted an B. decumbens, alteration germination growth, a...
OF Buddleja stachyoides Cham.& Schltdl.(Scrophulariaceae).Phenylpropanoid glycoside verbascoside was isolated and identified from the ethyl acetate fraction of aerial parts Schltdl.by 1H-NMR.A method using high-performance liquid chromatography has been developed validated for determination in alcoholic crude extract B. stachyoides.Analysis performed on a Phenomenex® Gemini-NX C18 analytical column (250 mm × 4.6 mm; 5 µm) mobile phase (pump A -aqueous solution containing H 2 SO 4 (0.01 M), 3...
Devido à poluição gerada pela utilização dos combustíveis fósseis e também a sua escassez no futuro próximo, formas de produção mais eficientes biocombustíveis vêm sendo estudadas. Uma promissora se dá por oxidação em células combustível (FC), gerando energia elétrica forma limpa. Assim, neste trabalho foram preparados eletrocatalisadores Pt/Ti com adição CeO2, o objetivo aplicá-los na reação eletrooxidação etanol. Foram catalisadores três diferentes composições contendo Pt CeO2...
O comportamento eletroquímico de catalisadores formados por Pt-CeO2 foi investigado em meio básico pela técnica voltametria cíclica. Os materiais foram preparados decomposição térmica precursores poliméricos nas composições 50% Pt e CeO2 (Ce50Pt50/Ti); 30% 70% (Ce70Pt30/Ti); 100% (CeO2/Ti). resultados mostraram que o eletrodo Ce50Pt50/Ti apresentou semelhante ao da platina policristalina básico, enquanto mesmo não observado para a composição Ce70Pt30/Ti. Além disso, maior área...
Buddleja stachyoides Cham. & Schltdl. é uma espécie nativa do Brasil, não endêmica, comum nas regiões Nordeste (Bahia, Alagoas), Centro-Oeste (Distrito Federal), Sudeste e Sul. É conhecida popularmente como calção de velho ou verbasco, pertence a família Scrophulariaceae. Apesar ser usada na medicina tradicional, os estudos que caracterizam esta quanto às suas atividades biológicas são escassos existem relatos sobre seus parâmetros físico-químicos. Uma vez estes dados necessários para...
A espécie vegetal Rhamnus sphaerosperma var. pubescens, que é nativa no Brasil, apresenta um grande potencial farmacológico por ser enquadrada gênero Rhamnus, e possui poucos estudos relatam suas propriedades biológicas, ainda não foram descritos os parâmetros físico-químicos para o controle de qualidade da matéria-prima desta espécie. Sendo assim, neste trabalho, físico-químicos, como teor umidade, cinzas totais insolúveis em ácido determinados pela primeira vez esta Também foi realizada a...