A5082589229- Chemical synthesis and alkaloids
- Fungal Biology and Applications
- Mitochondrial Function and Pathology
- Silymarin and Mushroom Poisoning
- Phytochemistry and Bioactivity Studies
- Archaeological and Geological Studies
- Alzheimer's disease research and treatments
- Law, Ethics, and AI Impact
- Archaeological and Historical Studies
- Karst Systems and Hydrogeology
- Cholinesterase and Neurodegenerative Diseases
- Neuroscience and Neuropharmacology Research
Center for Biomedical Research of La Rioja
2020
Universidad de Navarra
2011
The mitochondrial voltage-dependent anion channel 1 (VDAC1) is involved in the release of apoptotic proteins with possible relevance Alzheimer's disease (AD) neuropathology. Through proteomic analysis followed by Western blotting and immunohistochemical techniques, we have found that VDAC1 overexpressed hippocampus from amyloidogenic AD transgenic mice models. was also postmortem brain tissue patients at an advanced stage disease. Interestingly, amyloid-β (Aβ) soluble oligomers were able to...
Mushrooms have been used for millennia as cancer remedies. Our goal was to screen several mushroom species from the rainforests of Costa Rica, looking new antitumor molecules. Mushroom extracts were screened using two human cell lines: A549 (lung adenocarcinoma) and NL20 (immortalized normal lung epithelium). Extracts able kill tumor cells while preserving non-tumor considered “anticancer”. The with better properties Macrocybe titans. Positive fractionated further tested biological activity...
En este artículo se presentan los datos de temperatura y humedad obtenidos entre 2018 2020 a diferentes profundidades (entrada, -350 m, -450 m -680 m) en la cavidad Torca Marino (Parque Nacional Picos Europa, León) que, con un desnivel -943 es una las mayor desarrollo vertical del mundo. Los muestran interior 4,6 ºC 4,7 5,1 4,8 ambiente siempre saturado condiciones homotérmicas, aunque pequeñas fluctuaciones hasta 0,4 el sector Gran Mulata, gradiente muy bajo (0,06 cada 100 distintas...
Abstract Mushrooms have been used for millennia as cancer remedies. Our goal was to screen several species from the rain forest of Costa Rica looking new antitumor molecules. Mushroom extracts were screened using two human cell lines: A549 (lung adenocarcinoma) and NL20 (immortalized normal lung epithelium). Extracts able kill tumor cells while preserving nontumor considered “anticancer”. The mushroom with better properties Macrocybe titans . Positive fractionated further tested biological...
Abstract Mushrooms have been used for millennia in Eastern traditional medicine as cancer remedies and recent scientific studies corroborated the presence of anticancer molecules mushroom extracts. Our goal this study was to screen a number scarcely known species collected rain forest Costa Rica looking new antitumor molecules. Mushroom pieces were subjected diverse extraction procedures involving water or ethanol at different temperatures. Extracts screened using two human cell lines: A549...