A5015593138- Enzyme Production and Characterization
- Biofuel production and bioconversion
- Diet, Metabolism, and Disease
- Fungal Biology and Applications
- Advanced Glycation End Products research
- Natural Antidiabetic Agents Studies
- Enzyme Catalysis and Immobilization
- Microbial Metabolites in Food Biotechnology
- Gut microbiota and health
- Alzheimer's disease research and treatments
- Vanadium and Halogenation Chemistry
- Pharmacology and Obesity Treatment
- Fungal and yeast genetics research
- Algal biology and biofuel production
- Proteins in Food Systems
- Vitamin C and Antioxidants Research
- Phytochemicals and Medicinal Plants
- Diet and metabolism studies
- Heme Oxygenase-1 and Carbon Monoxide
- Exercise and Physiological Responses
- Antioxidant Activity and Oxidative Stress
- Medicinal Plants and Bioactive Compounds
- Genetics, Aging, and Longevity in Model Organisms
- Clostridium difficile and Clostridium perfringens research
- Birth, Development, and Health
Maulana Abul Kalam Azad Institute of Asian Studies
2011-2025
Maulana Azad Medical College
2012-2022
ICAR-National Research Centre on Pig
2018
University of Calcutta
2016
University of Manchester
2012
Wellcome Centre for Cell-Matrix Research
2012
Indian Institute of Chemical Biology
2008-2011
Objective Obesity and overweight are challenging health problems of the millennium that lead to diabetes, hypertension, dyslipidemia, nonalcoholic fatty liver disease (NAFLD), atherosclerosis. Green coffee bean exhibited significant promise in healthy weight management, potentiating glucose-insulin sensitization supporting health. The safety efficacy a novel, patented water-soluble green extract (GCB70® enriched 70% total chlorogenic acid <1% caffeine) was investigated 105 participants for...
Morin (3,5,7,2′,4′-pentahydroxyflavone) is a flavonoid compound exhibited range of biological functions, including anti-inflammatory, antioxidant, antiviral, and anti-allergic activities. It has the ability to disaggregate amyloid fibrils, making it potential inhibitor diseases caused by protein fibrillation. This study focuses on interaction between Curli which are produced some Enterobacteriaceae, Salmonella sp. E. coli, as major component their biofilms. The fibrils can lead...
Abstract BACKGROUND Bioremediation using enzymes has become an attractive approach for removing hazardous chemicals from the environment. The present study investigated production, optimization and applications of extracellular alkaline protease (AkP) edible mushroom Termitomyces clypeatus focusing on bioremediation. RESULTS For optimized enzyme variables significantly influencing activity were screened through 11 factorial Plackett–Burman design. optimum values selected their mutual...
Non-enzymatic glycation of proteins is believed to be the root cause high dietary sugar associated pathophysiological maladies. We investigated structural changes in protein during progression using ribosylated Bovine Serum Albumin (BSA). Non enzymatic attachment about 45 ribose molecules BSA resulted gradual reduction hydrophobicity and aggregation as indicated by red-shifted tryptophan fluorescence, reduced ANS binding lower anisotropy FITC-conjugated protein. Parallely, there was a...
Background Trigonella foenum-graecum (Fenugreek) is an extensively researched phytotherapeutic for the management of Type 2 diabetes without any associated side effects. The major anti-diabetic bioactive constituents present in plant are furostanolic saponins, which more abundantly available seed plant. However, bioavailability these components depends on method extraction and hence formulation constitutes a critical step its success.Objective study reports efficacy novel, patented fenugreek...
Background: Fenugreek plant (Trigonella foenum-graecum) constitutes a traditionally acclaimed herbal remedy for many human ailments including diabetes, obesity, neurodegenerative diseases, and reproductive disorders. It is also used as an effective anti-oxidative, anti-inflammatory, antibacterial, anti-fungal agent. The seed of the especially enriched in several bioactive molecules polyphenols, saponins, alkaloids, flavonoids has demonstrated potential to act antidiabetic phytotherapeutic. A...
Background:Withania somnifera (L.) Dunal, popularly known as Ashwagandha, is an ethnomedicinal plant with multiple pharmacotherapeutic applications. The diverse medicinal properties of the are largely due to presence withanolides, a group C28 ergostane based steroidal lactones, several sites unsaturation and oxygenation. Withaferin A, major anolide present in Ashwagandha accounts for its emerging new roles treat cancer, arthritis, inflammatory responses, immunomodulatory properties, neuronal...
Abstract: Non-enzymatic protein glycation occurs spontaneously via the formation of sugarprotein Schiff adducts. The end products this pathway are terminally misfolded proteins popularly known as Advanced Glycation End (AGE) Products. Glycated account for a diverse spectrum physiological maladies including arteriosclerosis, renal failure, diabetic complications, obesity, and neurological disorders. AGEs not only jeopardise functionality modified but also induce Covalent cross-links. has...