A5003810132- Coronary Interventions and Diagnostics
- Peripheral Artery Disease Management
- Vascular Procedures and Complications
- Aortic aneurysm repair treatments
- Cerebrovascular and Carotid Artery Diseases
- Central Venous Catheters and Hemodialysis
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Electrospun Nanofibers in Biomedical Applications
- Renal and Vascular Pathologies
- Cardiac and Coronary Surgery Techniques
- Intracranial Aneurysms: Treatment and Complications
- Vascular anomalies and interventions
- Cardiac Valve Diseases and Treatments
- Angiogenesis and VEGF in Cancer
- Antiplatelet Therapy and Cardiovascular Diseases
- Aortic Disease and Treatment Approaches
- Hemodynamic Monitoring and Therapy
- Cardiovascular Health and Disease Prevention
- Diagnosis and Treatment of Venous Diseases
- Infectious Aortic and Vascular Conditions
- Blood Coagulation and Thrombosis Mechanisms
- Acute Ischemic Stroke Management
- Diabetic Foot Ulcer Assessment and Management
Advocate Lutheran General Hospital
2015-2025
Western Michigan University
2023
Pulmonary Vascular Research Institute
2022
University of Illinois Chicago
2000-2022
University of Illinois Urbana-Champaign
2018
University of Chicago
1998-2017
Abbott Vascular (United States)
2007-2016
Abbott (United States)
2004-2016
Cedars-Sinai Medical Center
2015
Abbott Fund
2005-2013
Background— Drug-coated balloons are increasingly used for peripheral vascular disease, and, yet, mechanisms of tissue uptake and retention remain poorly characterized. Most systems to date have paclitaxel, touting its propensity associate with various excipients that can optimize transfer retention. We examined zotarolimus pharmacokinetics. Methods Results— Animal studies, bench-top experiments, computational modeling were integrated quantify arterial distribution after zotarolimus-coated...
Although recognition of chronic mesenteric ischemia has increased in recent years, this disorder continued to present diagnostic and therapeutic challenges.To examine the modern results surgical revascularization for ischemia.Retrospective review.University medical center.The management 24 consecutive patients (mean +/- SEM age, 58 3 years; 5 men, 19 women) who were undergoing treatment between 1986 1996 was reviewed.Surgical revascularization.Postoperative course, long-term graft patency...
Background— Drug-coated balloons are rapidly emerging as a therapeutic alternative for the interventional treatment of peripheral vascular disease. The purpose this study was to test hypothesis that an angioplasty balloon coated with mTOR inhibitor zotarolimus (ZCB) would inhibit neointimal hyperplasia in novel injury-based superficial femoral artery model familial hypercholesterolemic swine. Methods and Results— A total 44 swine were included (12 designated tissue pharmacokinetics 32 safety...
Intimal hyperplasia is an important factor in the pathophysiology of vein graft failure. Local renin-angiotensin systems recently have been shown to modulate development intimal arteries after injury. The effect chronic angiotensin-converting enzyme (ACE) inhibition on experimental grafts was examined this study. Ten New Zealand White rabbits received 10 mg/kg captopril daily their drinking water. One week later right carotid artery divided and bypassed with reversed external jugular these...
Coronary and peripheral angiography is associated with a low but significant risk of access site complications. While percutaneous devices have been shown to permit more rapid puncture closure, previous reports suggested the incidence severity complications these are greater than manual compression. This study compares without closure in current era. The authors conducted retrospective review patients after coronary or between 1998 2000. Forty-five requiring vascular surgical consultation...
The purpose of this prospective clinical investigation was to quantify the degree and range compressive bending deformations sustained by self-expanding nitinol stents when implanted into femoropopliteal arteries patients with symptomatic peripheral vascular disease (PVD).Twenty-three (Absolute; Abbott Vascular, Santa Clara, CA, USA) diameters ranging from 5-10 mm lengths 40-100 were in 19 lesions 18 extremities 17 patients. Two days following implantation, vivo stent compression assessed...
SCHWARTZ, LEWIS B. M.D.Editor(s): Longmire, William P. Jr. M.D.; Lyerly, H. Kim M.D. Author Information