A5044649382- Metal-Catalyzed Oxygenation Mechanisms
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Genetic diversity and population structure
- Animal Diversity and Health Studies
- Genetic and phenotypic traits in livestock
- Porphyrin Metabolism and Disorders
- Animal Genetics and Reproduction
- Chromosomal and Genetic Variations
- Ferroptosis and cancer prognosis
- Metal complexes synthesis and properties
- Pediatric Hepatobiliary Diseases and Treatments
- Peptidase Inhibition and Analysis
- Gallbladder and Bile Duct Disorders
- Circular RNAs in diseases
- Enzyme Structure and Function
- Antimicrobial Resistance in Staphylococcus
- MicroRNA in disease regulation
- Genetic Mapping and Diversity in Plants and Animals
Karolinska Institutet
2025
University of Padua
2022
Stockholm University
2021-2022
Institut des Régions Arides
2015
Abstract Ribonucleotide reductase (RNR) is an essential enzyme that catalyzes the synthesis of DNA building blocks in virtually all living cells. NrdR, RNR-specific repressor, controls transcription RNR genes and, often, its own, most bacteria and some archaea. NrdR senses concentration nucleotides through ATP-cone, evolutionarily mobile domain also regulates enzymatic activity many RNRs, while a Zn-ribbon mediates binding to boxes upstream overlapping start site genes. Here, we combine...
One of the main tasks PROCAMED project is to promote research on genetics dromedary camel. In this regard, and evaluate genetic diversity among Tunisian camel, a total 62 blood samples were collected from unrelated animals in three different regions (Tataouine, Medenine Kebili) belonging sub-populations (Ourdhaoui Médenine, Ourdhaoui Tataouine Merzougui) defined basis morphologic geographic criterions. From seven microsatellite markers used only four successfully amplified resulting 26...
This study analyzed the genetic variability, inbreeding and population structure of Tunisian-North African dairy sheep breed, Sicilo-Sarde (SS), created by crossing Sarda Comisana breeds. The level variability in SS, considered as an endangered breed after a dramatic decrease, was assessed using 17 microsatellite markers analyzing two populations sampled from their respective cradles: SS Beja (SS
Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleotides to corresponding deoxyribonucleotides, building blocks DNA. RNRs are specific for either ribonucleoside diphosphates or triphosphates as substrates. As far is known, oxygen-dependent class I (NrdAB) all reduce diphosphates, and oxygen-sensitive III (NrdD) triphosphate reducers, whereas adenosylcobalamin-dependent II (NrdJ) contains both diphosphate reducers. However, it unknown how this specificity conveyed by active...