S. munja roots have been used in ethno medicines for the treatment of different ailments. Despite its beneficial uses no studies on toxicity potential reported.The study was designed to evaluate acute toxic aqueous ethanolic extract according OECD TG No. 425.Female mice were divided into two groups (n = 5). One group served as control while other treated that received 2000 mg/kg b.w. orally. Then both observed 14 days. blood samples collected by cardiac puncture, under chloroform general...

Alzheimer's disease (AD) is a neurodegenerative characterized by cascade of changes in cognitive, behavioral, and social activities. Several areas the brain are involved regulation memory. Of most importance amygdala hippocampus. Antioxidant therapy used for palliative treatment different degenerative diseases like diabetes, cirrhosis, Parkinson's, etc. The objective this study was to assess effectiveness exogenous antioxidants, particular, β carotene (1.02 2.05 mg/kg) against...

Medicinal plants represent an important source of alternative medicine for the management various diseases. The present study was undertaken to assess potential

Research Article| February 01 1935 Observations on the chemical method for estimation of vitamin C Bashir Ahmad 1The Department Biochemistry and Nutrition, All-India Institute Hygiene Public Health, Calcutta Search other works by this author on: This Site PubMed Google Scholar Biochem J (1935) 29 (2): 275–281. https://doi.org/10.1042/bj0290275 Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Facebook Twitter LinkedIn MailTo Cite Get Permissions...

Schizophrenia, a global mental health disorder affecting approximately 1 % of the population, is characterized by neurotransmitter dysregulation, particularly dopamine, serotonin, and glutamate. Current antipsychotic therapies, despite their efficacy, are accompanied adverse effects, which has motivated researchers to investigate more secure substitutes. This study examines potential effects esculetin, natural coumarin derivative recognized for its wide-ranging pharmacological activities...

is being used as a folk remedy for treating arthritis by conventional healers in Thailand. The current research was undertaken to explore the antiarthritic potential of

Drugs obtained from medicinal plants have always played a pivotal role in the field of medicine and to identify novel compounds. Safety profiling plant extracts is utmost importance during discovery new biologically active compounds determination their efficacy. It imperative conduct toxicity studies before exploring pharmacological properties perspectives any plant. The present work aims provide detailed insight into phytochemical toxicological methanolic extract Zephyranthes citrina (MEZ)....

Aggression is a major hallmark worldwide attributing negative traits in personality. Wide variety of antioxidants used for the treatment many ailments. The present study was conducted to evaluate role such as ascorbic acid (15.42 and 30.84 mg/kg), beta carotene (1.02 2.05 vitamin E (2.5 5.0 N-acetyl cysteine (102.85 205.70 mg/kg) aggression. Two aggression models (isolation induced model L-DOPA model) were study. Male albino mice (n = 330) which further subdivided into 11 groups (Group...

Alzheimer's disease (AD) is the neurodegenerative disorder characterized by impairment of higher intellectual dysfunctions associated with changes in cognitive, behavioral, and social activities. Aim study: The current study was designed to evaluate potential aldosterone antagonist treatment AD. Methodology: conducted on albino mice either sex (n = 60). Mice were subcategorized into six groups, each group having 10 mice. Group I—normal control (CMC 1 mL/kg), II—diseased [streptozotocin...

This study explores the social interaction between leaders and employees at Biak Marine Fisheries Resources Monitoring Station Office. topic was chosen because of importance in forming a productive work culture an inclusive environment, especially context leadership changes employee cultural diversity. The purpose this is to understand how associative affects motivation team dynamics office. used qualitative method with descriptive approach. Data were collected through direct observation,...

Convolvulus arvensis is traditionally used as laxative. Its decoction in cough, flu, jaundice and skin diseases. It also to treat the painful joints, inflammation swelling. The current study was conducted determine its hepatoprotective activity. results showed that extract of C. (200 mg/kg 500 mg/kg) produced significant (p<0.05) decrease paracetamol induced increased levels liver enzymes total bilirubin. Histopathological investigation detection active constituent, qurecetin by HPLC...

Mortality rate is increasing due to cardiovascular problems throughout the world. These cardiac are directly associated with dyslipidemia.

Tribulus terrestris (T.T.) is a rich source of flavonoids and saponins, which have been reported to neuroprotective antioxidant potential. The current study was planned investigate the anti-Parkinson's activity T. methanol extract (TTME). It hypothesized that TTME possessed potential can ameliorate Parkinson's disease (PD) via modulation α-synuclein, acetylcholinesterase (AChE), TNF-α, IL-1β. To test this hypothesis, in silico vivo studies were performed. PD model rats prepared by giving...

A facile, green synthesis of selenium doped zinc oxide nano-antibiotic (Se-ZnO-NAB) using the<italic>Curcuma longa</italic>extract is reported to combat the increased emergence methicillin-resistant<italic>Staphylococcus aureus</italic>(MRSA).

Research Article| January 01 1936 Observations on the excretion of vitamin C in human urine Bashir Ahmad 1The Department Biochemistry and Nutrition, All India Institute Hygiene Public Health, Calcutta Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1936) 30 (1): 11–15. https://doi.org/10.1042/bj0300011 Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Facebook Twitter LinkedIn Email Cite Get Permissions Citation...

The oxadiazole ring has long been used for the treatment of several diseases. This study aimed to analyze antihyperglycemic and antioxidant roles 1,3,4-oxadiazole derivative with its toxicity. Diabetes was induced through intraperitoneal administration alloxan monohydrate at 150 mg/kg in rats. Glimepiride acarbose were as standards. Rats divided into groups normal control, disease standard, diabetic rats (treated 5, 10, 15 derivative). After 14 days oral derivatives (5, mg/kg) group, blood...

To evaluate in vivo antioxidant activity of latex and leaves methanol extract Euphorbia helioscopia using mice as experimental animals.The plant was collected, identified, dried under shade, ground to fine powder extraction done. Latex collected bottles by cutting the stem. Oxidative stress induced with acute toxic dose paracetamol administered intrperitoneally. (600 1 200 mg/kg) orally, once a day, were given for two weeks. Then oxidative biomarkers measured tissue homogenates serum.Leaves...

Background and Objectives: Alzheimer's disease (AD) is a neurodegenerative disorder that deteriorates daily life due to loss of memory cognitive impairment. It believed oxidative stress cholinergic deficit are the leading causes AD. Disease-modifying therapies for treatment AD challenging task this century. The search natural synthetic agents has attracted attention researchers. objective study was scientific approach most suitable remedy by exploiting potential Albizia lebbeck (L.) seeds....