A5101614204- Amyotrophic Lateral Sclerosis Research
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Inflammatory Bowel Disease
- Genetic Neurodegenerative Diseases
- Neurogenetic and Muscular Disorders Research
- Muscle Physiology and Disorders
- Microscopic Colitis
- Mitochondrial Function and Pathology
- Gastric Cancer Management and Outcomes
- Alzheimer's disease research and treatments
- Neuroscience and Neuropharmacology Research
- Colorectal Cancer Screening and Detection
- Genetics and Neurodevelopmental Disorders
- Diet and metabolism studies
- RNA and protein synthesis mechanisms
- Prion Diseases and Protein Misfolding
- Cardiac, Anesthesia and Surgical Outcomes
- Epilepsy research and treatment
- Microtubule and mitosis dynamics
- Neurogenesis and neuroplasticity mechanisms
- Genomics and Chromatin Dynamics
- RNA modifications and cancer
- Sleep and Wakefulness Research
- Nuclear Receptors and Signaling
Metabolon (United States)
2022-2024
University Hospitals of Leicester NHS Trust
2011-2024
University of Manchester
1987-2023
Salford Royal NHS Foundation Trust
2014-2023
University of Indianapolis
2022-2023
Portsmouth Hospitals NHS Trust
2023
The Christie Hospital
2014-2022
Cornell University
1986-2022
Queen Alexandra Hospital
2018-2022
Hywel Dda University Health Board
2016-2022
Case Reports1 July 1953FATAL ADRENAL CORTICAL INSUFFICIENCY PRECIPITATED BY SURGERY DURING PROLONGED CONTINUOUS CORTISONE TREATMENTLEON LEWIS, M.D., F.A.C.P., ROBERT F. ROBINSON, JAMES YEE, LUCY A. HACKER, GEORGE EISEN, M.D.LEON M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-1-116 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONWhen hyperadrenocorticism is...
Significant progress has been made in understanding the pre-symptomatic phase of amyotrophic lateral sclerosis. While much is still unknown, advances other neurodegenerative diseases offer valuable insights. Indeed, it increasingly clear that well-recognized clinical syndromes Alzheimer's disease, Parkinson's Huntington's spinal muscular atrophy and frontotemporal dementia are also each preceded by a or prodromal period varying duration, during which underlying disease process unfolds, with...
Changes in the fibrinolytic system may lead to coagulation disorders acute trauma patients. This study examined fibrin degradation by measuring D-dimer crosslinked products (indicates hypercoagulability), plasminogen activators (fibrinolysis), and antithrombin III 42 adult patients correlated these data with injury severity, types of injury, complications, clinical tests coagulation. Hypercoagulability suppression fibrinolysis were seen most not severity injury. These changes appeared severe...
ABSTRACT BACKGROUND AND PURPOSE Susceptibility-Weighted Imaging (SWI) is a relatively new magnetic resonance imaging (MRI) sequence relying on susceptibility differences between adjacent tissues to produce an image. It extremely sensitive for detection of blood products (hemosiderin, ferritin), deoxygenated blood, calcium, iron, and small vein depiction. Little information available in the literature describe common findings seen using this sequence. This article comprehensive review...
Objective To compare the complication rate associated with synchronous prosthesis insertion at time of radical orchidectomy alone. Patient and Methods All men undergoing for testis cancer in N orth W est R egion E ngland between A pril 1999 to J uly 2005 ovember 2007 2009 were included. Data on postoperative complications, length stay ( LOS ), re‐admission return theatre collected. Results In all, 904 [median (range) age 35 (14–88) years], underwent a during study period 413 (46.7%) offered...
Similarities between Johne's disease in ruminants and Crohn's humans have led to speculation that Mycobacterium avium paratuberculosis (MAP) might be a causative agent disease. However, evidence remains inconsistent. In this case-control study (1999–2004), the authors assessed possible role of drinking water dairy products potentially contaminated with MAP etiology A total 218 patients recruited from nine hospitals England 812 controls community completed short questionnaire for evaluation...
RNA interference (RNAi) is used in the lab to silence virtually any gene. Previously, antisense and ribozymes were successful lab, but have been disappointing clinic. Will RNAi succeed where these two not?
BACKGROUND: The use of phthalocyanines in conjunction with red light has been shown to inactivate model lipid‐enveloped viruses cell concentrates. ability this treatment multiple forms human immunodeficiency virus (HIV) was evaluated study. STUDY DESIGN AND METHODS: used were aluminum phthalocyanine tetrasulfonate (AIPcS4) and the silicon HOSiPcOSi(CH3)2(CH2)3 N(CH3)2 (Pc 4), HOSiPcOSi(CH3)2 (CH2)3N+(CH3)3I‐(Pc 5). HIV studied a cell‐free form, an actively replicating latently infected...
Summary Background Systemic corticosteroids are effective in ulcerative colitis but commonly cause side effects. Aim To compare the safety and efficacy of a sparingly absorbed formulation prednisolone metasulfobenzoate (Predocol) with conventional tapering course oral prednisolone. Method In double‐blind randomized study, 59 active patients received Predocol 40 mg/day for 6 months, 61 60 months 2 weeks, tapered to week 8, followed by placebo until months. Results Steroid‐related effects...