A5025775493- Heart Rate Variability and Autonomic Control
- Apelin-related biomedical research
- Hormonal Regulation and Hypertension
- Kawasaki Disease and Coronary Complications
- Heart rate and cardiovascular health
- Cardiovascular Function and Risk Factors
- COVID-19 and healthcare impacts
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Acute Myocardial Infarction Research
- Blood Coagulation and Thrombosis Mechanisms
- Inflammation biomarkers and pathways
- Pulmonary Hypertension Research and Treatments
- Sodium Intake and Health
- Cardiovascular Health and Disease Prevention
- Electroconvulsive Therapy Studies
- Vitamin C and Antioxidants Research
- Thermoregulation and physiological responses
- Coronary Artery Anomalies
- Healthcare cost, quality, practices
- COVID-19 Clinical Research Studies
- Pancreatitis Pathology and Treatment
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Cardiovascular Effects of Exercise
- Cardiac Health and Mental Health
Istanbul Metropolitan Municipality
2024-2025
İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
2025
Bezmiâlem Vakıf Üniversitesi
2024
Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi
2015-2020
Sağlık Bilimleri Üniversitesi
2019-2020
Başkent University
2016
Delayed admission of myocardial infarction (MI) patients is an important prognostic factor. In the present nationwide registry (TURKMI-2), we evaluated treatment delays and outcomes with acute MI during Covid-19 pandemic compaired a recentpre-pandemic (TURKMI-1).The pre-pandemic studies were conducted prospectively as 15-day snapshot registries in same 48 centers. The inclusion criteria for both aged ≥18 years final diagnosis (AMI) positive troponin levels. only difference between 2 was that...
Coronary artery ectasia (CAE) is a vascular anomaly characterized by abnormal coronary dilation, often associated with endothelial dysfunction and inflammation. While CAE shares features disease (CAD), its independent pathophysiology remains unclear, particularly in cases without concurrent CAD. To evaluate oxidative antioxidant biomarker levels patients isolated to understand their role pathogenesis. Our study was conducted involving 48 32 controls normal angiograms. Oxidative stress...
Background: Delay on admission of myocardial infarction (MI) is an important prognostic factor. In this nationwide registry, we compared treatment delays and outcomes patients with acute MI in Covid-19 pandemic period a recent pre-pandemic registry conducted at the same centres. Methods: A (TURKMI-1) enrolled consecutive November 1-15, 2018 Turkey, assessed time delay each step from symptom-onset to outcomes. Fifty centres were selected using probability sampling. present study (TURKMI-2),...
There are limited studies on the effects of asthma cardiac function. Right ventricular dysfunction and pulmonary hypertension cardiovascular complications that may be seen in advanced stages disease. Pulmonary artery stiffness (PAS), is a promising, relatively new echocardiographic index has been reported to increase right failure, providing information about vascular bed.In this study, we aimed evaluate PAS, marker elasticity, adult-onset asthma.Ninety-nine nonsmokers who had diagnosis...
We examined the change in apelin concentration and its relationship with left ventricular diastolic function patients treated for hypertension.
There is limited number of studies on the effect asthma disease cardiac functions. The aim this study was to investigate if there any association between adult onset and dysfunction.Total 83 nonsmoking patients aged 18 65, control subjects with comparable age sex distribution were included in study.None had chronic cardiovascular or systemic diseases.Two-dimensional, M-mode tissue Doppler examinations performed. STE analysis obtained using QLAB software. Complete blood count high-sensitive...
To evaluate the epicardial fat tissue thickness (EFTT) as a diagnostic criterion for geriatric patients with metabolic syndrome (MetS).Sixty over 65 years of age were recruited study. Patients divided into two groups: Group 1 (n = 30) consisted MetS; 2 without MetS. Echocardiography was used to measure EFTT in all patients, and blood samples analyzed biochemical parameters.Compared 2, levels statistically higher (P < 0.05). In binary logistic regression analysis, served independent factor (B...
Recent studies have focused on the probable role of oxidative stress in cardiovascular diseases. We aimed to assess oxidant/antioxidant biomarkers coronary slow flow (CSF).
Endothelial dysfunction may play an important role in the evolution of coronary artery ectasia (CAE). Endocan and thrombomodulin (TM) are two biomarkers released from endothelium that associated with dysfunction. We aimed to evaluate levels these markers patients isolated CAE.Thirty-two CAE thirty-five sex- age-matched control normal angiograms were enrolled. Serum endocan TM concentrations measured enzyme-linked immunosorbent assay kit.The basal characteristics groups similar. Both (1.19 ±...
Aims: In this study, we aimed to compare the carotid intima media thickness in patients with treatment-regulated hypertension without coronary artery disease normal population. Methods: A total of 62 arteries detected after elective angiography; 32 and 30 regulated by drug therapy were enrolled study. Results: study conducted our clinic, no statistically significant difference was found between group whose treatment, control group. Conclusion: The fact that thicknesses not be different...
Salt is important in the pathogenesis of hypertension (HT). Salt-sensitive (SSH) accounts for about half all HT cases. In SSH, sodium/potassium adenosine triphosphatase (Na+/K+-ATPase) activity impaired. Impaired Na+/K+-ATPase lens epithelium results cortical opacities peripheral equator lens. We investigated sensitivity detecting SSH.The study included 191 SSH and 159 non-SSH, salt-resistant (SRH) patients (350 total), aged 40-80 years. One hundred twenty-four sex- age-matched without a...
The existence of the retinohypothalamic pathway suggests that light may influence autonomic outflow activity. objective this study was to examine correlation between estimated iris muscle sympathetic-parasympathetic area (IRIS) ratio and sympathetic?parasympathetic (Low Frequency (LF)/High (HF) ratio). population consisted 200 females males (mean age, 32.4 ± 7.1 y). IRIS determined from digital photographs in a computer setting. LF/HF records heart rate variability obtained using Holter...
Background: Growing evidence suggests that endothelial dysfunction plays a key role in the pathophysiology of Slow Coronary Flow (SCF). This study investigated association between biomarkers endocan and soluble Thrombomodulin (sTM) SCF. Methods: The population consisted 89 subjects (54 patients with SCF 35 controls). flow rate was assessed using Thrombolysis Myocardial Infarction (TIMI) Frame Count (TFC) method. serum sTM levels all were analysed. Results: Significantly higher (1.14 ± 0.22...
Subacute stent thrombosis after acute coronary syndrome and concurrent of multiple arteries are rare complications. Schizophrenia antipsychotic drugs cause hypercoagulability, rates cardiovascular mortality higher in schizophrenic patients compared with the normal population. We want to discuss a case recurrent subacute left anterior descending artery right myocardial infarction patient. Learning Objectives: medications should be considered risk factors for treated percutaneous implantation....
Introduction: Although resting heart rate (RHR) and oxidative stress are risk factors for cardiovascular morbidity mortality, the association between them has not been fully understood. The aim of present study was to investigate relationship RHR oxidative/antioxidative markers. Patients Methods: consisted 56 healthy volunteers (33 males; mean age: 44.1 ± 9.0 years). Subjects were divided into two groups according quartiles: lower quartiles as group 1 (n= 29) upper 2 27). We measured total...
Objectives: Resting heart rate (RHR) is a physiological parameter that has been reported to be associated with endothelial dysfunction.Endocan and thrombomodulin are mediators released from endothelium, which determined increase in blood damage.We aimed investigate the relationship between RHR these biomarkers. Materials Methods:Sixty-eight healthy volunteers (28 females; mean age: 44.2±6.3 years) were included study.Subjects divided into two groups according quartiles: lower quartiles as...
Heart, lens, and neuronal cells change significantly with age, they are older than from renewable tissues. Near vision deterioration during aging results a decrease in accommodation amplitude (AA). Cardiac is an independent risk factor for cardiovascular disease. We investigated the association between cardiac AA.The subjects (500 mean 50-year-old subjects, equal males females) were divided into two groups according to AA measured Raf ruler. Biomicroscopy was used capture images of lens...
Background: Obese and hypertensive (HT) patients should restrict salt intake. In excessive intake, ouabain-like compounds inhibit Na/K-ATPase (Na+ pump), which increases intracellular Na+ Ca2+. Ca2+ has a vasotonic effect on arteries an inotropic the heart may cause cortical opacities in lens. To our knowledge, there is still no practical method for intake follow-up. This study tested whether follow-up can be performed with help of opacity tracking. Methods: total, 400 HT (age 30-69 years)...