Yu Li

ORCID: 0000-0003-0125-9367
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About
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Research Areas
  • Nanopore and Nanochannel Transport Studies
  • Spectroscopy and Quantum Chemical Studies
  • Iron Metabolism and Disorders
  • Polymer Science and PVC
  • Metalloenzymes and iron-sulfur proteins
  • Remote Sensing in Agriculture
  • Electrostatics and Colloid Interactions
  • Polymer composites and self-healing
  • Photochemistry and Electron Transfer Studies
  • Smart Agriculture and AI
  • Spectroscopy and Chemometric Analyses
  • Food composition and properties
  • Polysaccharides Composition and Applications
  • Enzyme Structure and Function
  • Additive Manufacturing and 3D Printing Technologies
  • Reproductive System and Pregnancy
  • Electrochemical Analysis and Applications
  • Advances in Cucurbitaceae Research
  • Cellular transport and secretion
  • Potato Plant Research
  • Remote Sensing and Land Use
  • Plant Stress Responses and Tolerance
  • Proteins in Food Systems
  • Plant Pathogenic Bacteria Studies
  • Pelvic floor disorders treatments

Zhejiang University
2011-2024

First Affiliated Hospital Zhejiang University
2022-2023

State Key Laboratory of Chemical Engineering
2020-2022

East China University of Science and Technology
2020-2022

Wenzhou Medical University
2022

State Key Laboratory of Rice Biology
2021-2022

China National Rice Research Institute
2021-2022

Zhejiang Taizhou Hospital
2022

Auburn University
2022

Nanjing University of Science and Technology
2013

Abstract Motivation: Protein–ligand binding sites are the active on protein surface that perform functions. Thus, identification of those is often first step to study functions and structure-based drug design. There many computational algorithms tools developed in recent decades, such as LIGSITEcs/c, PASS, Q-SiteFinder, SURFNET, so on. In our previous work, MetaPocket, we have proved it possible combine results methods together improve prediction result. Results: Here, continue work by...

10.1093/bioinformatics/btr331 article EN Bioinformatics 2011-06-02

Pelvic organ prolapse is a worldwide health problem to elderly women. Understanding its pathogenesis and an ideal animal model are crucial developing promising treatments. The present study aimed investigate new clinical significance detailed mechanism of pelvic by comparing the structural, functional molecular dysfunctions in patient Loxl1 deficient mice. Our results showed that human vagina tissues from prolapsed site disarranged collagen elastic fibers compared with non-prolapse tissue. A...

10.18632/aging.203777 article EN cc-by Aging 2021-12-19

Stem cell-based tissue regeneration strategies are promising treatments for severe endometrial injuries. However, there few appropriate seed cells regenerating a full-thickness endometrium, which mainly consists of epithelia and stroma. Müllerian ducts in female embryonic development develop into Hence, we first generated human pluripotent stem (hPSC)-derived duct-like (MDLCs) using defined effective protocol. The MDLCs bi-potent, can gradually differentiate epithelial stromal cells,...

10.1038/s41536-022-00263-2 article EN cc-by npj Regenerative Medicine 2022-11-23

High lipids in rice endosperm can lower the digestibility of starch. However, as tend to oxidize and hydrolyze, whether high is easily deteriorated during storage unknown. In this study, artificially accelerated ageing was adopted a fast way investigate changes physiochemical properties mutants (i.e. ALK3 RS4) storage. Ageing treatment did not affect total content, but NSL γ-oryzanol aged (2.30%, 113.6 μg/g) RS4 (2.10%, 72.2 significantly decreased. Aged had pH cooking solution (6.92) Tp...

10.1016/j.lwt.2021.112730 article EN cc-by-nc-nd LWT 2021-10-29

Abstract Whereas the separation by surface affinity represents an advanced technique for of nanoparticles with distinct properties, how interaction particles nanochannel impacts performance is less understood. Herein, dynamical density functional theory employed to study two types similar‐sized different affinities within nanochannels. We show that a proper design channel inner‐surface, which attracts one type while repelling other, can promote permeability and selectivity particles....

10.1002/aic.17583 article EN AIChE Journal 2022-01-07

Although ultra-small nanoclusters (USNCs, < 2 nm) have immense application capabilities in biomedicine, the investigation on body-wide organ responses towards USNCs is scant. Here, applying a novel strategy of single-cell mass cytometry combined with Nano Genome Atlas multi-tissues, we systematically evaluate interactions between host and calcium phosphate (CaP) at organism level. Combining cytometry, magnetic luminex assay results, identify dynamic immune to CaP single cell resolution. The...

10.1016/j.bioactmat.2022.03.026 article EN cc-by-nc-nd Bioactive Materials 2022-03-25

Abstract Starch is an important multifunctional ingredient for food, cosmetics, fuels, and pharmaceuticals. Naturally, starch hydrophilicity, while its’ absorbability varies among botanical sources physical or chemical modifications. In this study, fractioned A‐ B‐type wheat granules show different physiochemical properties, have greater water oil absorption capacity. After removing surface proteins with sodium dodecyl sulfate (SDS), granule morphology crystalline structure are not...

10.1002/star.202200002 article EN Starch - Stärke 2022-03-20

Abstract To explore the desirable chain structure and condensed of polyethylene used for biaxial stretching, blends two polyethylenes (PE1 PE2) with different molecular weight branch distribution were investigated. Their including relaxation crystallization behavior was studied by rheology, dynamic mechanical analysis (DMA), non‐isothermal kinetics. And microstructure characterized preparative temperature rising elution fractionation (P‐TREF), successive self‐nucleation annealing (SSA). It...

10.1002/app.49652 article EN Journal of Applied Polymer Science 2020-07-20

Abstract OBJECTIVES Locally advanced non-small-cell lung cancer (LA-NSCLC) requires more preoperative regiments in the era of immunotherapy. Tislelizumab was approved for first-line treatment cancer, bringing hope therapy LA-NSCLC. The aim this study to investigate safety and efficacy tislelizumab plus chemotherapy METHODS medical records at First Affiliated Hospital Zhejiang University were examined retrospectively from September 2019 June 2022 descriptive single-arm cohort study. Patients...

10.1093/icvts/ivad157 article EN cc-by Interdisciplinary CardioVascular and Thoracic Surgery 2023-09-19

Remote sensing information acquisition technology based on UAV has been widely used in the agricultural field. remote platform to obtain crop characteristics of high timeliness, resolution, low cost, rapidity and accuracy, is one important means obtaining farmland precision agriculture. Using multispectral images, taking wheat, barley Chinese cabbage as research objects, selecting different vegetation indices for image threshold segmentation, combining results machine learning classification...

10.1109/agro-geoinformatics55649.2022.9859063 article EN 2022-07-11

<title>Abstract</title> <italic>Cucumis melo</italic> L., commonly known as melon, is a crucial horticultural crop. The selection and breeding of superior melon germplasm resources play pivotal role in enhancing its marketability. However, current methods for appearance phenotypic analysis rely primarily on expert judgment intricate manual measurements, which are not only inefficient but also costly. Therefore, to expedite the process we analyzed images 117 varieties from two annual years...

10.21203/rs.3.rs-4341481/v1 preprint EN cc-by Research Square (Research Square) 2024-05-09
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