Qian Zhou

ORCID: 0000-0003-0138-6761
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About
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Research Areas
  • Blood Coagulation and Thrombosis Mechanisms
  • Advanced Glycation End Products research
  • Hemophilia Treatment and Research
  • Phytochemicals and Antioxidant Activities
  • Natural Antidiabetic Agents Studies
  • Liver Disease Diagnosis and Treatment
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Liver physiology and pathology
  • Food composition and properties
  • Biochemical effects in animals
  • Genomics, phytochemicals, and oxidative stress
  • Food Quality and Safety Studies
  • Birth, Development, and Health
  • Cancer-related gene regulation
  • Trace Elements in Health
  • Natural product bioactivities and synthesis
  • MicroRNA in disease regulation
  • Tea Polyphenols and Effects
  • Pregnancy and preeclampsia studies
  • Bone Metabolism and Diseases
  • Inflammasome and immune disorders
  • Alzheimer's disease research and treatments
  • Pancreatic function and diabetes
  • Radio Frequency Integrated Circuit Design
  • Adipose Tissue and Metabolism

Shenzhen University
2017-2025

Southeast University
2022-2025

Guangxi University
2023-2024

Jiangnan University
2024

State Key Laboratory of Food Science and Technology
2024

Shenzhen University Health Science Center
2018-2024

Shandong First Medical University
2023-2024

Nanjing University of Posts and Telecommunications
2024

Shandong Provincial Hospital
2023-2024

Wenzhou Medical University
2019-2024

It has been reported that disordered Cu metabolism is associated with several neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's (PD). However, the underlying mechanism still unclear. In this study, 4-week-old male mice were exposed to by free-drinking water for three months. Then, effects of on cognitive functions in tested Morris maze tests, potential mechanisms investigated ELISA, immunochemistry, TUNEL, Western blot tests. was found exacerbates learning memory...

10.3390/nu15040972 article EN Nutrients 2023-02-15

Objective: Oxytocin (OT) is synthesized within the paraventricular nucleus and supraoptic of hypothalamus. In addition to its role in uterine contraction, OT plays an important antinociceptive role; however, underlying molecular mechanisms remain elusive. We hypothesized that effect on neuropathic pain may occur via inhibition TRPV1 activation spinal cord. The present study explores pain. Methods: Partial sciatic nerve ligation (pSNL) was performed induce Animal behaviors were measured using...

10.3389/fnmol.2018.00248 article EN cc-by Frontiers in Molecular Neuroscience 2018-07-17

In vitro and in vivo models of Parkinson's disease were established to investigate the effects lncRNA XIST/miR-199a-3p/Sp1/LRRK2 axis. The binding between XIST miR-199a-3p as well Sp1 examined by luciferase reporter assay confirmed RNA immunoprecipitation analysis. Following animal behavioural assessment suspension swim tests, brain tissue injuries evaluated hematoxylin eosin, TdT-mediated dUTP-biotin nick end labelling, tyrosine hydroxylase stainings. results indicated that expression was...

10.18632/aging.202378 article EN cc-by Aging 2021-01-20

Abstract Pigeon pea ( Cajanus cajan L.) is one of the most important legume crops grown in subtropical and tropical regions with high nutritional quality. However, consumption pigeon very limited worldwide owing to its level anti‐nutrients, hard texture, unpleasant characteristic taste. The present review summarized profile health benefit special attention bioactive phytochemicals (e.g., cajanin, cajanol, cajaninstilbene acid). Furthermore, some aspects that can help promote application...

10.1002/fft2.381 article EN cc-by Food Frontiers 2024-03-11

Background and Purpose Liver fibrosis is commonly associated with obesity most obese patients develop hyperleptinaemia. The adipocytokine leptin has a unique role in the development of liver fibrosis. Activation hepatic stellate cells ( HSCs ) key step fibrogenesis sterol regulatory element‐binding protein‐1c SREBP ‐1c) can inhibit HSC activation. We have shown that strongly inhibits ‐1c expression rat . Hence, we aimed to clarify whether β‐catenin pathway, crucial negative regulator...

10.1111/bph.12114 article EN British Journal of Pharmacology 2013-01-24

It is well known that extensive osteoclast formation plays a key role in osteoporosis post‑menopausal women and the elderly. The suppression of osteoclastogenesis bone resorption may be an effective preventive strategy for osteoporosis. Zoledronic acid (ZOL) has been indicated to play essential regulating mineral density already used large clinical trials. However, effects ZOL on remain fully elucidated. Therefore, present study aimed determine osteoclastogenesis, explore corresponding...

10.3892/ijmm.2019.4207 article EN cc-by-nc-nd International Journal of Molecular Medicine 2019-05-23
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