Elena Manole

ORCID: 0000-0003-0164-859X
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Multiple Sclerosis Research Studies
  • Peripheral Neuropathies and Disorders
  • Long-Term Effects of COVID-19
  • Systemic Sclerosis and Related Diseases
  • Stroke Rehabilitation and Recovery
  • Intracranial Aneurysms: Treatment and Complications
  • S100 Proteins and Annexins
  • Innovations in Medical Education
  • Neurological Disorders and Treatments
  • Higher Education Learning Practices
  • Pharmacological Effects of Natural Compounds
  • Protease and Inhibitor Mechanisms
  • Advances in Oncology and Radiotherapy
  • Rheumatoid Arthritis Research and Therapies
  • Hereditary Neurological Disorders
  • Blood Coagulation and Thrombosis Mechanisms
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Dysphagia Assessment and Management
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Venous Thromboembolism Diagnosis and Management

Nicolae Testemițanu State University of Medicine and Pharmacy
2017-2023

ORCID
2021

Ischemic stroke (IS) remains one of the most frequent causes death and disability worldwide.Identifying possible prognosis factors for IS outcomes, including hemorrhagic transformation (HT), could improve patients' recovery.This study aimed to investigate potential role non-specific laboratory data at admission baseline MMP-2 MMP-9 serum levels in predicting HT risk, discharge, 3-month follow-up status patients.Data from 150 successive acute cerebral infarction patients were analyzed a...

10.25122/jml-2023-0148 article EN Journal of Medicine and Life 2023-06-01

Abstract Immunocompromised status keeps on being a challenge for neurologist, especially in the context of coronavirus disease – 19 (COVID-19) pandemic. We report clinical case human-immunodeficiency virus (HIV) - positive patient who developed an acute transverse myelitis. Magnetic Resonance Imaging (MRI) examination showed longitudinally extensive spinal cord abnormality, and laboratory tests confirmed SARS-CoV-2 infection. The responded to methylprednisolone pulse therapy therapeutic...

10.21203/rs.3.rs-50901/v1 preprint EN cc-by Research Square (Research Square) 2020-08-02

Overlapping central nervous system (CNS) and peripheral (PNS) demyelination is a rare clinical entity, more frequently seen in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) multiple sclerosis (MS). This case report showcases patient atypical CIDP CNS lesions. Demographic data, disease course, treatment responsiveness, neurological examination, laboratory tests, nerve conduction studies (NCS), brain spinal cord MRI were registered. The highlights the difficulty of...

10.25122/jml-2022-0010 article EN Journal of Medicine and Life 2022-11-01

Ischemic stroke is one of the leading causes mortality and disability worldwide. Numerous studies were performed to assess risk clinical deterioration acute ischemic patients, including haemorrhagic transformation. The complexity cerebral ischemia pathology raised possibility a multitude candidate-molecules be studied as biomarkers. blood brain barrier integrity biomarkers have shown promising results both in fundamental studies. Matrix metalloproteinases been extensively analysed gave...

10.52418/moldovan-med-j.64-3.21.09 article EN cc-by-sa The Moldovan Medical Journal 2021-10-01

Subarachnoid hemorrhage (SAH) accounts for about 2-7% of all strokes. In 85% cases SAH is caused by an aneurysmal rupture, 10% are non-aneurysmal, non-traumatic, and 5% due to other causes. The risk factors with a major resonance arterial hypertension smoking. purpose the study was analysis factors, clinical course prognosis in patients SAH, which not determined rupture aneurysm or craniocerebral trauma. Methods: were collected during hospitalization Institute Neurology Neurosurgery “Diomid...

10.52692/1857-0011.2021.3-71.01 article EN cc-by Bulletin of the Academy of Sciences of Moldova Medical Sciences 2022-01-01

Introduction. There were no data on in-hospital stroke care indicators until Moldova’s accession to the international Registry of Stroke Care Quality (RES-Q) platform in 2016. The aim this paper was assess acute quality Moldova based RES-Q registry. Material and methods. We analyzed all patients with ischemic hemorrhagic from 15 Moldovan hospitals. Data collected for one month each year, during a 3-year period (2017-2019). analysis performed between hospitals according their access brain CT...

10.52645/mjhs.2022.1.03 article EN Moldovan Journal of Health Sciences 2022-05-01

Transverse myelitis (TM) is a clinical syndrome in which an inflammatory process causes neuronal damage to the spinal cord, leading varying degrees of muscle weakness, sensory changes, and autonomic dysfunction. MT can be form presentation multi-focal CNS disease, multi-systemic, infectious, paraneoplastic, demyelinating, autoimmune or idiopathic disease.The purpose research was analyze cases transverse codes patients treated hospitalized “Diomid Gherman” Institute Neurology...

10.52692/1857-0011.2022.3-74.12 article EN cc-by Bulletin of the Academy of Sciences of Moldova Medical Sciences 2022-12-01

10.5281/zenodo.4527062 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2021-03-01
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