- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Occupational and environmental lung diseases
- Obstructive Sleep Apnea Research
- Respiratory and Cough-Related Research
- Neonatal Respiratory Health Research
- Occupational exposure and asthma
- Cystic Fibrosis Research Advances
- Air Quality and Health Impacts
- Indoor Air Quality and Microbial Exposure
- Advanced Chemical Sensor Technologies
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- Hemodynamic Monitoring and Therapy
- Neuroscience of respiration and sleep
- Atomic and Subatomic Physics Research
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- Delphi Technique in Research
- Tracheal and airway disorders
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- Fibromyalgia and Chronic Fatigue Syndrome Research
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- COVID-19 and healthcare impacts
- Hemispheric Asymmetry in Neuroscience
University of Saskatchewan
2013-2024
Saskatoon Medical Imaging
2021
Primary Source
2020
Isala
2020
Barro Colorado Island
2020
Public Health Agency of Canada
2010
Cincinnati Children's Hospital Medical Center
2009
Visteon (South Korea)
2002
University of British Columbia
1990-2000
National Institute of Neurological Disorders and Stroke
2000
Section:ChooseTop of pageAbstract <<ContentsOverviewIntroductionMethodsThe Patient ExperienceIndicationsRelative Contraindication...Laboratory DetailsHygiene and Infection Con...EquipmentDevice Quality AssuranceOperator DetailsPatient DetailsFEV1 FVC ManeuverBronchodilator Responsive...Reported ValuesGrading the th...VC Inspiratory Capaci...Further StudiesReferencesCITING ARTICLES
This document provides an update to the European Respiratory Society (ERS)/American Thoracic (ATS) technical standards for single-breath carbon monoxide uptake in lung that was last updated 2005. Although both DLCO (diffusing capacity) and TLCO (transfer factor) are valid terms describe of lung, term is used this document. A joint taskforce appointed by ERS ATS reviewed recent literature on measurement surveyed current capabilities instrumentation being manufactured around world. The...
Section:ChooseTop of pageAbstract <<ContentsOverviewIntroductionMethodsReport Format for Spirome...Selecting and Reporting R...Grading the Quality Pu...ConclusionsReferencesCITING ARTICLES
There are numerous reference equations available for the single-breath transfer factor of lung carbon monoxide (T LCO); however, it is not always clear which set should be used in clinical practice. The aim study was to develop Global Lung Function Initiative (GLI) all-age values T LCOData from 19 centres 14 countries were collected define LCO values. Similar GLI spirometry project, derived using LMS (lambda, mu, sigma) method and GAMLSS (generalised additive models location, scale shape)...
This document summarises an update to the European Respiratory Society (ERS)/American Thoracic (ATS) technical standards for single-breath carbon monoxide uptake in lung that was last updated 2005. The full are also available online as https://doi.org/10.1183/13993003.00016-2016 . major changes these relate D LCO measurement with systems using rapidly responding gas analysers and tracer gas, which now most common type of instrumentation being manufactured. Technical improvements increased...
Section:ChooseTop of pageAbstract <<MethodsResuming Outpatient Clini...Specific Pulmonary and Sl...ConclusionsReferencesCITING ARTICLES
To determine whether clinical symptoms and pulmonary function abnormalities were more common in lifetime nonsmoking grain elevator workers exposed to dust than community control subjects who not occupationally dust, we obtained an occupational health questionnaire, spirometric variables, flow-volume curves on 90 subjects. For these groups calculated the prevalence of chronic bronchitis, defined as daily production phlegm for 3 months/yr at least 2 yr. The bronchitis was higher (23.1%) (3.3%)...
Canadian Thoracic Society (CTS) clinical guidelines for asthma and chronic obstructive pulmonary disease (COPD) specify that spirometry should be used to diagnose these diseases. Given the burden of COPD, most people with diseases will diagnosed in primary care setting. The present CTS position statement was developed provide guidance on key factors affecting quality testing may also inform guide accreditation process each province. Although many principles discussed are equally applicable...
In 10 nonasthmatic subjects and 11 patients with asthma, we measured pulmonary resistance (RL), functional residual capacity (FRC), specific conductance (sGaw) before, during, after submaximal treadmill exercise. Nonasthmatic did not change RL, FRC, or sGaw from base-line resting values during RL decreased significantly exercise, both when exercise was begun the control state conditions of elevated a preceding period When asthmatic inhaled standardized dose aerosolized histamine, increase in...
BACKGROUND: An estimated 5.4 million Canadian adults have been diagnosed with sleep apnea or are at high risk of experiencing obstructive (OSA). There no recent data regarding access to and predictors referral for diagnostic testing in these populations. METHODS: The Sleep Apnea Rapid Response survey sampled 8647 captured information about risk, testing, diagnosis treatment apnea. Predictors laboratory test referrals were assessed using log‐linked binomial regression modelling. Information...
We conducted a prospective study to evaluate whether lack of an adequate increase in diffusing capacity for carbon monoxide (Dl CO) during exercise is associated with greater postoperative complication rate after lung resection. used the three-equation method (3EQ-Dl CO), modification single breath Dl CO technique determine 57 patients undergoing resection at Vancouver General Hospital from October 1998 May 1999. 3EQ-Dl was determined steady-state 35% and 70% maximal workload reached...
The single-breath diffusing capacity of the lung for CO [DLCO(SB)] is considered a measure conductance across alveolar-capillary membrane and its binding with hemoglobin. Although incomplete mixing inspired gas alveolar could theoretically influence overall diffusion, conventional calculations DLCO(SB) spuriously overestimate during short breath-holding periods when within might have greatest effect. Using three-equation method to calculate which analytically accounts changes in breath-hold...
Using three conventional methods and a new method we measured the single-breath diffusing capacity for carbon monoxide [DLCO(SB)] in group of normal subjects. Whereas calculated DLCO(SB) from single equation valid only breath holding, used equations, one each phase maneuver, i.e., inhalation, exhalation. We found that while calculating were greatly affected by variations way which maneuver was performed and/or alveolar gas sample collected, these had little effect on calculations using...
It has been previously shown that conventional methods of measuring the single-breath diffusing capacity lung for carbon monoxide (DLCOsb) overestimate diffusion in normal subjects when expiratory flow rate is reduced, collection exhaled alveolar gas sample delayed, and/or too large an collected. Conventional use a single breathholding equation to analyze entire maneuver, which consists inhalation, breathholding, and exhalation. We developed method calculating DLCOsb using 3 separate...
We used a computerized lung model to examine methods of measuring the single breath diffusing capacity for carbon monoxide (DLCOSB). Although maneuver consists inhalation, holding, and exhalation, current DLCOSB use one equation that is accurate only they attempt correct effects inhalation exhalation using rigidly standardized procedure. Using uniform model, we verified variations in performing standarized alveolar gas sampling, which frequently occur practice, cause wide variability...
Although carboxyhemoglobin (COHb) is often increased in smokers, American Thoracic Society recommendations for adjusting the single breath carbon monoxide (CO) diffusing capacity (DlCOSB) COHb remain optional. Using a previously described 3-equation technique, we measured DlCOSB and an index of diffusion inhomogeneity (DI) 10 healthy, nonsmoking subjects who performed maneuvers both before after increasing COHb. CO backpressure (FaCO) was from exhaled gas standardized deep room air that...