A5032279899- Advanced Data Storage Technologies
- Distributed and Parallel Computing Systems
- Scientific Computing and Data Management
- Research Data Management Practices
- Cell Image Analysis Techniques
- Animal Genetics and Reproduction
- Developmental Biology and Gene Regulation
- Parallel Computing and Optimization Techniques
- Advanced Fluorescence Microscopy Techniques
- Advanced Database Systems and Queries
- Single-cell and spatial transcriptomics
- Big Data Technologies and Applications
- Medical Imaging Techniques and Applications
- Cerebral Venous Sinus Thrombosis
- Intraoperative Neuromonitoring and Anesthetic Effects
- Environmental Monitoring and Data Management
- Corneal Surgery and Treatments
- Image Processing and 3D Reconstruction
- Optical measurement and interference techniques
- Advanced X-ray Imaging Techniques
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Congenital Ear and Nasal Anomalies
- Zebrafish Biomedical Research Applications
- bioluminescence and chemiluminescence research
- Retinal and Macular Surgery
Kentucky imaging Technologies (United States)
2021
Karlsruhe Institute of Technology
2010-2020
University of Illinois Urbana-Champaign
2015
FZI Research Center for Information Technology
2004
Abstract A new era in developmental biology has been ushered by recent advances the quantitative imaging of all-cell morphogenesis living organisms. Here we have developed a light-sheet fluorescence microscopy-based framework with single-cell resolution for identification and characterization subtle phenotypical changes millimeter-sized Such comparative study requires analyses entire ensembles to be able distinguish sample-to-sample variations from definitive changes. We present kinetic...
Cranial neural crest (NC) contributes to the developing vertebrate eye. By multidimensional, quantitative imaging, we traced origin of ocular NC cells two distinct populations that differ in maintenance sox10 expression, Wnt signalling, origin, route, mode and destination migration. The first population migrates proximal second cell group populates distal (anterior) part analysing zebrafish pax6a/b compound mutants presenting anterior segment dysgenesis, demonstrate Pax6a/b guide...
Data from high-energy physics (HEP) experiments are collected with significant financial and human effort mostly unique. An inter-experimental study group on HEP data preservation long-term analysis was convened as a panel of the International Committee for Future Accelerators (ICFA). The formed by large collider-based investigated technical organisational aspects preservation. intermediate report released in November 2009 addressing general issues HEP. This paper includes extends report. It...
The Large Scale Data Facility (LSDF) at the Karlsruhe Institute of Technology was started end 2009 with aim supporting growing requirements data intensive experiments. In close cooperation involved scientific communities, LSDF provides them not only adequate storage space but a directly attached analysis farm and - more importantly value added services for their big data-sets. Analysis workflows are supported through mixed Hadoop Open Nebula Cloud environments to storage, enable efficient...
To cope with the growing requirements of data intensive scientific experiments, models and simulations Large Scale Data Facility(LSDF) at KIT aims to support many disciplines. The LSDF is a distributed storage facility Exabyte scale providing storage, archives, bases meta repositories. Open interfaces APIs variety access methods highly available services for high throughput applications. Tools an easy transparent allow scientists use without bothering internal structures technologies. In...
To cope with the growing requirements of data intensive scientific experiments, models and simulations Large Scale Data Facility (LSDF) at KIT aims to support many disciplines. The LSDF is a distributed storage facility Exabyte scale providing storage, archives, bases meta repositories. Apart from communities need perform processing operations as well. For this purpose Execution Framework for Intensive Applications (LAMBDA) was developed allow asynchronous high-performance next LSDF....
The Large Scale Data Facility (LSDF) was conceived and launched at the Karlsruhe Institute of Technology (KIT) end 2009 to address growing need for value-added storage services data intensive experiments. LSDF main focus is support scientific experiments producing large sets reaching into petabyte range with adequate storage, value added management, processing preservation. In this work we describe approach taken perform analysis in LSDF, as well management datasets.
Many experiments have a data-management problem!This project aims at improving the situation,
In many sciences the increasing amounts of data are reaching limit established handling and processing. With four large research centers German Helmholtz association Large Scale Data Management Analysis (LSDMA) project supports an initial set scientific projects, initiatives instruments to organize efficiently analyze amount produced in modern science. LSDMA bridges gap between production analysis using a novel approach by combining specific community support generic, cross development. Life...
Abstract New imaging techniques enable visualizing and analyzing a multitude of unknown phenomena in many areas science at high spatio-temporal resolution. The rapidly growing amount image data, however, can hardly be analyzed manually and, thus, future research has to focus on automated analysis methods that allow one reliably extract the desired information from large-scale multidimensional data. Starting with infrastructural challenges, we present new software tools, validation benchmarks...
In this paper, the method of data intensive computing is studied for large amounts in computed tomography (CT). An automatic workflow built up to connect beamline ANKA with scale facility (LSDF), able enhance storage and analysis efficiency. workflow, paper focuses on parallel 3D reconstruction. Different from existing reconstruction system filtered back-projection method, an algebraic technique based compressive sampling theory presented reconstruct ultrafast fewer projections. Then...
In vivo confocal microscopy of the corneal subbasal nerve plexus and assessment its morphology promises to provide a novel, highly sensitive tool for early diagnosis therapy monitoring diabetic peripheral neuropathy.Ridge-like tissue deformations in region plexus, induced by pressure upon surface, can prevent imaging sub-basal nerves over entire field view impede morphology.We present an investigation distribution deformation heights, yielding mean value 28.9 µm our data.Given depth focus...
After analysis and publication, there is no need to keep experimental data online on spinning disks. For reliability costs inactive moved tape put into a archive. The archive must provide reliable access for at least ten years following recommendation of the German Science Foundation (DFG), but many scientific communities wish available much longer. Data archival one hand purely bit preservation activity in order ensure bits read are same as those written before. On other enough information...