A5083259889- Obesity, Physical Activity, Diet
- Adipose Tissue and Metabolism
- Health and Lifestyle Studies
- Vitamin D Research Studies
- Telomeres, Telomerase, and Senescence
- Nutritional Studies and Diet
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Health and Risk Factors
- Nutrition, Genetics, and Disease
- Fibroblast Growth Factor Research
- Global Public Health Policies and Epidemiology
- Exercise and Physiological Responses
- Textile materials and evaluations
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- GDF15 and Related Biomarkers
- Growth Hormone and Insulin-like Growth Factors
- Apelin-related biomedical research
- Nutrition and Health in Aging
- Public Health and Nutrition
- Bone and Dental Protein Studies
- Obesity and Health Practices
Panagiotis & Aglaia Kyriakou Children's Hospital
2024
National and Kapodistrian University of Athens
2019-2024
Overweight and obesity in childhood adolescence represent major public health problems of our century, account for increased morbidity mortality adult life. Irisin Fibroblast Growth Factor 21 (FGF-21) have been proposed as prognostic and/or diagnostic biomarkers subjects with metabolic syndrome, because they increase earlier than other traditional biomarkers. We determined the concentrations FGF-21 children adolescents overweight before after one year a life-style intervention program diet...
The adipose and bone tissues demonstrate considerable interconnected endocrine function. In the present study, we determined concentrations of fibroblast growth factor-23 (FGF-23), osteopontin, neutrophil gelatinase-associated lipocalin (NGAL) sclerostin in 345 children adolescents who were overweight or obese (mean age ± SD mean: 10.36 0.16 years; 172 males, 173 females; 181 prepubertal; 164 pubertal) before after their participation a comprehensive life-style intervention program diet...
Obesity in childhood and adolescence is associated with complications that resemble those seen hypercortisolism. Hair cortisol concentration (HCC) children a reliable marker of long-term endogenous concentrations. We determined HCC overweight obese adolescents, examined the relation between other cardiometabolic parameters.Three hundred adolescents aged 4-18 years (mean age ± standard error mean [SEM]: 10.49 0.15 years; 140 [46.7%] obese, 94 [31.3%] overweight, 66 [22%] normal BMI; 76 males,...
<b><i>Background:</i></b> Obesity in childhood and adolescence represents a major health problem of our century. In Greece, 30–35% children adolescents are overweight or obese. <b><i>Objective Hypotheses:</i></b> To investigate the effectiveness comprehensive multidisciplinary personalized management plan at reducing prevalence obesity adolescence. <b><i>Patients Methods:</i></b> One thousand (<i>n</i> =...
Leucocyte telomere length (LTL) is a robust marker of biological aging and associated with obesity cardiometabolic risk factors in childhood adolescence. We investigated the effect structured, comprehensive, multidisciplinary, personalized, lifestyle intervention program healthy diet physical exercise on LTL 508 children adolescents (239 males, 269 females; 282 prepubertal, 226 pubertal), aged 10.14 ± 0.13 years. Participants were classified as obese (n = 267, 52.6%), overweight 174, 34.2%),...
Obesity in childhood and adolescence represents one of the most challenging public health problems 21st century owing to its epidemic proportions worldwide associated significant morbidity, mortality costs. In Greece, prevalence overweight obesity exceeds 30–35%. To address increasing children adolescents our country, we developed ‘National e-Health Program for Prevention Management Overweight Childhood Adolescence’, which provides specific detailed guidance all primary care physicians about...
In adults, short leukocyte telomere length (LTL) is associated with metabolic disorders, such as obesity and diabetes mellitus type 2. These associations could stem from early life interactions between LTL disorders. To test this hypothesis, we explored the parameters well their evolution over time in children or without at baseline. Seventy-three (n = 73) attending our Outpatient Clinic for Prevention Management of Overweight Obesity Childhood Adolescence, aged 2–10 years (mean ± SD: 7.6...
Background: Obesity in childhood and adolescence has reached epidemic proportions recent decades. Methods: In the present study, we determined concentrations of apelin-12, vaspin resistin 106 children adolescents with overweight or obesity before after implementation a multidisciplinary, personalized lifestyle intervention program diet, sleep exercise for 1 year. All subjects attended our Center Prevention Management Overweight Childhood Adolescence. Results: Following intervention, there...