A5101505170- Cancer Cells and Metastasis
- Blood properties and coagulation
- Cancer-related Molecular Pathways
- Hedgehog Signaling Pathway Studies
- Organ Transplantation Techniques and Outcomes
- Cancer, Stress, Anesthesia, and Immune Response
- Abdominal vascular conditions and treatments
- Renal and Vascular Pathologies
- Wnt/β-catenin signaling in development and cancer
Erasmus University Rotterdam
2013
Meertens Institute
2010
Erasmus MC
2010
Universidade do Porto
1978
Wnt signaling plays a central role in mammary stem cell (MaSC) homeostasis and breast cancer. In particular, epigenetic alterations at different members of the pathway have been identified among triple-negative, basal-like cancers. Previously, we developed mouse model for metaplastic adenocarcinoma, subtype triple-negative cancer, by targeting hypomorphic mutations endogenous Apc gene (Apc1572T/+). Here, employing CD24 CD29 surface antigens, subpopulation cancer cells (MaCSCs) from...