- Marine and coastal ecosystems
- Ocean Acidification Effects and Responses
- Microbial Community Ecology and Physiology
- Marine Bivalve and Aquaculture Studies
- Circadian rhythm and melatonin
- Frailty in Older Adults
- Sleep and related disorders
- Allergic Rhinitis and Sensitization
- Plant and animal studies
- Nutrition and Health in Aging
- Diabetes Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Marine Biology and Ecology Research
- Diabetes and associated disorders
- Diet and metabolism studies
- Sleep and Wakefulness Research
- Geriatric Care and Nursing Homes
- Species Distribution and Climate Change
- COVID-19 epidemiological studies
- Health, Environment, Cognitive Aging
- Insect and Arachnid Ecology and Behavior
- Influenza Virus Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes Management and Research
- Aquatic Ecosystems and Phytoplankton Dynamics
Helmholtz Centre for Environmental Research
2020-2025
German Centre for Integrative Biodiversity Research
2020-2025
Leibniz Institute of Freshwater Ecology and Inland Fisheries
2013-2023
Berlin Center for Genomics in Biodiversity Research
2023
Louis Stokes Cleveland VA Medical Center
2006-2019
Geriatric Research Education and Clinical Center
2006-2017
Case Western Reserve University
2003-2017
National Center for Immunization and Respiratory Diseases
2017
Centers for Disease Control and Prevention
2017
Rensselaer Polytechnic Institute
2015
Over the past 20 years, both inpatient units and outpatient clinics have developed programs for geriatric evaluation management. However, effects of these interventions on survival functional status remain uncertain.
Background: Light therapy has shown great promise as a nonpharmacological method to improve symptoms associated with Alzheimer’s disease and related dementias (ADRD), preliminary studies demonstrating that appropriately timed light exposure can nighttime sleep efficiency, reduce nocturnal wandering, alleviate evening agitation. Since the human circadian system is maximally sensitive short-wavelength (blue) light, lower, more targeted lighting interventions for therapeutic purposes, be used....
Significance Coexposure to airborne pollen enhances susceptibility respiratory viral infections, regardless of the allergy status. We hypothesized this could be also true for SARS-CoV-2 infections. To investigate this, we tested relationships between infection rates and concentrations, along with humidity, temperature, population density, lockdown effects. Our unique dataset derives from 130 sites in 31 countries across five continents. found that pollen, sometimes synergy humidity...
Every year, the oceans absorb about 30% of anthropogenic carbon dioxide (CO2) leading to a re-equilibration marine carbonate system and decreasing seawater pH. Today, there is increasing awareness that these changes-summarized by term ocean acidification (OA)-could differentially affect competitive ability organisms, thereby provoking restructuring ecosystems biogeochemical element cycles. In winter 2013, we deployed ten pelagic mesocosms in Gullmar Fjord at Swedish west coast order study...
Upregulation of pro-inflammatory cytokines has not only been associated with increased morbidity and mortality in older adults but also linked to frailty. In the current study we aimed compare relative relationship age frailty on inflammation thrombosis veterans. We analyzed 117 subjects (age range 62–95 years; median 81) divided into 3 cohorts: non-frail, pre-frail frail based Fried phenotype Serum inflammatory markers were determined using commercially available ELISA kits. Frail (PF) had...
Summary Pollen grain size relates to plant community structure via pollen dispersal, resource allocation into regenerative processes, phylogeny and genetics (ploidy), or it can be used as a decisive trait for species distinction. However, the availability of data is limited because labor‐ time‐consuming methodological constraints classically based on fewer than 50 measured grains per species, thus restricting our knowledge temporal spatial variability in response biotic abiotic conditions....
The oceans absorb ~25% of the annual anthropogenic CO2 emissions. This causes a shift in marine carbonate chemistry termed ocean acidification (OA). OA is expected to influence metabolic processes phytoplankton species but it unclear how combination individual physiological changes alters structure entire communities. To investigate this, we deployed ten pelagic mesocosms (volume ~50 m3) for 113 days at west coast Sweden and simulated (pCO2 = 760 μatm) five them while other served as...
Abstract. Dissolved organic carbon (DOC) concentrations – mainly of terrestrial origin are increasing worldwide in inland waters. Heterotrophic bacteria the main consumers DOC and thus determine temporal dynamics availability for higher trophic levels. Our aim was to study bacterial (C) turnover with respect quantity chemical quality using both allochthonous autochthonous sources. We incubated a natural community C (13C-labeled beech leachate) increased pulses (intermittent occurrence matter...
Summary Pollen identification and quantification are crucial but challenging tasks in addressing a variety of evolutionary ecological questions (pollination, paleobotany), also for other fields research (e.g. allergology, honey analysis or forensics). Researchers exploring alternative methods to automate these but, several reasons, manual microscopy is still the gold standard. In this study, we present new method pollen using multispectral imaging flow cytometry combination with deep...
Abstract Lakes worldwide are affected by multiple stressors, including climate change. This includes massive loading of both nutrients and humic substances to lakes during extreme weather events, which also may disrupt thermal stratification. Since multi‐stressor effects vary widely in space time, their combined ecological impacts remain difficult predict. Therefore, we two consecutive large enclosure experiments with a comprehensive time‐series broad‐scale field survey unravel the...
Abstract Aims To describe light exposure, sleep–wake patterns, mood, pain and their relationships in adult medical inpatients. Background The hospital environment may contribute to patient discomfort by providing a lighting structure that interferes with circadian rhythmicity, sleep, mood pain. Design A descriptive correlational design was used this preliminary study. Methods Between May 2011–April 2012, data were collected from convenience sample of 23 women 17 men admitted large...
Abstract. The oceans absorb about a quarter of the annually produced anthropogenic atmospheric carbon dioxide (CO2), resulting in decrease surface water pH, process termed ocean acidification (OA). Surprisingly little is known how OA affects physiology heterotrophic bacteria or coupling to phytoplankton when nutrients are limited. Previous experiments were, for most part, undertaken during productive phases following nutrient additions designed stimulate algal blooms. Therefore, we performed...
In aquatic systems, terrestrial dissolved organic matter (t‐DOM) is known to stimulate bacterial activities in the water column, but simultaneous effects of autumnal leaf input on column and sediment microbial dynamics littoral zones lakes remain largely unknown. The study's objective was determine litter metabolism sediment, subsequently, consequences for carbon cycling food web dynamics. Therefore, late fall, we simultaneously measured zone a temperate shallow lake after adding particulate...
The absence of daily robust light-dark exposure patterns may contribute to sleep disturbances in persons with Alzheimer’s disease and related dementias (ADRD). Personal activity-rest were measured for healthy older adults ADRD. Persons ADRD experienced lower light levels, exhibited activity had greater levels circadian disruption than during winter. Seasonal differences observed ADRD; seen the winter summer, although did not differ two seasons.
Abstract Background In plants and animals, pollen or sperm morphology differ greatly between species. Across plant species, morphological diversity is broadly linked to different pollination systems. However, the extent of within-species less well understood. To address this question, we explored anther in rye ( Secale cereale L.), a wind-pollinating grass Results We analysed 339 domesticated, feral wild individuals 64 diverse accessions. Population structure analysis revealed...
ABSTRACT Artificial intelligence (AI) surpasses human accuracy in identifying ordinary objects, but it is still challenging for AI to be competitive pollen grain identification. One reason this gap the extensive trait variation grains. In classical textbooks, size relies on only 25–50 grains, mostly one plant and site. Lack of databases can cause limited application machine learning approaches real‐world samples. Therefore, our study aims investigate sources spatial temporal morphology...
The care of elderly patients with diabetes should be individualized, taking into account the patient's comorbidities, other medications, cognitive abilities, home situation, and life expectancy. Especially in frail, patients, there less emphasis on strict glycemic control than avoiding malnutrition hypoglycemia achieving best quality possible.
ABSTRACT Both preexisting immunity to influenza and age have been shown be correlates of vaccine responses. Frailty, an indicator functional impairment in older adults, was also one study predict lower responses among nonveterans. In the current study, we aimed determine associations between frailty, immunity, immune veterans. We studied 117 subjects (age range, 62 95 years [median age, 81 years]), divided into three cohorts based on Fried frailty test, i.e., nonfrail (NF) ( n = 23 68...
The SARS-CoV-2 pandemic co-occurred with pollen season in Europe 2020 and recent studies suggest a potential link between both. Air samples collected at our measuring station Leipzig purified were analyzed for typical signals or virus-induced cytopathic effects, to test if the virus could bind bioaerosols so, whether these complexes are infectious. results show that neither air nor infectious act as carrier particles.
Societal Impact Statement Pollen relates to many aspects of human and environmental health, which protection improvement are endorsed by the United Nations Sustainable Development Goals. By highlighting these connections in frame current challenges monitoring research, we discuss need more integrative multidisciplinary pollen research related societal needs, improving health humans our ecosystems for a sustainable future. Summary is at once intimately part reproductive cycle seed plants...
Aim Frailty is a common phenomenon in geriatric patients. In the present translational research study, we assessed two frailty instruments ( F ried 2001; G ill 2002), comparing usefulness and scoring classifications for screening an academically affiliated geriatrics clinic. Methods Assessment was completed on 162 male veterans (mean age 83.7 years, 57% A frican merican) enrolled The instruments' component criteria, which are well known to gerontological clinicians, were administered...
Numerous non-pharmacological programs for family caregivers and persons with dementia (PWDs) have been found efficacious in randomized controlled trials. Few tested translation studies that assess feasibility outcomes less-controlled, real-world implementations. This study the impact of partnership version BRI Care Consultation, "Partners Dementia (PDC)," on PWDs their family/friend caregivers. PDC was delivered via partnerships between Louis Stokes Department Veterans Affairs Medical Center...