Background Involving pre-sampled patients with cholecystitis, dysplasia, and adenocarcinoma, the present study aimed to compare neutrophil/lymphocyte (NLR), monocyte/lymphocyte (MLR), platelet/lymphocyte (PLR) ratios, plateletcrit (PCT), mean platelet volume (MPV), distribution width (PDW) values determine their prognostic importance. Methods The involved 187 cholecystectomy specimens that were diagnosed as adenocarcinoma. Preoperative neutrophil, monocyte, lymphocyte, counts, NLR, MLR, PLR...

Coronavirus disease 2019 (COVID-19) patients are predisposed to thrombotic events. COVID-19 coagulopathy can be associated with ADAMTS-13 (a disintegrin-like and metalloprotease thrombospondin type I repeats 13) levels. ADAMTS-13, the cleaving protease of highly thrombogenic ultra-large von Willebrand Factor (vWF) multimers, was rarely investigated in inconsistent results were obtained. We measured levels admitted emergency department.

The signaling pathway OPG/RANK/RANKL is a key in maintaining the balance between activity of osteoblasts and osteoclasts order to prevent bone loss. In this study, our aim was assess effects long-term nicotine exposure on plasma RANKL OPG levels, tissue immunoreactivities, mineral density (BMD) scores rats.Thirty-six Swiss Albino rats weighing 70 ± 10 g were divided into three groups. While controls (n = 12) only given normal drinking water, for low-dose (LDN) group 0.4 mg/kg/day; high-dose...

<b>Background:</b> Most women do not stop smoking either during pregnancy or in the lactation period. This study was carried out to investigate effect of long term per oral pre/postnatal low/high dose nicotine exposure on fetal plasma/tissue oxidant-antioxidant status rats. <b>Methods:</b> The groups were composed pups whose parents used did use and divided into 3 groups, each consisting 10 rats; control group (normal drinking water), low high according (0.4 mg/kg 6.0 BW/day, respectively)...

Substance analyzes are carried out to determine drug use. There is a workflow plan that should apply for use tests medico-legal purposes. The most important thing about this the preservation of urinary integrity.

Nodular formation of thyroid tissue is a very common endocrinologic pathology. Approximately 5% nodules can prove to be cancerous. The usefulness mean platelet volume(MPV) and neutrophil lymphocyte ratio (NLR) determined as an indicator immunological response subclinical inflammation in recent years. In this study we evaluate the association stimulating hormone (TSH), platelet, NLR levels between that turn into cancer do not convert. Our consisted patients with converted (n = 100) didn’t...

AbstractBackground Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders in which the underlying pathogenesis and etiologic factors are not fully understood. The blood brain barrier (BBB) ​​plays critical role central nervous system defense by limiting access to circulating solutes, macromolecules, cells that can negatively affect neuronal activity. loss BBB integrity likely be seen as common pathologic finding for many psychiatric such schizophrenia, ASD, mood disorders....

To investigate the effect of nicotine exposure starting before coitus and continuing during pregnancy lactation period on delivery rate, fetal growth addiction in rats.Ten female Swiss Albino rats were divided into 2 groups as group (NG) (n=5), control conceived by adding male to each group. While was given only normal drinking water, 0.4 mg/kg body weight (BW)/day NG water. After delivery, BWs pups recorded weekly for 6 weeks their water preferences assessed. Meanwhile, continued receive...

The roles of bun/d-dimer and bun/lactate ratios in intensive care patients with COVID-19The

Nicotine is one of the main chemicals in cigarettes responsible for addiction formation. Many researches investigating effects nicotine on coronary heart disease and atherosclerosis have been published. The robustness endothelial cells very important development atherosclerosis. aim this study to evaluate effect exposure indicators function either by examining vascular reactivity aorta taken from rats exposed during prenatal (starting mating period) postnatal periods (6 weeks after...

Various pharmacological doses of nicotine during gestation have been examined and exposure alone is expected to be less harmful the fetus than cigarette smoke. Nicotine affects neurochemical systems. Neurotrophins are very important factors for neuronal development, plasticity neurons.

Background and Aims: Blood collection tubes (BCT) with gel separators are diagnostic devices that can affect all laboratory processes. In this study, the aim was to compare performance of a new brand BCT sample well-known widely used in market. Materials Methods: samples were taken from 50 healthy volunteers two brands BCTs (KWS BD Vacutainer SST II Advance) by providing standard conditions. The nine most requested test parameters determined analyzed simultaneously. results using SPSS 21...

Introduction: A previous study has evaluated the association between serum tumour necrosis factor-like weak apoptosis inducer (TWEAK) levels and autism spectrum disorder (ASD). In line with this investigation, present aimed to measure TWEAK determine whether their eventual alteration might have etiopathogenetic significance in children ASD. Methods: total of 40 treatment-naive ASD healthy as controls were included study. The Schedule for Affective Disorders Schizophrenia School-Aged...

Colorectal cancer (CRC) is a leading cause of death worldwide. The main precursor lesion to CRC the adenomatous colorectal polyp (CP). Nowadays, there no recognized perfect screening test CP and CRC. Neopterin an important marker cellular inflammation. In this study, we aimed evaluate comparatively immunochromatographic fecal occult blood (iFOBT) neopterin levels (FNLs) in patients with controls.One hundred eleven diagnosed 68 individuals negative colonoscopy were included study. iFOBT FNLs...

Amaç: Son zamanlarda yayınlanan bazı makaleler yanlış pozitif human koryonik gonadotropin (hCG) sonuçlarının kaynağını araştırmıştır. Bu olgu, kronik böbrek hastalığı (KBH) olan genç bir kadın hastada hafif yüksek gerçek hCG sonucunu göstermektedir. Gereç ve Yöntem: Hastanın serum değeri 4 immunoassay sistemi ile ölçüldü. Daha sonraki aşamada dilüsyon PEG 6000 çöktürme gerçekleştirildi. Bulgular: yöntemi ilede sonuçları miktar bulundu. Immulite geri kazanım oranı sonucu için 0,98, 0,54...

Nicotine, is an alkaloid compound consisting of pyridine and pyrolidine ring. Its closed formula C10H4N2. During smoking peak plasma concentration changes from 25 to 50 ng/mL. half-life 1–2 h. Nicotine metabolized primarily in the liver excreted by kidneys. The nicotine metabolite cotinine 10 times more than its longer around 15 20 Cotinine can be found both amniotic fluid umbilical cord blood given that it passes across placental barrier. Adverse effects metabolites on fetus are suggested...