- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Advanced Neuroimaging Techniques and Applications
- Breast Lesions and Carcinomas
- Medical Imaging Techniques and Applications
- Breast Cancer Treatment Studies
- AI in cancer detection
- Lanthanide and Transition Metal Complexes
- Digital Radiography and Breast Imaging
- Medical Imaging and Analysis
Kyoto University
2016-2024
Skåne University Hospital
2022-2024
Lund University
2022-2024
Kyoto Medical Center
2020-2022
Purpose To investigate the performance of integrated approaches that combined intravoxel incoherent motion (IVIM) and non-Gaussian diffusion parameters compared with Breast Imaging Reporting Data System (BI-RADS) to establish multiparameter thresholds scores or probabilities by using Bayesian analysis distinguish malignant from benign breast lesions their correlation molecular prognostic factors. Materials Methods Between May 2013 March 2015, 411 patients were prospectively enrolled 199...
Background Ultrafast dynamic contrast‐enhanced (UF‐DCE) breast MRI is considered a promising method of accelerated MRI. However, the value new kinetic parameters derived from UF‐DCE need clinical evaluation. Purpose To evaluate diagnostic performance maximum slope (MS), time to enhancement (TTE), and interval between arterial venous visualization (AVI) using compressed sensing (CS). Study Type Retrospective. Population Seventy‐five patients with histologically proven lesions. The total...
Introduction The aim of this study was to investigate the variation apparent diffusion coefficient (ADC) values with time according breast tumor type and prognostic biomarkers expression. Materials Methods A total 201 patients known or suspected tumors were prospectively enrolled in study, 132 (86 malignant 46 benign) analyzed. Diffusion-weighted imaging scans 2 times acquired on a clinical 3-T magnetic resonance scanner using oscillating pulsed diffusion-encoding gradients (effective times,...
We aimed to investigate the performance of high resolution-diffusion-weighted imaging (HR-DWI) using readout-segmented echo-planar in visualizing malignant breast lesions and evaluating their extent, pathology as a reference.This retrospective study included patients who underwent HR-DWI with surgically confirmed lesions. Two radiologists blinded final diagnosis evaluated independently identified lesions, measuring maximum diameters. Another radiologist if those were identical pathology. The...
Ultrafast (UF) dynamic contrast-enhanced (DCE)-MRI offers the potential for a faster and, therefore, less expensive examination of breast lesions; however, there are no reports that have evaluated whether UF DCE-MRI can be used same as conventional in reading morphological information. This study agreement information obtained from malignant mass lesions between and DCE-MRI. data were over first 60 s post-contrast injection, followed by DCE images. Two readers size morphology final phase...
We prospectively examined the variability of non-Gaussian diffusion magnetic resonance imaging (MRI) and intravoxel incoherent motion (IVIM) measurements with different numbers b-values excitations in normal breast tissue lesions. Thirteen volunteers fourteen patients lesions (seven malignant, eight benign; one patient had bilateral lesions) were recruited this prospective study (approved by Internal Review Board). Diffusion-weighted MRI was performed 16 (0–2500 s/mm2 number [NEX]) five...
To investigate whether intravoxel incoherent motion (IVIM) and/or non-Gaussian diffusion parameters are associated with distant disease-free survival (DDFS) in patients invasive breast cancer.From May 2013 to March 2015, 101 (mean age 60.0, range 28-88) cancer were evaluated prospectively. IVIM (flowing blood volume fraction [fIVIM] and pseudodiffusion coefficient [D*]) (theoretical apparent [ADC] at a b value of 0 s/mm2 [ADC0] kurtosis [K]) estimated using diffusion-weighted imaging series...
This study aimed to evaluate the MRI findings of breast solitary masses in diagnostic procedures decide appropriate category based on American College Radiology (ACR) BI-RADS-MRI 2013, with focus lesion size.A retrospective review 2,603 consecutive reports identified 250 pathologically-proven masses. Dynamic-contrast enhanced images and diffusion-weighted were performed a 3.0/1.5 Tesla Scanner 16/4 channel dedicated coil. re-evaluated according ACR 2013. descriptors, size minimum apparent...
The purpose of this study was to investigate the diagnostic performance ultrafast DCE (UF-DCE) MRI after completion neoadjuvant systemic therapy (NST) in breast cancer. In study, MR examinations 55 post-NST cancers were retrospectively analyzed. Residual tumor sizes measured 20th phase UF-DCE MRI, early and delayed phases conventional high spatial-resolution CE (UF, early, delayed, HR, respectively). for detection residual invasive cancer calculated by ROC analysis. size difference between...
The purpose of this study is to investigate the prediction Ki-67 expression breast cancers using MRI parameters from ultrafast (UF) DCE-MRI, DWI, T2WI, and lesion size. Breast was performed with a 3T scanner dedicated coils. UF DCE-MRI obtained Compressed Sensing-VIBE (prototype sequence). As kinetic parameter maximum slope (MS) defined as percentage relative enhancement (%/s), time enhance (TTE) interval between aorta enhancement. apparent diffusion coefficient (ADC) derived DWI. Two...
Digital breast tomosynthesis (DBT) has become a standard screening tool for cancer. However, its diagnostic performance is still limited compared to contrast-enhanced MRI, especially in women with dense breasts. Ultrafast dynamic (UF DCE) MRI and diffusion-weighted imaging (DWI) offer shorter scanning time than conventional have shown promise previous studies. few reports explored the added value of UF DCE-MRI DWI on DBT diagnosing lesions. This study aimed assess abbreviated using DBT. The...