- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Neonatal Health and Biochemistry
- Child Nutrition and Water Access
- Folate and B Vitamins Research
- Prenatal Screening and Diagnostics
Fundação Faculdade de Medicina
2024
Universidade Federal de Minas Gerais
2014-2021
To characterize the deaths of 193 children with sickle cell disease screened by a neonatal program from 1998 to 2012 and contrast initial years final years. Deaths were identified active surveillance absent scheduled appointments in Blood Bank Clinical Centers (Hemominas). epidemiological data came death certificates, screening database, medical records, family interviews. Between 2012, 3,617,919 2,591 had (1:1,400). There (7.4%): 153 SS/Sβ0-talassemia, 34 SC 6 Sβ+thalassemia; 76.7% younger...
To characterize the deaths of 193 children with sickle cell disease screened by a neonatal program from 1998 to 2012 and contrast initial years final years. Deaths were identified active surveillance absent scheduled appointments in Blood Banks. Clinical epidemiological data came death certificates, screening database, medical records, family interviews. Between 2012, 3,617,919 2,591 had (1:1,400). There (7.4%): 153 SS/Sβ0‐talassemia, 34 SC 6 Sβ+thalassemia; 76.7% younger than five years;...
BackgroundChildren in developing countries with sickle cell disease SCD have high rates of mortality, especially some parts Africa.AimTo compare the 5-year estimated mortality rate children born between 1999 and 2001 that 2009 2011.MethodsDuring period 1998–2012, was diagnosed 2591 3,617,919 newborns screened Minas Gerais, Brazil (1 : 1,400). The probability death [1 - Survival] calculated by Kaplan–Meier method. logrank test used to groups survival data.ResultsOf 2576 (15 were excluded),...
Stroke is a serious complication of sickle cell anemia (SCA). The transcranial Doppler (TCD) the risk-screening tool for ischemic strokes. objective study was to describe clinical progression children with SCA who presented high risk stroke by TCD or relevant changes magnetic resonance angiography (MRA) and underwent regular transfusion program (RTP) and/or hydroxyurea (HU) treatment between 2007 2018.This neonatal retrospective/prospective cohort born 1999 2014 homozygotic form (HbSS)...
Background: Stroke is a serious complication of sickle cell anemia (SCA). Transcranial Doppler (TCD) the risk screening tool for ischemic strokes. Objective: The objective study was to describe clinical progression children with SCA who presented high stroke by TCD or relevant changes magnetic resonance angiography (MRA) and underwent regular transfusion program (RTP) and/or hydroxyurea (HU) treatment between 2007 2018. Method: This neonatal retrospective/prospective cohort born 1999 2014...