A5082410315- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Medical Imaging and Pathology Studies
- Inhalation and Respiratory Drug Delivery
- Sarcoidosis and Beryllium Toxicity Research
- Allergic Rhinitis and Sensitization
- Rheumatoid Arthritis Research and Therapies
- Cystic Fibrosis Research Advances
- Tracheal and airway disorders
- Systemic Sclerosis and Related Diseases
- Immunodeficiency and Autoimmune Disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Tuberculosis Research and Epidemiology
- Neonatal Respiratory Health Research
- Mycobacterium research and diagnosis
- Transplantation: Methods and Outcomes
- Pulmonary Hypertension Research and Treatments
- Urinary Tract Infections Management
- Infectious Diseases and Tuberculosis
- Airway Management and Intubation Techniques
- Occupational and environmental lung diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Effects of Exercise
- Respiratory Support and Mechanisms
University of Aberdeen
2011-2024
Aberdeen Royal Infirmary
2010-2022
NHS Grampian
2014-2018
British Thoracic Society
2016
New Cross Hospital
2014
Aberdeen Regional Hospital
2014
Warwickshire Hospital
2014
Coventry (United Kingdom)
2014
St Helens Hospital
2014
Roche (United Kingdom)
2014
Global spread of aggressive mycobacteria Many mycobacteria, in addition to those causing leprosy and tuberculosis, are capable infecting humans. Some can be particularly dangerous patients suffering from immunosuppression or chronic disease, such as cystic fibrosis (CF). Bryant et al. observed clusters near-identical isolates drug-resistant Mycobacterium abscessus reporting CF clinics. The similarity the suggests transmission between patients, rather than environmental acquisition. Although...
Abstract Background Missed appointments are a common occurrence in primary care the UK, yet little is known about reasons for them, or consequences of missing an appointment. This paper aims to determine missed and whether patients who miss appointment subsequently consult their general practitioner (GP). Secondary compare psychological morbidity, previous with GPs between subjects comparison group. Methods Postal questionnaire survey prospective medical notes review adult group attended...
Background The frequencies of various causes pulmonary granulomas in pathological material are unknown, as is the influence geographical location on aetiology. aim this study was to identify specimens, define their frequencies, and determine whether these vary by location. Methods 500 lung biopsies resections containing were reviewed retrospectively expert pathologists from 10 institutions seven countries. Fifty consecutive cases each assigned a diagnosis based histological features...
This study explores whether the prognosis of interstitial lung disease in rheumatoid arthritis (RA-ILD) has improved over time and assesses potential influence drug therapy a large multicentre UK network.We analysed data from 18 centres on patients meeting criteria for both RA ILD diagnosed 25-year period. Data included age, duration, outcome cause death. We compared all respiratory mortality between controls RA-ILD patients, assessing specific drugs four quartiles based year diagnosis.A...
Background Allergic rhinitis and asthma commonly coexist are both mediated by similar inflammatory mechanisms. Leukotriene antagonists may therefore be an alternative to corticosteroid therapy. Objective To compare oral montelukast with inhaled plus intranasal budesonide in patients seasonal allergic asthma. Patients methods A single‐blind double‐dummy placebo‐controlled crossover study was performed comparing once daily 10 mg 400 µg 200 12 asthma: mean (S.E.) age 34.0 years (2.7), forced...
Bronchial hyperresponsiveness (BHR) is a key feature of asthma and may be measured by direct methacholine challenge or indirect adenosine monophosphate (AMP) challenge. We performed retrospective analysis our database (n = 487) patients with the aim first, to compare AMP as screening tools, second, identify any relationships between BHR disease severity markers β2-adrenoceptor genotype. Of these subjects, 258 had challenge, 259 an 185 both. subjects having both, 140 (76%) were responsive...
To compare the antiasthmatic efficacy of inflammatory mediator blockade versus topical corticosteroid therapy in patients with seasonal allergic rhinitis (SAR) and asthma, 14 were enrolled into a single-blind, double-dummy, placebo-controlled crossover study comparing 2 wk (1) 400 μ g orally inhaled budesonide plus 200 intranasal (BUD) or (2) 10 mg oral montelukast cetirizine (ML + CZ). Before each treatment period, received 7 to d placebo washout. All treatments given once daily morning....
Background Measurement of domiciliary nasal peak inspiratory flow rate (PIFR) may have a role in the objective assessment treatment response seasonal allergic rhinitis (SAR). Objective We wished to evaluate relationship between measurement PIFR and variety symptoms associated with rhinitis. Methods Thirty‐eight nonasthmatic patients, mean age (SEM) 30 years (1.4), symptomatic SAR were evaluated placebo‐controlled, single‐blind, double‐dummy, three way parallel group study. Patients received...