A5015023127- Aortic aneurysm repair treatments
- Atrial Fibrillation Management and Outcomes
- Peripheral Artery Disease Management
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- ECG Monitoring and Analysis
- Diagnosis and Treatment of Venous Diseases
- Abdominal vascular conditions and treatments
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Wound Healing and Treatments
- Angiogenesis and VEGF in Cancer
- Infectious Aortic and Vascular Conditions
- Pressure Ulcer Prevention and Management
- Stroke Rehabilitation and Recovery
- Electrochemical Analysis and Applications
- Ion Channels and Receptors
- Vitamin D Research Studies
- Acute Ischemic Stroke Management
- Viral Infections and Immunology Research
Australian Institute of Tropical Health and Medicine
2021-2024
James Cook University
2020-2024
Townsville Hospital
2022
The University of Adelaide
2011-2021
Royal Adelaide Hospital
2012-2021
South Australian Health and Medical Research Institute
2015-2021
Flinders University
2011-2018
Australian Centre for Heart Health
2014
The University of Melbourne
2012
The Royal Melbourne Hospital
2012
The pivot is critical to rotors postulated maintain atrial fibrillation (AF). We reasoned that wavefronts circling the should broaden amplitude distribution of bipolar electrograms because directional information encoded in these signals. aimed determine whether Shannon entropy (ShEn), a measure signal distribution, could differentiate from surrounding peripheral regions and thereby assist clinical rotor mapping.Bipolar electrogram recordings were studied 4 systems: (1) computer simulations...
Both ageing and hypertension are known risk factors for atrial fibrillation (AF) although the pathophysiological contribution or interaction of individual remains poorly understood. Here we aim to delineate arrhythmogenic substrate in mature spontaneously hypertensive rats (SHR).SHR were studied at 12 15 months age (n = 8 per group) together with equal numbers age-matched normotensive Wistar-Kyoto control (WKY). Electrophysiologic study was performed on superfused isolated right left...
Background The aim of this study was to assess the relationship between serum lipoprotein (a) (Lp[a]) concentration and requirement for peripheral artery disease (PAD) operations or incidence major adverse cardiovascular events. Methods Results A total 1472 people with PAD presenting intermittent claudication (n=355), abdominal aortic aneurysm (n=989) critical limb ischemia (n=128) were prospectively recruited from 4 outpatient clinics in Australia. Lp(a) measured samples collected at...
Abdominal aortic aneurysm (AAA) is a weakening and expansion of the abdominal aorta. Currently, there no drug treatment to limit AAA growth. The glycocalyx (GC) outermost layer cell surface, mainly composed glycosaminoglycans (GAGs) proteoglycans. aim this review was identify potential relationship between GC disruption pathogenesis. A narrative relevant published research conducted. has been reported enhance vascular permeability, impair immune responses, dysregulate endothelial function,...
Background and Aims. The nacht domain, leucine-rich repeat, pyrin domain-containing protein 3 (NLRP3) inflammasome is upregulated in human abdominal aortic aneurysm (AAA), but its pathogenic role unclear. aims of this study were firstly to examine whether the was a mouse model AAA secondly test inhibitor colchicine limited growth. Methods. induced eight-week-old male C57BL6/J mice with topical application elastase infrarenal aorta oral 3-aminopropionitrile (E-BAPN). For aim one, activation,...
Hypertrophic cardiomyopathy (HCM) is an inherited cardiac disorder affecting one in 500 of the general population. Atrial fibrillation (AF) most common arrhythmia patients with HCM. We sought to characterize atrial electrophysiological and structural substrate young aging Gly203Ser troponin-I transgenic mice. At 30 weeks 50 age (n = 6 per strain each group), left atrium was excised placed on a multi-electrode array (MEA) for study; subsequent histological analyses plasma samples were...