Mellanie Fontes‐Dutra

ORCID: 0000-0003-0334-0740
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About
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Research Areas
  • Autism Spectrum Disorder Research
  • Genetics and Neurodevelopmental Disorders
  • Adenosine and Purinergic Signaling
  • Neuroscience and Neuropharmacology Research
  • Functional Brain Connectivity Studies
  • MicroRNA in disease regulation
  • Data Visualization and Analytics
  • Communication and COVID-19 Impact
  • RNA Interference and Gene Delivery
  • Herpesvirus Infections and Treatments
  • Neuroendocrine regulation and behavior
  • Poxvirus research and outbreaks
  • Nerve injury and regeneration
  • Child Development and Digital Technology
  • Education during COVID-19 pandemic
  • Data-Driven Disease Surveillance
  • Neuroscience and Neural Engineering
  • RNA regulation and disease
  • Reproductive System and Pregnancy
  • Signaling Pathways in Disease
  • Plant Virus Research Studies
  • COVID-19 and healthcare impacts
  • Science and Science Education
  • Healthcare Regulation
  • Adolescent and Pediatric Healthcare

Universidade do Vale do Rio dos Sinos
2022-2024

Universidade Federal do Rio Grande do Sul
2014-2023

Fundação Oswaldo Cruz
2018-2022

University of Central Lancashire
2021

Autism Research Institute
2021

Universidade Federal do Rio Grande
2018

Autism spectrum disorder (ASD) is characterized by impairments in both social communication and interaction repetitive or stereotyped behaviors. Although its etiology remains unknown, genetic environmental risk factors have been associated with this disorder, including the exposure to valproic acid (VPA) during pregnancy. Resveratrol (RSV) an anti-inflammatory antioxidant molecule known prevent VPA animal model of autism. This study aimed analyze effects prenatal VPA, as well possible...

10.3389/fnsyn.2018.00009 article EN cc-by Frontiers in Synaptic Neuroscience 2018-05-22

Autism spectrum disorder can present a plethora of clinical conditions associated with the disorder, such as greater brain volume in first years life significant percentage patients. We aimed to evaluate water content, blood-brain barrier permeability, and expression aquaporin 1 4, GFAP valproic acid-animal model, assessing effect resveratrol. On postnatal day 30, Wistar rats acid group showed permeability Evans blue dye higher proportion volume, prevented both by Prenatal exposition...

10.1002/jdn.10137 article EN International Journal of Developmental Neuroscience 2021-07-02

Autism spectrum disorder (ASD) is a prevalent neurodevelopmental characterized by several alterations, including disorganized brain cytoarchitecture and excitatory/inhibitory (E/I) imbalance. We aimed to analyze aspects associated with the inhibitory components in ASD, using bioinformatics develop notions about embryonic life tissue analysis for postnatal life. analyzed microarray RNAseq datasets of embryos from different ASD models, demonstrating that regions involved neuronal development...

10.3390/ijms23084075 article EN International Journal of Molecular Sciences 2022-04-07

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by social interaction deficits and repetitive/stereotyped behaviors. Its prevalence increasing, affecting one in 36 children the United States. The valproic acid (VPA) induced animal model of ASD reliable method for investigating cellular, molecular, behavioral aspects related to disorder. Trans-Resveratrol (RSV), polyphenol with anti-inflammatory antioxidant effects studied various diseases, has recently...

10.1016/j.ibneur.2023.09.008 article EN cc-by-nc-nd IBRO Neuroscience Reports 2023-09-23

Objetivo: Analisar e descrever através de uma revisão sobre quais são os possíveis impactos, metodologias prevenção soluções dentro dos parâmetros pandêmicos da Covid-19, maneira clara destinada ao público, com intuito promover conscientização ampliar o conhecimento. Revisão bibliográfica: A pesquisa foi realizada forma exploratória qualitativa no contexto acontecimentos atuais, nas opiniões científicas encontradas na atualidade dados epidemiológicos do COVID-19. Demonstrou-se aumento nocivo...

10.25248/reas.e3837.2020 article PT Revista Eletrônica Acervo Saúde 2020-08-06

ABSTRACT Objectives We aimed to calculate the weekly growth of incidence and effective reproductive number (Rt) 2022 Monkeypox epidemic during its introduction in Brazil. Methods described case distribution country calculated trend Rt four geographical states with highest reports. By using two regression approaches, count model Prais-Winsten, we relative increase. Moreover, estimated for period between 24th 50th days after first official report, a serial interval reported another population...

10.1101/2022.08.16.22278806 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2022-08-17

ABSTRACT Objective: Describe the development, implementation, and utilization of dashboards for epidemiological analysis through open data research during COVID-19 pandemic. Methods: The were designed to analyze related public from various sources, including official government social media, at world level. Data processing cleaning techniques used join datasets. We calculated Spearman correlation coefficient between COVID-like symptoms University Maryland Facebook Health research, called...

10.1590/1980-549720240004 article EN cc-by Revista Brasileira de Epidemiologia 2024-01-01

Autism spectrum disorder (ASD) is characterized by impaired social communication and interaction associated with repetitive or stereotyped behaviour. Prenatal valproic acid (VPA) exposure in rodents a commonly used model of ASD. Resveratrol (RSV) has been shown to prevent interneuronal behavioural impairments the VPA model. We investigated effects prenatal RSV on GABAergic synaptic transmission, brain oscillations genic expression interneuron-associated transcription factor LHX6 primary...

10.1111/ejn.15893 article EN European Journal of Neuroscience 2022-12-12

This article contains data of Social Transmission Food Preference in an animal model autism and the evaluation a set microRNA analyzed autistic patients autism. The analyses absolute consumption two flavored food by male rats prenatally exposed to valproic acid (VPA) treated with resveratrol (RSV), showed that VPA animals show trend eat less presented demonstrator rat. We also identified 13 similar levels among rodents' experimental groups, as well 11 no alterations between control subjects....

10.1016/j.dib.2018.04.047 article EN cc-by Data in Brief 2018-04-21

RESUMO Objetivo: Descrever o desenvolvimento, a implementação e uso de painéis para análise epidemiológica dados abertos durante pandemia COVID-19. Métodos: Os foram criados analisar públicos relacionados á COVID-19 várias fontes, incluindo oficiais dos governos redes sociais, nível global. Técnicas processamento limpeza utilizadas aglutinar os bancos dados. Calculamos coeficiente correlação Spearman entre as curvas sintomas gripais da pesquisa Universidade Maryland em conjunto com Facebook,...

10.1590/1980-549720240004.2 article PT cc-by Revista Brasileira de Epidemiologia 2024-01-01

O Grupo de Trabalho 2, no II Encontro Brasileiro Divulgadores Ciência em 2023, discutiu a organização e estruturação campanhas temáticas científicas sociais redes sociais. A partir experiências anteriores, foram abordados tópicos desde idealização teórica interdisciplinar, até datas, palavras-chave, hashtags participação coletivos personalidades, dentro uma mesma identidade visual linguagem das propostas. Como finalização do grupo trabalho, organizou-se proposta campanha, com vídeos...

10.18264/repdcec.v3i3.249 article PT cc-by Revista Educação Pública 2024-11-15

The present research aimed to perform data survey and analysis of children teenagers among 0- 19-year-olds related SARS (severe acute respiratory syndrome) COVID-19 in populations with or without disabilities during the year 2020. database used for evaluations was Sivep-Gripe, made available by Ministry Health. did not variables regarding type disability a proxy created binary variable Down syndrome qualitative clinical descriptive morbidity. This limitation hindered consideration experience...

10.18061/dsq.v41i3.8417 article EN cc-by-nc-nd Disability Studies Quarterly 2021-09-13
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