A5037574143- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Astro and Planetary Science
- Stellar, planetary, and galactic studies
- Astrophysics and Star Formation Studies
- Astronomy and Astrophysical Research
- MicroRNA in disease regulation
- Astronomical Observations and Instrumentation
- RNA Research and Splicing
- Planetary Science and Exploration
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Computational Drug Discovery Methods
- Geophysics and Gravity Measurements
- Cancer Immunotherapy and Biomarkers
- Reproductive biology and impacts on aquatic species
- Sperm and Testicular Function
- Astrophysical Phenomena and Observations
- Economic and Financial Impacts of Cancer
- SARS-CoV-2 and COVID-19 Research
- High-pressure geophysics and materials
- Vitamin C and Antioxidants Research
- Health Systems, Economic Evaluations, Quality of Life
- Genomics and Phylogenetic Studies
- Circular RNAs in diseases
- Space Exploration and Technology
Physical Research Laboratory
2021-2023
Indian Institute of Technology Gandhinagar
2023
Central University of Punjab
2016-2022
Jaypee University of Information Technology
2015
University of Rajasthan
2009
Lung cancer is the leading cause of cancer‐related deaths worldwide. Recent advances in whole genome transcriptome analysis have enabled identification numerous members a novel class non‐coding RNAs, i.e., long RNAs (lncRNAs), which play important roles wide range biological processes and whose deregulation causes human disease, including cancer. Herein we provide comprehensive survey lncRNAs associated with lung cancer, particular focus on functions that either facilitate or inhibit...
Abstract Despite the availability of various diagnostic procedures, a tissue biopsy is still indispensable for routine diagnosis lung cancer. However, inaccurate diagnoses can occur, leading to inefficient cancer management. In this context, use circulating micro RNA s (mi s) may serve as tools liquid biopsies, and biomarkers better understand molecular mechanisms involved in progression We identified miR‐590‐5p potential prognostic marker non‐small cell ( NSCLC ). were able detect mi blood...
Dysregulated expression profiles of microRNAs (miRNAs) have been observed in several types cancer, including non-small cell lung cancer (NSCLC); however, the diagnostic and prognostic potential circulating miRNAs NSCLC remains largely undefined. Here we found that miR-320a was significantly down-regulated (~5.87-fold; p < 0.0001) patients ( n = 80) compared to matched control plasma samples from healthy subjects 80). Kaplan-Meier survival analysis revealed with lower levels had...
We present the discovery and characterization of a sub-Saturn exoplanet, TOI-6038~A~b, using PARAS-2 spectrograph. The planet orbits bright ($m_V=9.9$), metal-rich late F-type star, TOI-6038~A, with $T_{\rm{eff}}=6110\pm100~\mathrm{K}$, $\log{g}=4.118^{+0.015}_{-0.025}$, $[{\rm{Fe/H}}]=0.124^{+0.079}_{-0.077}$ dex. system also contains wide-orbit binary companion, TOI-6038~B, an early K-type star at projected separation $\approx3217$ AU. combined radial velocity data from photometric...
Abstract We present the discovery and characterization of a sub-Saturn exoplanet, TOI-6038 A b, using PARAS-2 spectrograph. The planet orbits bright ( m V = 9.9), metal-rich late F-type star, A, with T eff 6110 ± 100 K, <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" overflow="scroll"> <mml:mi>log</mml:mi> <mml:mi>g</mml:mi> <mml:mo>=</mml:mo> <mml:mn>4.11</mml:mn> <mml:msubsup> <mml:mrow> <mml:mn>8</mml:mn> </mml:mrow> <mml:mo>−</mml:mo> <mml:mn>0.025</mml:mn> <mml:mo>+</mml:mo>...
Despite the availability of advanced technology to detect and treat esophageal squamous cell carcinoma (ESCC), 5-year survival rate ESCC patients is still meager. Recently, long non-coding RNAs (lncRNAs) have emerged as essential players in diagnosis prognosis various cancers.This pilot study focused on identifying circulating lncRNAs liquid biopsy markers for ESCC.We performed next-generation sequencing (NGS) profile healthy individuals' blood samples. The expression top five upregulated...
The functional success of the reversal vas occlusion by styrene maleic anhydride (RISUG), using solvent vehicle, Dimethyl Sulphoxide (DMSO), has been investigated. Reversal with DMSO was carried out in Wistar albino rats 90 days after bilateral occlusion. body weight, organ sperm characteristics, fertility test and teratology, including skeletal morphology were evaluated animals F(1) progenies to assess reversal. Body weight cauda epididymal characteristics comparable control. Ejaculated...
We report the discovery and characterization of a transiting sub-Saturn exoplanet TOI-6651b using PARAS-2 spectroscopic observations. The host, TOI-6651 ($m_{V}\approx 10.2$), is sub-giant, metal-rich G-type star with $[{\rm Fe/H}] = 0.225^{+0.044}_{-0.045}$, $T_{\rm eff} 5940\pm110\ \mathrm{K}$, $\log{g} 4.087^{+0.035}_{-0.032}$. Joint fitting radial velocities from spectrograph transit photometric data Transiting Exoplanet Survey Satellite (TESS) reveals planetary mass $61.0^{+7.6}_{-7.9}\...
We present the discovery of a transiting massive giant planet around TOI-4603, sub-giant F-type star from NASA’s Transiting Exoplanet Survey Satellite (TESS). The newly discovered has radius 1.042 −0.035 +0.038 R J and an orbital period 7.24599 −0.00021 +0.00022 days. Using radial velocity measurements with PARAS TRES spectrographs, we determined planet’s mass to be 12.89 −0.57 +0.58 M , resulting in bulk density 14.1 −1.6 +1.7 g cm −3 . This makes it one few known planets extreme density....
We report here the discovery of a hot Jupiter at an orbital period $3.208666\pm0.000016$ days around TOI-1789 (TYC 1962-00303-1, $TESS_{mag}$ = 9.1) based on TESS photometry, ground-based and high-precision radial velocity observations. The observations were obtained from high-resolution spectrographs, PARAS Physical Research Laboratory (PRL), India, TCES Th\"uringer Landessternwarte Tautenburg (TLS), Germany, transit using 0.43~m telescope PRL with Bessel-$R$ filter. host star is slightly...
We present the discovery of a transiting massive giant planet around TOI-4603, sub-giant F-type star from NASA's Transiting Exoplanet Survey Satellite (TESS). The newly discovered has radius $1.042^{+0.038}_{-0.035}$ $R_{J}$, and an orbital period $7.24599^{+0.00022}_{-0.00021}$ days. Using radial velocity measurements with PARAS {and TRES} spectrographs, we determined planet's mass to be $12.89^{+0.58}_{-0.57}$ $M_{J}$, resulting in bulk density $14.1^{+1.7}_{-1.6}$ g ${cm^{-3}}$. This...