A5007084651- Drug Solubulity and Delivery Systems
- Food composition and properties
- Crystallization and Solubility Studies
- Polysaccharides Composition and Applications
- Analytical Methods in Pharmaceuticals
- Pharmaceutical studies and practices
- Protein purification and stability
- Food Chemistry and Fat Analysis
- Microencapsulation and Drying Processes
- Meat and Animal Product Quality
- Nanocomposite Films for Food Packaging
- Proteins in Food Systems
- Granular flow and fluidized beds
- Advanced Drug Delivery Systems
- Microwave-Assisted Synthesis and Applications
- Mineral Processing and Grinding
- Clinical Nutrition and Gastroenterology
- Thermal and Kinetic Analysis
- Spectroscopy and Chemometric Analyses
- Microbial Metabolites in Food Biotechnology
- Freezing and Crystallization Processes
- Bone Tissue Engineering Materials
- Quality and Safety in Healthcare
- Safe Handling of Antineoplastic Drugs
Roche (Switzerland)
2017-2021
Martin Luther University Halle-Wittenberg
2009-2014
University of Szeged
2005-2007
Drug load plays an important role in the development of solid dosage forms, since it can significantly influence both processability and final product properties. The percolation threshold active pharmaceutical ingredient (API) corresponds to a critical concentration, above which abrupt change drug characteristics occur. objective this study was identify poorly water-soluble with regard dissolution behavior from immediate release tablets. API particle size on also studied. Formulations...
Abstract The freeze‐casting technique was used to formulate porous solid bodies containing theophylline as an active pharmaceutical ingredient, potato starch a filler and citric acid or saccharose binding agents. Aqueous suspensions of the ingredients were frozen at three different temperatures. aim this work investigate influence freezing temperature on ice crystal growth rate resulting porosity freeze‐casted samples. impact solidification analyzed via contact angle measurements. expressed...
Abstract The metastable zone width (MZW) of a multi‐component system as influenced by the process parameters cooling rate, agitation speed, and additive concentration was determined via ultrasound velocity measurements. results were compared with those obtained optical back‐reflectance measurements (ORM) using coconut oil model substance. Increasing rate led to shift nucleation point lower temperatures. This tendency better visualized ultrasonic curves while significant disturbance ORM...
The aim of this study was to investigate the effects microwave irradiation and storage on moisture content, adsorption behavior swelling properties potato (B-type) maize starches (A-type). Volumetric heating resulted in reversible loss from both types samples. crystallinity starch decreased, whereas its water retention capacity power were increased irreversibly, reversibly by thermal process applied. corresponding parameters not influenced significantly dielectric heating; may be related...
The aim of this work is to analyze the particle characteristics, such as shape, roundness and size, starches extracted from Florencia waxy maize hybrids. micromeritics structural properties samples were examined. evaluation flow properties, densification compression behaviour powders was carried out. Physical parameters swelling characteristics tablets containing starch also studied. Starch compared with respect their applicability excipients in tablet formulation. exhibited identical...
Abstract Product design is an active area of research. In a top‐down approach to product design, the required properties dictate development from very basic choice functional material use for defined task up processing render in suitable form. This article focuses on crystalline solids with particular field application mind and shows how process conditions can be used both generate tailor these properties. The examples selected are biased towards novel pharmaceutical applications; principles...