A5040389646- Ocular Surface and Contact Lens
- COVID-19 Clinical Research Studies
- Glaucoma and retinal disorders
- Long-Term Effects of COVID-19
- Dermatology and Skin Diseases
- SARS-CoV-2 and COVID-19 Research
- Obstructive Sleep Apnea Research
- Intensive Care Unit Cognitive Disorders
- Advancements in Transdermal Drug Delivery
- Respiratory Support and Mechanisms
- Allergic Rhinitis and Sensitization
- Healthcare and Venom Research
- Venous Thromboembolism Diagnosis and Management
- Urticaria and Related Conditions
- Neuroendocrine Tumor Research Advances
- Heparin-Induced Thrombocytopenia and Thrombosis
- Nasolacrimal Duct Obstruction Treatments
- Corneal surgery and disorders
- Facial Rejuvenation and Surgery Techniques
- Cardiovascular Syncope and Autonomic Disorders
- Ocular Infections and Treatments
- Cutaneous Melanoma Detection and Management
- Diabetes Treatment and Management
- Retinal Diseases and Treatments
- Kawasaki Disease and Coronary Complications
Aintree University Hospitals NHS Foundation Trust
2022
University of Liverpool
2022
Hinchingbrooke Hospital
2018-2021
Public Health Scotland
2021
Oxford University Clinical Research Unit
2021
Eijkman Institute for Molecular Biology
2021
Oxford University Clinical Research Unit Indonesia
2021
Nepal Health Research Council
2021
NIHR Clinical Research Network
2021
National Institute for Health Research
2021
Purpose to determine whether primary trabeculectomy or medical treatment produces better outcomes in term of quality life (QoL), clinical effectiveness and safety patients presenting with advanced glaucoma. Design multicentre randomised controlled trial Participants between June 3, 2014 May 31, 2017, 453 adults newly diagnosed open angle glaucoma at least one eye (Hodapp Classification) were recruited from 27 secondary care departments the UK, 227 allocated 226 management. Methods...
Précis: In this study, we found a high prevalence of obstructive sleep apnea (OSA) among patients with primary open-angle glaucoma (POAG) but was not different (nor OSA more severe) to matched people without glaucoma. Rationale: It has been proposed that might be contributing factor in the development POAG and by extension there could role for screening OSA. Objectives: To assess whether is from examine associations between apnea-hypopnea index (AHI) markers functional structural changes...
To study the contribution of each eye to reflex tear response, after unilateral and bilateral topical anesthesia.A closed-eye, modified Schirmer test was performed bilaterally in 8 normal subjects, a controlled environment chamber set 23°C, 45% relative humidity, 0.08 m/s airflow. Eye drops were instilled into 10 minutes before test. Experiments as follows: 1) saline (control), 2) anesthesia (ipsilateral anesthetic; contralateral saline), 3) anesthesia.There no difference between-eye wetting...
Purpose Holly et al. (1984) showed that the wetting length of Schirmer strip is influenced by evaporation and may be affected ambient humidity. This could explain poor reproducibility in different environmental conditions. We therefore studied how preventing conditions relative Methods A closed-eye test was performed bilaterally 8 subjects with normal eyes (3 male; mean age 35.5 years SD ± 25), a Weiss-Gallenkamp controlled chamber, at temperature 23°C laminar airflow 0.08 m/s. Tests were...
Purpose Tear osmolarity (tOsm) is used as a measure of severity in dry eye disease (DED) and has also been proposed an index body hydration. Currently DED the level tear hyperosmolarity compared with that normal population. We propose more valid reference point for both hydration could be acquired by measuring tOsm after period evaporative suppression. Methods Eight (N) eight subjects were recruited their measured TearLab® osmometer uncontrolled environmental conditions. They then entered...
<b>Rationale:</b> Obstructive sleep apnea (OSA) has been implicated in the pathophysiology of primary open-angle glaucoma (POAG) but its prevalence this population is unknown. <b>Objectives:</b> To assess whether OSA among patients with POAG different than people without and to examine potential associations between hypopnea index (AHI) markers functional structural deficits POAG. <b>Methods:</b> Unselected control subjects were consecutively recruited a single center. A comprehensive ocular...