A5101572929- Child Abuse and Trauma
- Intimate Partner and Family Violence
- Homicide, Infanticide, and Child Abuse
- Schizophrenia research and treatment
- Genetic Neurodegenerative Diseases
- Genetics and Neurodevelopmental Disorders
- Functional Brain Connectivity Studies
- Mitochondrial Function and Pathology
- Neurological disorders and treatments
- Chemical Reactions and Isotopes
- Migration, Health and Trauma
- Homelessness and Social Issues
- Child Welfare and Adoption
- Neurotransmitter Receptor Influence on Behavior
- Advanced Neuroimaging Techniques and Applications
- Down syndrome and intellectual disability research
- Attention Deficit Hyperactivity Disorder
- PARP inhibition in cancer therapy
- Steroid Chemistry and Biochemistry
- Children's Rights and Participation
- Genomics and Rare Diseases
- CCD and CMOS Imaging Sensors
- Drug Transport and Resistance Mechanisms
- Genomic variations and chromosomal abnormalities
- Genetic Associations and Epidemiology
Government of Victoria
2019-2023
The University of Melbourne
2012-2020
Department of Health and Human Services
2019
Imperial College London
2009-2016
Hammersmith Hospital
2009
University College London
1995-1997
Ethics applications to conduct research with children who have experienced domestic violence will frequently raise a red flag ethics committees about the potential for risk and re-traumatization. On other hand, such sensitive can enable hidden, marginalized population their voices heard. It deliver findings children’s lives that inform otherwise adult-centric research, policy practice initiatives. The authors highlight ethical concerns practical solutions using examples from violence, family...
An increase in the severity of schizophrenia through consecutive generations (anticipation) has been found some studies families with affected members. Anticipation five neurologlcai disorders is known to arise from expansion CAG repeats between individuais. The 'repeat detection' method was used screen indlviduai genomes for size such expansions a sampie schizophrenic and normai sub jects. Comparison frequency distribution observed patients that normal subjects, showed there are...
Children who live in households where domestic violence is occurring have been variously described the literature over time as silent witnesses, a cohort “exposed” to violence, and more recently, individual victim survivors active agents their own right, each with lived experience of violence. Research methodologies this arena shifted from adult-focused measurements impacts on children qualitative attempts understand child’s perspective. In doing so, there notions giving “voice voiceless” no...
Previous microarray analysis of gene expression in frontal cortex showed differential genes associated with synaptic function schizophrenia compared to matched-controls two independent cohorts. One these validated both cohorts, SLC30A3, which encodes the Zinc Transporter 3 (ZNT3), is localised vesicles glutamate synapses and known be involved cognitive function. In view robust depletion SLC30A3 mRNA studies importance this function, we investigated whether single nucleotide polymorphism...
Introduction Intimate partner violence detrimentally affects the social and emotional well-being of children mothers. These two populations are impacted both individually within context their relationship with one another. Child mental health, maternal health mother–child may be impaired as a consequence. Early intervention to prevent or arrest attachment child development is needed. Dyadic relational interventions that include mothers children, such child–parent psychotherapy, effective in...
The involvement of genes with expanded tracts (CAG)n in some neurodegenerative diseases is well established. Whether containing these motifs could also have a role degenerative affecting the retina, which neural origin, unknown. We investigated expansions as cause disease panel eight autosomal dominant retinitis pigmentosa (ADRP) pedigrees, including families known to map RP9, RP11, and RP13 loci, using technique "repeat expansion detection" (RED). An was detected one unlinked families, but...