A5010085276- Organoselenium and organotellurium chemistry
- Chemical Synthesis and Reactions
- Organic Chemistry Cycloaddition Reactions
- Molecular Sensors and Ion Detection
- Sulfur-Based Synthesis Techniques
- Asymmetric Synthesis and Catalysis
- Sulfur Compounds in Biology
- Selenium in Biological Systems
- Luminescence and Fluorescent Materials
- Synthetic Organic Chemistry Methods
- Nanocluster Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Enzyme Catalysis and Immobilization
- Insect and Pesticide Research
- Free Radicals and Antioxidants
- Gold and Silver Nanoparticles Synthesis and Applications
- Organometallic Compounds Synthesis and Characterization
- Advanced Nanomaterials in Catalysis
- Vanadium and Halogenation Chemistry
- Synthesis of heterocyclic compounds
- Crystal structures of chemical compounds
- Crystallization and Solubility Studies
- Coordination Chemistry and Organometallics
- X-ray Diffraction in Crystallography
- Catalytic C–H Functionalization Methods
Universidade de São Paulo
2014-2024
Hospital Universitário da Universidade de São Paulo
2024
Instituto Butantan
2013-2023
Universidade de Vigo
2017
Universidade Cidade de São Paulo
2016
Universidade Federal de São Carlos
2006-2013
Rede de Química e Tecnologia
2013
Universität Hamburg
2003-2006
Universidade Federal do Paraná
1997-2004
Vilnius University
2004
A new chemosensor based on Seleno-BODIPY (4) was designed and synthesized for the rapid sensitive detection of CN–, F−, OH– ions in THF, exhibiting ultra-low limits 26.26 nM, 43.05 8.64 respectively, through a turn-on fluorescent process. The seleno-funcionalization step novel methodology developed by our group, allowing direct functionalization BODIPY core. This procedure involves quick reaction utilizing Ph2Se2 as selenium source, BPO (benzoyl peroxide), p-TSA (p-toluenesulfonic acid)...
A series of optically active helical copolymers phenylacetylenes are prepared by the rhodium‐catalyzed copolymerization imidazolidinone‐linked, catalytically achiral and inactive chiral phenylacetylenes. The obtained chiral/achiral exhibit an induced circular dichroism in UV–vis regions copolymer backbones resulting from a preferred‐handed conformation biased imidazolidinone units incorporated copolymers. found to catalyze asymmetric Diels–Alder reaction produce products with moderate...
Selenium uptake and its content in soybean grains are affected by Se application methods. This study evaluated the impact of foliar combined with a multi-nutrient fertilizer (MNF) on soybean, establishing threshold to better understand relationship between yield two genotypes (58I60 Lança M5917). Two trials were conducted 4 × 2 factorial design: four rates (0, 10, 40, 80 g ha-1) methods (Se or not MNF). Foliar fertilizers applied twice, at phenological stages beginning pod development grain...
We describe a recyclable heterogeneous palladium nanocatalyst for the selective hydrogenation of alkynes to alkenes. The catalyst was prepared through decomposition organometallic precursor Pd2(dba)3 over magnetic support, obtaining well-dispersed Pd nanoparticles that formed exclusively on support surface, with average diameter 3.5 ± 0.8 nm. catalytic activity investigated in reactions alkenes and alkynes, chemo- stereoselectivity were evaluated benzyl-propargylamines. is highly performing...
Hypervalent tellurium compounds (telluranes) are promising therapeutical agents with negligible toxicities for some diseases in animal models. The C-Te bond of organotellurium is commonly considered unstable, disfavoring their applicability biological studies. In this study, the stability a set telluranes composed an inorganic derivative and noncharged charged organic derivatives was monitored aqueous media 1H, 13C, 125Te NMR spectroscopy high-resolution mass spectrometry. Organic were found...
ABSTRACT Invasive Candida albicans infections are a serious health threat for immunocompromised individuals. Fluconazole is most commonly used to treat these infections, but resistance due the overexpression of multidrug efflux pumps grave concern. This study evaluated ability five synthetic organotellurium compounds reverse fluconazole C. clinical isolates. Compounds 1 4, at <10 μg/ml, ameliorated Saccharomyces cerevisiae strains overexpressing major Cdr1p and Mdr1p, whereas compound 5...
Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system (CNS). The persistent inflammation being mainly attributed to local oxidative stress inflammasome activation implicated in ensuing demyelination axonal damage. Since new control measures remain necessary, we evaluated preventive therapeutic potential a beta-selenium-lactic acid derivative (LAD-βSe), which source organic selenium under development, experimental autoimmune encephalomyelitis (EAE)...
The compounds utilized by the soybean stink bug Piezodorus guildinii as alarm pheromone were characterized analysis of chemical composition metathoracic scent gland secretions from adult bugs. In addition to characteristic hydrocarbons, (E)-2-hexenal and (E)-4-oxo-2-hexenal detected major constituents. These previously described in several other pentatomid species.
N-methyl-2-pyrrolidonium methyl sulfonate, a Brønsted acid ionic liquid, promoted the transesterification of soybean oil with ethanol giving high quality fatty ethyl ester. At end reaction, after distillation excess ethanol, spontaneous phase separation took place. While clear upper corresponded to ester, lower was composed mixture glycerol byproduct and catalyst. By addition stoichiometric amount appropriated reagents resulting mixture, new liquid-catalyzed process allows conversion into...
Resistance to fluconazole, a commonly used azole antifungal, is challenge for the treatment of fungal infections. can be mediated by overexpression ABC transporters, which promote drug efflux that requires ATP hydrolysis. The Pdr5p transporter Saccharomyces cerevisiae well-known model study this mechanism antifungal resistance. present investigated effects 13 synthetic compounds on Pdr5p.Among tested compounds, four contained tellurium-butane group and shared structural similarities were...
An efficient, green and solvent-free catalysed Prins-cyclization reaction based on the simple grinding of an aldehyde a homoallylic alcohol in presence catalytic amount p-TSA silica gel is reported. By this protocol were synthesized tetrahydropyran odorants including commercial Florol® Clarycet®, one two steps respectively.
Two new bio-inspired fluorescein derivatives were successfully synthesized and both the compounds showed a “turn on” fluorescence in presence of trivalent (Al<sup>3+</sup>, Fe<sup>3+</sup>, Ga<sup>3+</sup>, Cr<sup>3+</sup>) Hg<sup>2+</sup>metal ions, forming mononuclear complexes acetonitrile.