- Reproductive Biology and Fertility
- Effects of Environmental Stressors on Livestock
- Genomics, phytochemicals, and oxidative stress
- Sperm and Testicular Function
- Bee Products Chemical Analysis
- Effects and risks of endocrine disrupting chemicals
- Ruminant Nutrition and Digestive Physiology
- Coccidia and coccidiosis research
- Energy and Environment Impacts
- Osteoarthritis Treatment and Mechanisms
- Astro and Planetary Science
- Meat and Animal Product Quality
- Proteoglycans and glycosaminoglycans research
- Advanced Glycation End Products research
- Reproductive Physiology in Livestock
- Total Knee Arthroplasty Outcomes
- Space Exploration and Technology
- Orthopaedic implants and arthroplasty
- Advanced Chemical Sensor Technologies
- Endoplasmic Reticulum Stress and Disease
- Selenium in Biological Systems
- Inflammatory mediators and NSAID effects
- Planetary Science and Exploration
- Orthopedic Infections and Treatments
- Animal Nutrition and Physiology
Hiroshima University
2021-2022
Oncolys BioPharma (Japan)
2019-2021
Nihon University
2011
Abstract Histological and molecular changes were examined to investigate the effects of long‐term administration glucosamine (GlcN) chondroitin sulfate (CS) in a model spontaneous osteoarthritis (OA) Hartley guinea pigs. Three groups female 3‐week‐old pigs received GlcN, CS, neither agent, respectively. Five animals each group sacrificed at 8, 12, 18 months age. At 8 age, had severe degeneration knee joint cartilage, chondrocyte apoptosis, marked reduction tissue total RNA, decreases...
We compared the results of 1-stage uncemented bilateral total hip arthroplasty (THA) performed in 49 patients (98 hips) with those 2-stage THA during same hospital stay 40 (80 hips). There was no significant difference mean Harris Hip Score preoperatively and at final follow-up between 2 groups. Radiographic evaluation group revealed acetabular component stable 95 hips possibly unstable 3. The femoral bone-ingrown 91 fibrous 7. In group, 77 71 9. both groups, exhibited clear signs loosening,...
Objective: Cells have increased susceptibility to activation of apoptosis when suffering heat stress (HS). An effective supplementation strategy mimic heat-induced bovine mammary epithelial cells (MECs) is necessary maintain optimal milk production. This study aimed investigate possible protective effects the anti-apoptotic activity 5-aminolevulinic acid (5-ALA) against HS-induced damage MECs.Methods: Bovine MECs were pretreated with or without 5-ALA at concentrations 10, 100, and 500 μM for...
The conservation of mammary gland physiology by maintaining the maximum number epithelial cells (MECs) is utmost importance for optimum amount milk production. In a state negative energy balance, palmitic acid (PA) reduces bovine MECs. However, there no effective strategy against PA-induced apoptosis present study, 5-aminolevulinic (5-ALA) was established as remedial agent MAC-T (an line MECs). PA-treated cells, apoptosis-related genes BCL2 and BAX were down- upregulated, respectively....
High summer temperatures have deleterious effects on oocyte developmental competence. The antioxidant and autophagy-related properties of 5-aminolevulinic acid (5-ALA) gives the compound a broad range biological activities. This study aimed to evaluate of: 1) high temperature-humidity index (THI) competence bovine oocytes, 2) 5-ALA administration in combination with sodium ferrous citrate (SFC) during vitro maturation (IVM) evaluated at THI. Bovine ovaries were collected from local...
食肉の比熱は,水分,脂肪およびそれ以外の成分に影響される.示差走査熱量計を用いて,ゼラチン,寒天,脂肪酸および食肉(牛肉,豚肉,鶏肉)の比熱を0~100°Cの温度範囲で測定した.水分の影響をみると,酸化アルミナでCP=0.04x+0.50(Cp:30°Cでの比熱,X:水分%)の関係があった.ゼラチンと寒天を用いて比較すると,乾燥品の比熱(10~100°Cの範囲の平均値)はそれぞれ1.49,1.37kJ/kg•Kであり,水分92%を加えるとそれぞれ3.53,3.46 kJ/kg•Kとなり,ほぼ同程度の影響が確認された.ウシ,ブタ,ニワトリの脂肪の主成分であるC16:0, C18:0, C18:1,...
This study investigated the effects of 5-aminolevulinic acid (5-ALA) on motility parameters, mitochondrial membrane depolarization, and ATP levels in chicken sperm.The pooled semen from Barred Plymouth Rock males was used. In first experiment, diluted 4-times with phosphate-buffered saline (PBS (-)) containing various concentrations (0, 0.01, 0.05, 0.1 mM) 5-ALA, then sperm parameters after incubation were evaluated by computer-assisted analysis (CASA). second PBS (-) 0.05 mM depolarization...
The present study aimed to evaluate the effects of 5-aminolevulinic acid (5-ALA) on Eimeria tenella infection in laying hens. Oocyst shedding and histopathology were evaluated. A reduced oocyst was observed 5 7 days post-infection (dpi) 5-ALA-administered group, but total number oocysts during first period not different between control 5-ALA-treated groups. After E. attack infection, group lasted less long than that controls. During period, fecal significantly lower group. However, parasite...