A5043125372- Electrospun Nanofibers in Biomedical Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Nanoparticle-Based Drug Delivery
- Silk-based biomaterials and applications
- Advanced Drug Delivery Systems
- RNA Interference and Gene Delivery
- Bone Tissue Engineering Materials
- Tissue Engineering and Regenerative Medicine
- Graphene and Nanomaterials Applications
- Wound Healing and Treatments
- Antimicrobial agents and applications
- biodegradable polymer synthesis and properties
- Nanoplatforms for cancer theranostics
- Endodontics and Root Canal Treatments
- Dental materials and restorations
- 3D Printing in Biomedical Research
- Microfluidic and Capillary Electrophoresis Applications
- Periodontal Regeneration and Treatments
- Advancements in Transdermal Drug Delivery
- Analytical Chemistry and Chromatography
- Ureteral procedures and complications
- Pickering emulsions and particle stabilization
- Analytical chemistry methods development
- Infectious Aortic and Vascular Conditions
- Advanced biosensing and bioanalysis techniques
Hacettepe University
2015-2024
GTx (United States)
2017
Office of Basic Energy Sciences
2016
Middle East Technical University
1992-2001
Gelatin is a natural polymer used in pharmaceutical and medical applications, especially the production of biocompatible biodegradable wound dressings drug delivery systems. granules hydrate, swell solubilize water, rapidly degrade vivo. The durability these materials could, however, be prolonged by cross-linking aldehydes, carbodiimides, aldose sugars, but biocompatibility collagenous biomaterials profoundly influenced nature extent cross-linking. In this study, gelatin sponges were...
The objective of this study was to develop polysorbate 80 coated and Atorvastatin loaded poly(lactic-co-glycolic acid)-block-poly(ethylene glycol) (PLGA-b-PEG) nanoparticles investigate advantages coating on for brain delivery Atorvastatin. were prepared by nanoprecipitation method. effects polymer concentration, PEG content the particle size, drug loading efficiency release behaviour investigated. Additionally, cellular uptake targeting formulated studied. Particle sizes in range 30–172 nm...
Abstract Aim To investigate the effect of several chelating solutions on transforming growth factor ( TGF ‐β) release from dentine discs and their subsequent impact cellular behaviour. Methodology Human were prepared with a standardized diameter disinfected using 1.5% Na OC l for 5 min. The then exposed to 17% ethylenediaminetetraacetic acid EDTA ), 1% phytic IP 6), 9% etidronic HEDP ) or distilled water DW ). was quantified ELISA . proliferation dental pulp stem cells DPSC s) conditioned...
Aim: In this study, we aimed to therapeutically target eukaryotic elongation factor 2 kinase (eEF-2K) in an vivo triple-negative breast cancer (TNBC) tumor model. Materials & methods: We synthesized a highly monodisperse nanoformulation using polyethylenimine-modified gold nanoparticles (AuNP-PEI) as siRNA delivery vehicle and evaluated gene downregulation. Results: found that AuNP-PEI/eEF-2K was effective for vitro downregulation showed remarkable antitumor efficacy associated with eEF-2K...
Biodegradable implants are promising drug delivery systems for sustained release ocular with the benefits such as minimum systemic side effects, constant concentration at target site and getting cleared without surgical removal. Dry eye syndrome (DES) is a common disease characterized changes in epithelia surface results inflammatory reaction that might lead to blindness. Cyclosporin A (CsA) cyclic peptide frequently employed treatment of DES it needs be applied several times day tear drops...