Wolfram Mittelmeier

ORCID: 0000-0003-0369-3482
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About
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Research Areas
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Orthopedic Infections and Treatments
  • Hip disorders and treatments
  • Bone Tissue Engineering Materials
  • Bone fractures and treatments
  • Advanced materials and composites
  • Orthopedic Surgery and Rehabilitation
  • Dental Implant Techniques and Outcomes
  • Medical Practices and Rehabilitation
  • Musculoskeletal Disorders and Rehabilitation
  • Lower Extremity Biomechanics and Pathologies
  • Spine and Intervertebral Disc Pathology
  • Shoulder Injury and Treatment
  • Musculoskeletal pain and rehabilitation
  • Hip and Femur Fractures
  • Pelvic and Acetabular Injuries
  • Bone and Joint Diseases
  • Dental materials and restorations
  • Bone health and treatments
  • Occupational Health and Performance
  • Infectious Diseases and Tuberculosis
  • Bone health and osteoporosis research
  • Powder Metallurgy Techniques and Materials
  • Knee injuries and reconstruction techniques

University of Rostock
2016-2025

Universitätsmedizin Rostock
2015-2025

Wolfram Research (United States)
2023

University Medical Center
2014-2022

Orthopädische Universitätsklinik
1994-2020

Zentrum für Sportmedizin der Bundeswehr
2020

University of California, Berkeley
2012

Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation
1998-2008

Rostocker Zentrum zur Erforschung des Demografischen Wandels
2005-2007

Klinikum rechts der Isar
1999-2004

The use of finite element analysis (FEA) has grown to a more and important method in the field biomedical engineering biomechanics. Although increased computational performance allows new ways generate complex biomechanical models, area orthopaedic surgery, solid modelling screws drill holes represent limitation their for individual cases an increase costs. To cope with these requirements, different methods numerical screw have therefore been investigated improve its application diversity....

10.1371/journal.pone.0033776 article EN cc-by PLoS ONE 2012-03-28

An enormous economic impact can be observed for infected total knee arthroplasties (TKA). The aim of the present study was to evaluate whether a cost covering treatment TKA is feasible in German DRG System.Average costs were evaluated and compared with matched pair primary TKA. Data generated using health record hospitals' information system. Results regarding personnel material respect financial receipts.A 28 patients diagnosed an included. A significant increase average length stay, use...

10.1100/2012/196515 article EN cc-by The Scientific World JOURNAL 2012-01-01

The parallel-group randomized active-controlled clinical study was conducted to compare the effectiveness of two in-hospital range motion (ROM) exercise programs following total knee arthroplasty (TKA). Continuous passive (CPM) is frequently used increase ROM and improve postoperative recovery despite little conclusive scientific evidence. In contrast, a new active sling-based therapy requires activation joint muscles dynamic stabilization. It hypothesized that higher demands on muscle...

10.1186/1477-7525-12-68 article EN cc-by Health and Quality of Life Outcomes 2014-01-01

Hip resurfacing arthroplasty is being used more and frequently. The small ratio in size between the resurfaced femoral head relatively thick neck raises question of whether range motion sufficient, particularly with regard to high mobility required by younger patients. We analyzed a CAD model.Three-dimensional models natural hip were created from CT scans 8 designs prostheses (head diameter 42 mm 54 combined hemispherical cup) implanted virtual sense. simulated 3 different leg positions was...

10.1080/17453670810016803 article EN Acta Orthopaedica 2008-01-01

A poly(D,L-lactic acid) surface coating (PDLLA) has been developed to optimize interactions at the implant-tissue interface. Mechanical and allergological characteristics were evaluated in present study elucidate possible indications limitations prior clinical application. Implants of stainless steel Ti-6Al-4V Co-Cr-Mo alloys coated with PDLLA, mechanical stability was studied during intramedullary implantation into rat human cadaver bones dilation coronary artery stents. Elongation...

10.1016/j.orthres.2005.02.003 article EN Journal of Orthopaedic Research® 2005-03-16

Total knee arthroplasty can be considered as a reliable surgical procedure with good long-term clinical result. However, implant failure due to particle induced aseptic loosening well the aspect of hypersensitivity metal ions still remains an emerging issue.The purpose this prospective international multi-centre study was evaluate and radiological outcomes reliability unconstrained Multigen Plus Knee System new BIOLOX® delta ceramic femoral component. Cemented total performed on 108 patients...

10.2174/1874325001206010172 article EN cc-by The Open Orthopaedics Journal 2012-04-20

Total knee arthroplasties have reached a high grade of quality and safety, but most often fail because aseptic implant loosening caused by polyethylene wear debris. Wear is generated at the articulating surfaces, e.g. third-body particles. The objective this experimental study was to determine tibial inserts combined with metallic ceramic femoral components under conditions initiated bone cement testing using cemented unconstrained bicondylar endoprosthesis (Multigen Plus CR system)...

10.5301/ijao.5000189 article EN The International Journal of Artificial Organs 2013-01-01

Implant-associated infections commonly result from biofilm‑forming bacteria and present severe complications in total joint arthroplasty. Therefore, there is a requirement for the development of biocompatible implant surfaces that prevent bacterial biofilm formation. The study coated titanium samples with thin, rapidly corroding layer magnesium, which were subsequently investigated respect to their antibacterial cytotoxic surface properties using Staphylococcus epidermidis (S. epidermidis)...

10.3892/mmr.2017.6218 article EN cc-by-nc-nd Molecular Medicine Reports 2017-02-17

Objectives Total joint arthroplasty is one of the most frequent and effective surgeries today. However, despite improved surgical techniques, a significant number implant-associated infections still occur. Suitable in vitro models are needed to test potential approaches prevent infection. In present study, we aimed establish an co-culture setup human primary osteoblasts S. epidermidis model onset infections, analyze antimicrobial implant surfaces coatings. Materials Methods For initial...

10.1371/journal.pone.0151534 article EN cc-by PLoS ONE 2016-03-16

Background: All-day braces are predominantly used for the conservative treatment of adolescent idiopathic scoliosis (AIS). The Charleston Bending Brace is a pure nighttime brace. aim this study was to investigate primary in-brace correction main curve AIS when treated with Brace. Specifically, factors influencing major were examined. Methods: retrospective analysis included 97 patients who between October 2010 and September 2020. Patients secondary or orthotic pretreatment excluded....

10.3390/life15030448 article EN cc-by Life 2025-03-12

Chronic pain syndrome poses a significant challenge to healthcare systems worldwide, affecting millions of individuals and resulting in reduced quality life substantial socio-economic costs. This prospective, non-interventional, single-center study evaluated the effectiveness four-week interdisciplinary multimodal therapy (IMPT) program incorporating neuromuscular training with HUBER® 360 evolution device. The included 66 patients diagnosed chronic disorder, divided into an intervention...

10.3390/life15040576 article EN cc-by Life 2025-04-01

Quality assurance in arthroplasty is based on established systems such as the German Arthroplasty Registry (EPRD) and EndoCert certification system. These enable continuous improvement quality of care through targeted feedback audits. After introduction semi-annual EPRD hospital evaluations, detailed analyses comparisons their revision rates for hip knee arthroplasties (THA, TKA) became possible hospitals. The aim this study was to compare evaluate standardised ratios (SRR) clinics. analysed...

10.1007/s00132-025-04639-2 article EN cc-by Deleted Journal 2025-04-01

AbstractBackground Dislocation after replacement may be caused by poor implant design or positioning, the surgical approach taken. We evaluated infl uence of head and neck on range motion stability (with respect to risk dislocation) in total hip endoprostheses. Material methods Using a test device, we determined afforded different sizes geometries for various positions. Results Increasing diameter led an enhancement as well resistance against subluxation, thus improved any movement...

10.1080/00016470410001178-1 article EN Acta Orthopaedica Scandinavica 2004-01-01
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