A5078248295- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Polar Research and Ecology
- Plant-Microbe Interactions and Immunity
- Ginseng Biological Effects and Applications
- Protist diversity and phylogeny
- Environmental DNA in Biodiversity Studies
- Neurobiology and Insect Physiology Research
- Plant Pathogens and Fungal Diseases
- Aquaculture Nutrition and Growth
- Algal biology and biofuel production
- Wastewater Treatment and Nitrogen Removal
- Bacteriophages and microbial interactions
- RNA modifications and cancer
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Agriculture, Soil, Plant Science
- Heavy metals in environment
- Phytochemistry and Biological Activities
- Constructed Wetlands for Wastewater Treatment
- Epigenetics and DNA Methylation
- Circular RNAs in diseases
- Plant Pathogenic Bacteria Studies
- RNA Research and Splicing
- Fish Ecology and Management Studies
Shandong University
2013-2025
Beijing Museum of Natural History
2019-2025
Shandong Provincial Hospital
2013-2025
Dezhou University
2003-2025
Shanghai Normal University
2025
Shandong First Medical University
2021-2025
Liaocheng People's Hospital
2025
Kunming University
2013-2024
Chinese Academy of Sciences
2013-2024
Anhui Normal University
2019-2024
Abstract Delineating cohesive ecological units and determining the genetic basis for their environmental adaptation are among most important objectives in microbiology. In last decade, many studies have been devoted to characterizing diversity microbial populations address these issues. However, impact of extreme conditions, such as temperature salinity, on ecology evolution remains unclear so far. order better understand mechanisms adaptation, we studied (pan)genome Exiguobacterium, a...
In recent years, bacterial-based biocontrol agents (BCA) have become a new trend for the control of fungal diseases such as fusarium wilt that seriously threaten yield and quality cucumber, which are transmitted through infested soil water. This study was set out with aim figuring mechanism isolated rhizobacterial strain Paenibacillus polymyxa PJH16 in preventing Fusarium oxysporum f. sp. cucumerinum ( Foc ). Biocontrol growth-promoting experiments revealed bacterial causes effective...
Panax ginseng is widely used as functional food and traditional Chinese medicine. To satisfy the market supply medication safety, biofertilizers are agents to stimulate growth production of P. ginseng.In this study, we high-throughput sequencing quantitative polymerase chain reaction analyze microbial community in soils treated with during development stages ginseng. Ginsenoside content was detected using high-performance liquid chromatography analysis evaluate effects biofertilizer...
Cucumber Fusarium wilt is a worldwide soil-borne disease that seriously restricts the yield and quality of cucumber. The rhizosphere soil microbiome, as first line defense against pathogens invading plant roots, plays key role in immune formation function. purpose this study was to reveal microecological factors dominant microbial flora affecting cucumber resistance susceptibility by analyzing physical chemical properties with different degrees wilt, thereby laying foundation establish core...
MicroRNAs (miRNAs) are small, noncoding RNAs that believed to play fundamental roles in tumorigenesis and tumor development at the posttranscriptional level, as negative regulators of gene expression. This study was designed evaluate expression anticancer effect miR-519d ovarian cancer.The levels cancer cells tissues were detected by TaqMan quantitative reverse transcriptase-polymerase chain reaction (TaqMan qRT-PCR; Life Technologies, Carlsbad, CA, USA). The effects on cell proliferation...
Strain B528-3 T , a Gram-stain-negative, rod-shaped, aerobic, facultatively psychrophilic bacterium with polar flagella, was isolated from an ice core drilled Muztagh Glacier, Xinjiang, China. The novel isolate classified into the genus Massilia . 16S rRNA gene sequence of shares pairwise similarity less than 97 % those all type strains major fatty acids strain were summed feature 3 (C 16:1 ω7 c and/or iso-C 15:0 2-OH) (57.31 %), C 16:0 (11.46 %) and 18:1 (14.72 %). predominant isoprenoid...
One major issue in reducing cucumber yield is the destructive disease Cucumber ( Cucumis sativus L.) wilt caused by Fusarium oxysporum f. sp. cucumerinum Foc ). When using isolate VJH504 isolated from rhizosphere soil and identified as Bacillus velezensis , growth of double culture experiment was effectively inhibited. Phenotypic, phylogenetic, genomic analyses were conducted to enhance understanding its biocontrol mechanism. According result phenotype analysis, B. could inhibit fusarium...
Recent advances in the synthesis of multi-functional nanoparticles have opened up tremendous opportunities for targeted delivery genes interest. Cationic solid lipid (SLN) can efficiently bind nucleic acid molecules and transfect vitro. Few reports combined SLN with therapy using decoy oligodeoxynucleotides (ODN). In present study, we prepared to encapsulate STAT3 ODN; then, properties vitro behavior SLN-STAT3 ODN complexes were investigated. taken by human ovarian cancer cells significantly...
Glioma has been investigated for decades, but the prognosis remains poor because of rapid proliferation, its aggressive potential, and resistance to chemotherapy or radiotherapy. The mammalian target rapamycin (mTOR) is highly expressed regulates cellular proliferation cell growth. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene transcription translation via up-regulating down-regulating levels miRNAs. This study was conducted explore molecular functions miR-199a-3p in...
Diosgenin, mainly extracted from wild diosgenin-contained Dioscorea species, is a well-known starting material of steroidal and contraceptive drugs. However, due to large market demand increasingly ecological damage, species resources available have been gradually declining. Therefore, identification new potential distribution necessary for diosgenin production.In this study, occurrence dataset (1808 data points) was obtained Eastern Asia, Southern North America Africa. Along with the six...
Spalt-like transcription factor 4 (SALL4), a oncogene, is known to participate in multiple carcinomas, and up-regulated glioma. However, its actual role underlying mechanisms the development of glioma remain unclear. The present study explored molecular functions SALL4 promoting cell proliferation expression level 69 human samples six non-tumor brain tissues was determined using real-time polymerase chain reaction (PCR). Then, we transfected U87 U251 lines with siRNA, assessed cellular cycle...
Fish are among the main target groups when conducting biomonitoring and ecological assessment of aquatic environments. Environmental DNA (eDNA) metabarcoding provides a unique opportunity to enhance throughput, precision, standardization. However, few fish monitoring studies based on eDNA have been conducted at basin scale. Taking Dianchi Lake three inflowing rivers (Panlong River, Baoxiang Chai River) as research objects, this study monitored diversity via metabarcoding, Index Biological...
Cistanche deserticola, a holoparasitic plant widely used in traditional Chinese medicine, relies on chemical signals from its host plant, Haloxylon ammodendron, to initiate seed germination and haustorium induction. This study employed UPLC-MS/MS analyze the root metabolites of H. ammodendron. The results showed that 11 substances such as phenolic acids, flavonoids, alkaloids were mainly contained roots among which acids accounted for largest proportion, accounting 18.00% winter samples...
Background Heat shock factor 1 ( HSF1 ), the principal transcriptional regulator of cellular stress responses, has been exhibited to play a role in progression various human cancer types. However, function endometrial (EC) not yet evaluated. Objective This study examined expression and EC. Methods Immunohistochemistry was performed explore level 135 tissue specimens. The relationship between EC patients’ clinicopathological characteristics analyzed. Quantitative reverse-transcriptase...
ABSTRACT The nuclear pore complex plays a key role in transport of immune signals. Two nucleoporins, CONSTITUTIVE EXPRESSION OF PR GENES 5 (CPR5) and GUANYLATE‐BINDING PROTEIN‐LIKE 3 (GBPL3), have been implicated plant immunity. Arabidopsis GBPL family comprises three members. While GBPL1 GBPL3 were discovered to form an circuit, the GBPL2 remains unknown. Through genetic screening, we identified gain‐of‐function mutation , named suppressor cpr5 23 ( scpr23 ), that fully suppresses mutant...
Herbgenomics provides a global platform to explore the genetics and biology of herbs on genome level. Panax ginseng C.A. Meyer is an important medicinal plant with numerous pharmaceutical effects. Previous reports mainly discussed transcriptome at organ However, based mass spectrometry imaging analyses, ginsenosides varied among different tissues. In this work, root was separated into three tissues-periderm, cortex stele-each for five duplicates. The chemical analysis were conducted...