A5044270635- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- Pneumonia and Respiratory Infections
- Antimicrobial Resistance in Staphylococcus
- Mosquito-borne diseases and control
- Vector-borne infectious diseases
- Diagnosis and treatment of tuberculosis
- Nausea and vomiting management
- Electroconvulsive Therapy Studies
- Fungal Infections and Studies
- Anesthesia and Sedative Agents
- Leprosy Research and Treatment
- Bacterial Identification and Susceptibility Testing
- Pneumocystis jirovecii pneumonia detection and treatment
- Viral Infections and Vectors
- Plant Pathogens and Resistance
- Clostridium difficile and Clostridium perfringens research
- Respiratory viral infections research
- Antifungal resistance and susceptibility
- Yersinia bacterium, plague, ectoparasites research
- Healthcare cost, quality, practices
- Health Systems, Economic Evaluations, Quality of Life
- Peripheral Neuropathies and Disorders
- Syphilis Diagnosis and Treatment
University of Mississippi Medical Center
2004-2022
Jackson Memorial Hospital
2011-2020
Mississippi State Department of Health
1959-2018
G.V. (Sonny) Montgomery VA Medical Center
1959-2017
University of Mississippi
2013
University of South Carolina
2003
United States Department of Health and Human Services
1997
National Center for Infectious Diseases
1997
Centers for Disease Control and Prevention
1997
United States Public Health Service
1997
Candida parapsilosis is an important cause of bloodstream infections in the health care setting. We investigated a large C. outbreak occurring community hospital and conducted case-control study to determine risk factors for infection. identified 22 cases infection with parapsilosis: 15 confirmed 7 possible. The associated increased included hospitalization intensive unit (adjusted odds ratio, 16.4; 95% confidence interval, 1.8 148.1) receipt total parenteral nutrition 9.2; 0.9 98.1)....
Abstract Acute weakness associated with West Nile virus (WNV) infection has previously been attributed to a peripheral demyelinating process (Guillain-Barré syndrome); however, the exact etiology of this acute flaccid paralysis not systematically assessed. To thoroughly describe clinical, laboratory, and electrodiagnostic features syndrome, we evaluated that developed in seven patients setting WNV infection, consecutively identified four hospitals St. Tammany Parish New Orleans, Louisiana,...
Randomized controlled trials have demonstrated that the newest latent tuberculosis (LTBI) regimen, 12 weekly doses of directly observed isoniazid and rifapentine (3HP), is as efficacious 9 months isoniazid, with a greater completion rate (82% vs 69%); however, 3HP has not been assessed in routine healthcare settings. Observational cohort LTBI patients receiving through 16 US programs was used to assess treatment completion, adverse drug reactions, factors associated discontinuation. Of 3288...
Abstract Poliomyelitis has recently been identified as a cause of muscle weakness in patients with West Nile virus (WNV) infection. However, the clinical spectrum WNV‐associated not described. We reviewed data on 13 WNV Patients were classified into one three distinct groups based features. Group 1 comprised five who developed acute flaccid paralysis, four meningoencephalitis and without fever or other signs Paralysis was asymmetric, involved from to limbs individual patients....
Aims of the guidelines These guidelines, drawn up by a multidisciplinary group clinicians and lay workers active in management pregnant women infected with HIV, aim to give up-to-date information on interventions reduce risk mother child transmission virus. The evidence use prevent HIV has been graded according strength data as per definitions US Agency for Health Care Policy Research [1]. Weighted combination antiretroviral therapy (ART) treatment infection se is presented BHIVA adults...
In 1994, an apparent outbreak of atypical genital ulcers was noted by clinicians at the sexually transmitted disease clinic in Jackson, Mississippi. Of 143 patients with tested a multiplex polymerase chain reaction (PCR) assay, 56 (39%) were positive for Haemophilus ducreyi, 44 (31%) herpes simplex virus, and 27 (19%) Treponema pallidum; 12 (8%) >1 organism. 136 human immunodeficiency virus (HIV) serology, 14 (10%) HIV-seropositive, compared none 200 without (P < .001). HIV-1 DNA detected...
Rationale: More information on risk factors for death from tuberculosis in the United States could help reduce mortality rate, which has remained steady more than a decade.Objective: To identify tuberculosis-related adults.Methods: We performed retrospective study of 1,304 adults with who died before treatment completion and 1,039 frequency-matched control subjects completed 2005 to 2006 13 states reporting 65% U.S. cases. used in-depth record abstractions standard algorithm classify deaths...
Infectious complications associated with electroconvulsive therapy (ECT) are extremely unusual. When five of nine patients undergoing ECT at one facility on June 20, 1996 developed Staphylococcus aureus bloodstream infection (BSI), an investigation was initiated. A retrospective cohort study, a procedure review, and observational microbiologic studies were performed. case defined as any patient who had Facility from 1, 1995 through S. BSI <30 days after ECT. The post-ECT rate significantly...
Three native-born patients from the Mississippi Delta presented with leprosy over a 13-month period. None had history of foreign travel, contact each other, or known patients. Two patients' lesions lacked anesthesia, and all armadillo exposure. These cases add to association exposure subsequent development leprosy.
OmpT is a protease associated with the outer membrane of Escherichia coli and possesses high degree homology to plasminogen activator, Pla, Yersinia pestis. We show here that from intact cells can indeed activate plasminogen. Clinical specimens E. were examined for activity ompT gene. Few isolates (12%) found be positive acitivity, whereas most (77%) carried ompt gene expressed cloned In this report we present evidence suggesting surface architecture influences may indicative pathogenic...
Infectious complications associated with electroconvulsive therapy (ECT) are extremely unusual.When five of nine patients undergoing ECT at one facility on June 20, 1996 developed Staphylococcus aureus blood-stream infection (BSI), an investigation was initiated. A retrospective cohort study, a procedure review, and observational microbiologic studies were performed. case defined as any patient who had Facility from 1, 1995 through S. BSI <30 days after ECT. The post-ECT rate significantly...
The Mississippi State Department of Health tuberculosis program serves a rural southeastern US state 2.9 million people in an area 121,489 km(2) (46,907 square miles). Statewide, directly observed therapy (DOT) began 1986. To evaluate the program's effectiveness, trends Centers for Disease Prevention and Control indicators 1981-2005 were compared found to be significant (P < 0.0001). Inclusion rifampin pyrazinamide regimens was reviewed. An annual decline cases case rates 1990, falling by...
Isoniazid-induced seizures are a rare adverse reaction especially in immunocompetent adults. We report case of healthy man with shortly after ingestion his first therapeutic dose isoniazid rifapentine therapy for treatment latent tuberculosis infection. Only 6 other similar cases reported the literature.
This chapter reviews the underlying principles of tuberculosis (TB) chemotherapy, medical management, and current treatment recommendations. TB is caused by members Mycobacterium complex, with M. being responsible for vast majority disease. Early in history anti-TB highly effective agent streptomycin (SM) was applied as monotherapy. Current first-line regimens consist three or four agents that, concert, can eradicate organisms within all compartments prevent development drug resistance....
We present the first reported case of Sporopachydermia cereana in United States. The patient, a 58-year-old neutropenic woman with acute myelogenous leukemia, had blood cultures initially identified as Candida specie, but then S. cereana. She responded to antifungal therapy concurrent recovery her counts.
Selection of the luteinizing hormone (LH) response to exogenous gonadotrophin-releasing (GnRH) in sheep has resulted establishment two lines (High and Low) with a fivefold difference pituitary sensitivity GnRH. The effect selection on gonadotrophin gene expression presence or absence an challenge twenty-week-old ram lambs from both was examined. Before treatment either GnRH saline, LH follicle-stimulating (FSH) concentrations were significantly higher High line than Low animals (LH FSH: P <...
The objective of this study was to investigate risk factors associated with tuberculosis (TB) transmission that caused by Mycobacterium strain MS0006 from 2004 2009 in Hinds County, Mississippi.