A5102721766- Lymphoma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Multiple Myeloma Research and Treatments
- CNS Lymphoma Diagnosis and Treatment
- Congenital Anomalies and Fetal Surgery
- Parasitic infections in humans and animals
- Acute Myeloid Leukemia Research
- Breast Cancer Treatment Studies
- Eosinophilic Disorders and Syndromes
- Platelet Disorders and Treatments
- Cutaneous lymphoproliferative disorders research
- Parasitic Infections and Diagnostics
- Breast Implant and Reconstruction
- Viral-associated cancers and disorders
- vaccines and immunoinformatics approaches
- Occupational exposure and asthma
- Parvovirus B19 Infection Studies
- Chronic Lymphocytic Leukemia Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Salivary Gland Tumors Diagnosis and Treatment
- Circular RNAs in diseases
- Occupational and environmental lung diseases
- Public Health and Environmental Issues
- Protein Degradation and Inhibitors
- RNA Research and Splicing
Fundación Santa Fe de Bogotá
2013-2024
Universidad del Rosario
2019
Pontificia Universidad Javeriana
2017
Délégation Paris 7
2013-2016
Université Paris Cité
2011-2016
Sorbonne Paris Cité
2013-2016
Inserm
2011-2016
Hôpital Saint-Louis
2011-2015
Universidad de Los Andes
2013
Hospital General de México
2011
Background According to the current World Health Organization Classification of Lymphoid Tumours, follicular lymphoma is subclassified into three grades according number centroblasts. Follicular grade 3 can be further divided types A and B. Almost all available genetic data on 3B lymphomas have been generated from tumors with an additional diffuse large B-cell component. The purely type a rare neoplasm.Design Methods We performed detailed immunohistochemical (CD10, IRF4/MUM1, BCL2, Ig light...
The pig is a vital link in the transmission cycle of Taenia solium, cestode responsible for human-porcine cysticercosis. Infected pigs also represent an important source economic loss to farmers developing countries. Past efforts find adequate therapeutic regimen treat this parasitic disease swine have failed because low efficacy, high cost, side effects, or need multiple doses. In randomized, no treatment-controlled study, efficacy and safety oxfendazole praziquantel treatment porcine...
Taenia solium cysticercosis is an important public health problem in developing countries. Oxfendazole has been shown to be highly effective against porcine cysticercosis, when given as a single dose at 30 mg/kg bodyweight. This dose, however, was estimated from experience with albendazole. A controlled dose‐response trial therefore undertaken determine the efficacy and safety of three concentrations oxfendazole. Twenty‐four naturally parasitised pigs were divided into four groups treated...
Human Taenia solium cysticercosis is a major cause of epilepsy in developing countries, and porcine infection causes widespread economic losses because infested pork. Recently, the use oxfendazole (OFZ) for provided, first time, an effective, single-dose treatment. We performed controlled study to determine time required between treatment with single dose OFZ death cysticerci define its applicability as preslaughter or field control measure. Twenty naturally infected pigs were included this...
There is a well-established association between aging and the onset of metastasis. Although mechanisms through which age impinges upon malignant phenotype remain uncharacterized, role senescent microenvironment has been emphasized. We reported previously that human epithelial cells undergo telomere-driven chromosome instability (T-CIN) display global microRNA (miR) deregulation develop migration invasion capacities. Here, we show post-crisis are not able to form tumors unless provided. The...
Multiple myeloma is the second most frequent hematologic malignancy worldwide with high morbidity and mortality. Although it considered an incurable disease, enhanced understanding of this neoplasm has led to new treatments, which have improved patients’ life expectancy. Large amounts data been generated through different studies in settings clinical trials, prospective registries, real-world cohorts, incorporated laboratory tests, flow cytometry, molecular markers, cytogenetics, diagnostic...
An 82-years old Hispanic woman with a past medical history significant for pulmonary thromboembolism on oral anticoagulation, rheumatoid arthritis, and hypertension developed new onset thrombocytopenia.Small clonal B-cells populations (SCBP) also known as monoclonal B-cell lymphocytosis was found part of the workup an idiopathic thrombocytopenia lead ultimately to diagnosis parotid primary follicular lymphoma coexisting Warthin tumor involving bone marrow in small extent oncocytic papilloma...
// Martha Romero 1,2,3,* , Guillaume Gapihan 1,2,* Luis Jaime Castro-Vega 4 Andrés Acevedo 3 Li Wang 1,5 Zhao Wei Morad El Bouchtaoui 1 Mélanie Di Benedetto Philippe Ratajczak 1,2 Jean-Paul Feugeas 1,6 Catherine Thieblemont 7 Carlos Saavedra and Anne Janin 1,2,8 Université-Paris-Diderot, Sorbonne-Paris-Cité, Laboratoire de Pathologie, UMR-S-1165, Paris, France 2 INSERM, U1165-Paris, Hospital-Universitario-Fundación-Santa-Fe-de-Bogotá, Pathology-Department, Bogotá, Colombia UMR970,...
A female patient in her 30s presented to the emergency department with a 10-day history of fever, weakness and diaphoresis. Subsequent investigations revealed diagnosis haemophagocytic syndrome, secondary disseminated non-tuberculous mycobacterial infection affecting bone marrow, lungs, lymph nodes skin. The marrow culture confirmed presence Mycobacterium avium infection. patient’s syndrome was managed using HLH-2004 chemoimmunotherapy, M. treated combination clarithromycin, ethambutol,...
During July 7th and 8th of 2008, the First Colombian Consensus Conference for Immunophenotyping Hematological Malignancies was carried out in Cali, Colombia, with representatives from Argentina, Chile, Perú México. The consensus included professionals laboratory field clinicians different institutions that routinely operate clinical flow cytometry an emphasis on lymphoma leukemia immunophenotyping.In this medical indications use detection hematological malignancies, technical considerations...
Introduction: Coal worker’s pneumoconiosis is caused by the inhalation of coal dust and its accumulation in lungs after several years exposure.Objective: To determine prevalence underground mining workers exposed to Cundinamarca, Colombia, association with their spirometry results respiratory symptoms.Materials methods: Cross-sectional study conducted on 215 who were administered a questionnaire symptoms. For each worker chest radiograph was taken according criteria International Labor...
Introducción: dentro de los subtipos linfoma, el linfoma células del manto o anteriormente denominado linfocítico intermedio corresponde a 3-10% no Hodgkin B. El tratamiento se enfoca según la clasificación paciente, edad, estado funcional y comorbilidades, lo cual está directamente relacionado con capacidad recibir un intensivo trasplante. Es importante homogeneizar conductas fin ofrecer las mejores alternativas bajo contexto colombiano, pues actualmente existen diferentes opciones...
Las neoplasias hematolinfoides son consideradas de alto costo y impacto en la calidad vida, por esta razón, el uso pruebas diagnósticas sobre todo seguimiento como cuantificación enfermedad mínima residual medible, sigue siendo una herramienta para determinar pronóstico, considerando las nuevas tecnologías importancia estandarizar procesamiento. Objetivo: estructurar serie consideraciones común acuerdo expertos, medible (EMR) cinco patologías hematológicas, contexto colombiano. Métodos: se...
Central nervous system infiltration by acute leukemia is a poor prognosis variable, and conventional cytology the gold standard for its diagnosis; technique highly specific but not sensitive. To improve diagnosis, flow cytometry has been used in different studies, showing greater sensitivity detection of leukemic cells. This study aimed to evaluate presence tumor cells flowcytometry cytology, cerebrospinal fluid from patients with as well relationship clinical biological parameters. In...
Introduction. 60-80% of patients with acute B lymphoblastic leukemia show genetic abnormalities that influence the prognosis disease and biology tumor. Objective. To analyze different in children, its relationship to immunophenotype proliferative rate compared normal cell precursors. Materials methods. A total 44 samples were studied by flow cytometry for immunophenotype, DNA content RT-PCR translocations t(9;22), t(12;21), t(4;11) t(1;19). Using a hierarchical cluster analysis some...