A5087085225- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Osteoarthritis Treatment and Mechanisms
- Autoimmune and Inflammatory Disorders Research
- Bone and Joint Diseases
- Reproductive Biology and Fertility
- Reproductive Health and Technologies
- Ovarian function and disorders
- Musculoskeletal synovial abnormalities and treatments
- Tendon Structure and Treatment
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Vitamin D Research Studies
- Knee injuries and reconstruction techniques
- Medical Imaging and Pathology Studies
- Orthopedic Surgery and Rehabilitation
- Peripheral Nerve Disorders
- Infrared Thermography in Medicine
- Lower Extremity Biomechanics and Pathologies
- Ocular Diseases and Behçet’s Syndrome
- Dermatology and Skin Diseases
- Bone health and treatments
- Medical Imaging and Analysis
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Shoulder Injury and Treatment
Radboud University Nijmegen
2014-2024
Radboud University Medical Center
2014-2024
Kocaeli Üniversitesi
2024
Inonu University
2004-2016
Pain and Rehabilitation Medicine
2006
American Physical Therapy Association
1999-2005
Turgut Özal Tıp Merkezi
1998-2004
BACKGROUND: Vascular Ehlers-Danlos syndrome (vEDS) is a rare connective tissue disorder with high risk for arterial, bowel, and uterine rupture, caused by heterozygous pathogenic variants in COL3A1 . The aim of this cohort study to provide further insights into the natural history vEDS describe genotype-phenotype correlations Dutch multicenter optimize patient care increase awareness disease. METHODS: Individuals throughout Netherlands were included. phenotype was charted retrospective...
The aim of this study was to investigate and compare the therapeutic effect three different combinations in conservative treatment carpal tunnel syndrome (CTS) by means clinical electrophysiological studies. included tendon- nerve-gliding exercises combination with splinting, ultrasound splinting ultrasound, exercises. A total 28 female patients (56 wrists) electrophysiologic evidence bilateral CTS were studied. In all patient groups, significantly effective immediately 8 weeks after...
How do female patients experience fertility preservation (FP) consultation (FPC) with a specialist in reproductive medicine and subsequent decision-making on FP? Most had positive experiences FPC, but negative were found to be associated decisional conflict decision regret. When confronted need for gonadotoxic treatment, girls young women will have make an irreversible regard FP. Patients may develop regret about their during follow-up. Patients' opportunities ask questions FPC knowledge FP...
What changes can be detected in fertility preservation (FP) counselling (FPC) over time and what are the determinants associated with referral of newly diagnosed female cancer patients, aged 0–39 years, to a specialist reproductive medicine for FPC? Although absolute number patients receiving FPC increased time, only 9.8% all potential (aged years) were referred 2011 disparities found respect patients' age, diagnosis healthcare provider-related factors. Referral rates prior start gonadotoxic...
What are the decisive factors in fertility preservation (FP) decision-making young women scheduled for gonadotoxic therapy? FP therapy is mainly based on weighing two issues: intensity of wish to conceive a child future and expected burden undergoing treatment. Future importance cancer patients whose reproductive function being threatened by oncological therapy. To prevent or reduce severe psychological effects infertility as well feelings regret about their decision after treatment, quality...
Falls among the elderly are associated with a high morbidity and mortality can involve high-cost medical interventions. The risk of falls often remains undiagnosed until an episode occurs but if is high, preventative measures could be introduced.This 6-month prospective study investigated whether different postural clinical fear falling (FOF) itself predict future in postmenopausal women aged > or =50 years.125 were studied comparing outcome fallers vs. non-fallers within follow-up period....
25(OH)D deficiency has been associated with significantly worse physical performance in individuals normal renal function. We examined the function, muscle strength and balance age- gender-matched 25 Stage 3 - 4 CKD patients 47 5 on peritoneal dialysis (PD) vitamin D by objective methods evaluated effect of replacement tests: "timed up go" (TUG) test, gait velocity timed chair stand stair climb dynamic tests (TUG postural stability test), static test (functional reach test) these two groups....
To assess the frequency of juvenile onset ankylosing spondylitis (JOAS) in Turkish patients with AS and to compare adult (AOAS) a cross-sectional study design.A total 322 were recruited from joint database 5 university hospitals eastern Turkey.Patients JOAS (n = 43, 13.4%) had significantly longer diagnostic delay (9.21 vs 5.08 yrs), less severe axial involvement more prevalent uveitis (OR 2.92, 95% CI 1.25-6.79), peripheral at 3.25, 1.51-6.98, adjusted for current age; OR 2.26, 1.07-4.76,...
Background and Objectives: Measurement of the femoral cartilage thickness by using in-vivo musculoskeletal ultrasonography (MSUS) has been previously shown to be a valid reliable method in previous studies; however, our best notice, normative
What are healthcare professionals' barriers and strategies for improvement in female oncofertility care?Professionals perceived knowledge, attitude organization of care suggested to improve care.The potential loss fertility is one the most important undesirable side effects cancer treatment women reproductive age. Unfortunately, despite guideline recommendations, not all patients informed about their risks referred preservation (FP) counselling. Insight into discussing FP appropriate...
Coffin-Siris and Nicolaides-Baraitser syndromes are recognizable neurodevelopmental disorders caused by germline variants in BAF complex subunits. The SMARCC2 BAFopathy was recently reported. Herein, we present clinical molecular data on a large cohort.Clinical symptoms for 41 novel 24 previously published affected individuals were analyzed using the Human Phenotype Ontology. For genotype-phenotype correlations, standardized grouped into non-truncating likely gene-disrupting (LGD) variants....
The aim of this study is to determine whether the postural changes in ankylosing spondylitis (AS) affected stability.A total 64 patients with a diagnosis AS and 50 healthy volunteers were included study. divided into two groups according tragus-to-wall distance<15 cm (Group I, n=30) >or=15 II, n=34). control group III) consisted volunteers. stability was evaluated Biodex Stability System (BSS). results Antero-Posterior Index (APSI), Medio-Lateral (MLSI) Overall (OSI) evaluated.There...
To investigate discrimination ability of the Assessment Spondyloarthritis International Society (ASAS) endorsed disease activity score (ASDAS) versions evaluating low and high in an unselected group patients with ankylosing spondylitis (AS).Patients consecutively included into joint database five university hospitals were analyzed for or according to different criteria. Standardized mean differences (SMD) two ASDAS evaluated.The (back pain, morning stiffness, patient global pain/swelling...
Objective: Rheumatoid arthritis (RA) is a chronic and disabling disease frequently effects physical psychological well being. The aim of the present study was to determine impact status on health related quality life in pa
Summary Objectives: vitamin D is important for muscle function and it affects different aspects of metabolism. This study aim to determine whether serum 25(OH) levels are related lung functions, physical performance balance in patients with chronic obstructive pulmonary disease (COPD). Methods: 90 COPD 57 healthy controls tests, tests (time up go, gait velocity test, sit-to-stand isometric strength, isokinetic strength), static (functional reach test) dynamic go) the association 25(OH)D were...
Pitt-Hopkins syndrome (PTHS) is a neurodevelopmental disorder caused by pathogenic variants in TCF4, leading to intellectual disability, specific morphological features, and autonomic nervous system dysfunction. Epigenetic dysregulation has been implicated PTHS, prompting the investigation of DNA methylation (DNAm) "episignature" PTHS for diagnostic purposes variant reclassification functional insights into molecular pathophysiology this disorder. A cohort 67 individuals with genetically...
The aim of this study was to investigate the relationship between femoral, tibial and patellar cartilage volume MRI grading articular in patients with knee OA.Articular volumes 65 postmenopausal women were determined by processing images acquired sagittal plane using a fast spin echo proton density-weighted sequence. cartilages divided into 5 compartments including lateral medial tibial, femoral compartments. graded modified Outerbridge classification. Grade 0 indicated intact cartilage,...
Objective. Dynamic carpal tunnel syndrome (CTS) is a subtype of CTS in which symptoms usually subside with rest and return repetitive motions. In this subgroup, nerve conduction studies, performed at rest, are often inconclusive. study, the diagnostic value provocative sonography was evaluated patients dynamic CTS. Methods. Twenty wrists 13 10 control subjects were investigated before immediately after exercises imitating work‐related stresses. addition to conventional indices (palmar...